Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest

Detalhes bibliográficos
Autor(a) principal: Suffredini, I.b.
Data de Publicação: 2004
Outros Autores: Sader, Helio Silva [UNIFESP], Gonçalves, Azizedite Guedes, Reis, Adriana O. [UNIFESP], Gales, Ana Cristina [UNIFESP], Varella, Antonio Drauzio, Younes, Riad Naim
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0100-879X2004000300015
http://repositorio.unifesp.br/handle/11600/2031
Resumo: More than 20% of the world's biodiversity is located in Brazilian forests and only a few plant extracts have been evaluated for potential antibacterial activity. In the present study, 705 organic and aqueous extracts of plants obtained from different Amazon Rain Forest and Atlantic Forest plants were screened for antibacterial activity at 100 µg/ml, using a microdilution broth assay against Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa and Escherichia coli. One extract, VO581, was active against S. aureus (minimum inhibitory concentration (MIC) = 140 µg/ml and minimal bactericidal concentration (MBC) = 160 µg/ml, organic extract obtained from stems) and two extracts were active against E. faecalis, SM053 (MIC = 80 µg/ml and MBC = 90 µg/ml, organic extract obtained from aerial parts), and MY841 (MIC = 30 µg/ml and MBC = 50 µg/ml, organic extract obtained from stems). The most active fractions are being fractionated to identify their active substances. Higher concentrations of other extracts are currently being evaluated against the same microorganisms.
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spelling Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic ForestPlant extractAntibacterial activityScreeningAmazon Rain ForestAtlantic ForestMore than 20% of the world's biodiversity is located in Brazilian forests and only a few plant extracts have been evaluated for potential antibacterial activity. In the present study, 705 organic and aqueous extracts of plants obtained from different Amazon Rain Forest and Atlantic Forest plants were screened for antibacterial activity at 100 µg/ml, using a microdilution broth assay against Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa and Escherichia coli. One extract, VO581, was active against S. aureus (minimum inhibitory concentration (MIC) = 140 µg/ml and minimal bactericidal concentration (MBC) = 160 µg/ml, organic extract obtained from stems) and two extracts were active against E. faecalis, SM053 (MIC = 80 µg/ml and MBC = 90 µg/ml, organic extract obtained from aerial parts), and MY841 (MIC = 30 µg/ml and MBC = 50 µg/ml, organic extract obtained from stems). The most active fractions are being fractionated to identify their active substances. Higher concentrations of other extracts are currently being evaluated against the same microorganisms.Universidade Paulista Laboratório de ExtraçãoUniversidade Federal de São Paulo (UNIFESP) Laboratório Especial de Microbiologia ClínicaUniversidade Federal do Maranhão Centro de Ciências Biológicas e da SaúdeUNIFESP, Laboratório Especial de Microbiologia ClínicaSciELOAssociação Brasileira de Divulgação CientíficaUniversidade Paulista Laboratório de ExtraçãoUniversidade Federal de São Paulo (UNIFESP)Universidade Federal do Maranhão Centro de Ciências Biológicas e da SaúdeSuffredini, I.b.Sader, Helio Silva [UNIFESP]Gonçalves, Azizedite GuedesReis, Adriana O. [UNIFESP]Gales, Ana Cristina [UNIFESP]Varella, Antonio DrauzioYounes, Riad Naim2015-06-14T13:30:20Z2015-06-14T13:30:20Z2004-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion379-384application/pdfhttp://dx.doi.org/10.1590/S0100-879X2004000300015Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 37, n. 3, p. 379-384, 2004.10.1590/S0100-879X2004000300015S0100-879X2004000300015.pdf0100-879XS0100-879X2004000300015http://repositorio.unifesp.br/handle/11600/2031WOS:000220371600015engBrazilian Journal of Medical and Biological Researchinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-06T23:57:21Zoai:repositorio.unifesp.br/:11600/2031Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-06T23:57:21Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
title Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
spellingShingle Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
Suffredini, I.b.
Plant extract
Antibacterial activity
Screening
Amazon Rain Forest
Atlantic Forest
title_short Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
title_full Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
title_fullStr Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
title_full_unstemmed Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
title_sort Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
author Suffredini, I.b.
author_facet Suffredini, I.b.
Sader, Helio Silva [UNIFESP]
Gonçalves, Azizedite Guedes
Reis, Adriana O. [UNIFESP]
Gales, Ana Cristina [UNIFESP]
Varella, Antonio Drauzio
Younes, Riad Naim
author_role author
author2 Sader, Helio Silva [UNIFESP]
Gonçalves, Azizedite Guedes
Reis, Adriana O. [UNIFESP]
Gales, Ana Cristina [UNIFESP]
Varella, Antonio Drauzio
Younes, Riad Naim
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Paulista Laboratório de Extração
Universidade Federal de São Paulo (UNIFESP)
Universidade Federal do Maranhão Centro de Ciências Biológicas e da Saúde
dc.contributor.author.fl_str_mv Suffredini, I.b.
Sader, Helio Silva [UNIFESP]
Gonçalves, Azizedite Guedes
Reis, Adriana O. [UNIFESP]
Gales, Ana Cristina [UNIFESP]
Varella, Antonio Drauzio
Younes, Riad Naim
dc.subject.por.fl_str_mv Plant extract
Antibacterial activity
Screening
Amazon Rain Forest
Atlantic Forest
topic Plant extract
Antibacterial activity
Screening
Amazon Rain Forest
Atlantic Forest
description More than 20% of the world's biodiversity is located in Brazilian forests and only a few plant extracts have been evaluated for potential antibacterial activity. In the present study, 705 organic and aqueous extracts of plants obtained from different Amazon Rain Forest and Atlantic Forest plants were screened for antibacterial activity at 100 µg/ml, using a microdilution broth assay against Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa and Escherichia coli. One extract, VO581, was active against S. aureus (minimum inhibitory concentration (MIC) = 140 µg/ml and minimal bactericidal concentration (MBC) = 160 µg/ml, organic extract obtained from stems) and two extracts were active against E. faecalis, SM053 (MIC = 80 µg/ml and MBC = 90 µg/ml, organic extract obtained from aerial parts), and MY841 (MIC = 30 µg/ml and MBC = 50 µg/ml, organic extract obtained from stems). The most active fractions are being fractionated to identify their active substances. Higher concentrations of other extracts are currently being evaluated against the same microorganisms.
publishDate 2004
dc.date.none.fl_str_mv 2004-03-01
2015-06-14T13:30:20Z
2015-06-14T13:30:20Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0100-879X2004000300015
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 37, n. 3, p. 379-384, 2004.
10.1590/S0100-879X2004000300015
S0100-879X2004000300015.pdf
0100-879X
S0100-879X2004000300015
http://repositorio.unifesp.br/handle/11600/2031
WOS:000220371600015
url http://dx.doi.org/10.1590/S0100-879X2004000300015
http://repositorio.unifesp.br/handle/11600/2031
identifier_str_mv Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 37, n. 3, p. 379-384, 2004.
10.1590/S0100-879X2004000300015
S0100-879X2004000300015.pdf
0100-879X
S0100-879X2004000300015
WOS:000220371600015
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brazilian Journal of Medical and Biological Research
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 379-384
application/pdf
dc.publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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