Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes

Detalhes bibliográficos
Autor(a) principal: Pepato,M.T.
Data de Publicação: 2001
Outros Autores: Folgado,V.B.B., Kettelhut,I.C., Brunetti,I.L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Medical and Biological Research
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000300014
Resumo: Streptozotocin-diabetic rats were treated for 17 days with a decoction of Eugenia jambolana (Myrtaceae) leaves (15%, w/v) as a substitute for water. Body weight, food and fluid intake, urine volume, glycemia, urinary glucose and urea were evaluated every 5 days. The animals were sacrificed by decapitation and blood samples collected for the determination of glycemia, serum cholesterol, HDL-cholesterol, triglycerides and angiotensin-converting enzyme. The weight of adipose and muscle tissues was also determined. There were no statistically significant differences between treated and untreated rats for any of the biochemical or physiological parameters. We conclude that, at least in this experimental model, Eugenia jambolana leaf decoction has no antidiabetic activity.
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spelling Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetesantidiabetic planthyperglycemiadiabetic ratsEugenia jambolanaStreptozotocin-diabetic rats were treated for 17 days with a decoction of Eugenia jambolana (Myrtaceae) leaves (15%, w/v) as a substitute for water. Body weight, food and fluid intake, urine volume, glycemia, urinary glucose and urea were evaluated every 5 days. The animals were sacrificed by decapitation and blood samples collected for the determination of glycemia, serum cholesterol, HDL-cholesterol, triglycerides and angiotensin-converting enzyme. The weight of adipose and muscle tissues was also determined. There were no statistically significant differences between treated and untreated rats for any of the biochemical or physiological parameters. We conclude that, at least in this experimental model, Eugenia jambolana leaf decoction has no antidiabetic activity.Associação Brasileira de Divulgação Científica2001-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000300014Brazilian Journal of Medical and Biological Research v.34 n.3 2001reponame:Brazilian Journal of Medical and Biological Researchinstname:Associação Brasileira de Divulgação Científica (ABDC)instacron:ABDC10.1590/S0100-879X2001000300014info:eu-repo/semantics/openAccessPepato,M.T.Folgado,V.B.B.Kettelhut,I.C.Brunetti,I.L.eng2001-03-16T00:00:00Zoai:scielo:S0100-879X2001000300014Revistahttps://www.bjournal.org/https://old.scielo.br/oai/scielo-oai.phpbjournal@terra.com.br||bjournal@terra.com.br1414-431X0100-879Xopendoar:2001-03-16T00:00Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)false
dc.title.none.fl_str_mv Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes
title Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes
spellingShingle Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes
Pepato,M.T.
antidiabetic plant
hyperglycemia
diabetic rats
Eugenia jambolana
title_short Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes
title_full Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes
title_fullStr Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes
title_full_unstemmed Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes
title_sort Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes
author Pepato,M.T.
author_facet Pepato,M.T.
Folgado,V.B.B.
Kettelhut,I.C.
Brunetti,I.L.
author_role author
author2 Folgado,V.B.B.
Kettelhut,I.C.
Brunetti,I.L.
author2_role author
author
author
dc.contributor.author.fl_str_mv Pepato,M.T.
Folgado,V.B.B.
Kettelhut,I.C.
Brunetti,I.L.
dc.subject.por.fl_str_mv antidiabetic plant
hyperglycemia
diabetic rats
Eugenia jambolana
topic antidiabetic plant
hyperglycemia
diabetic rats
Eugenia jambolana
description Streptozotocin-diabetic rats were treated for 17 days with a decoction of Eugenia jambolana (Myrtaceae) leaves (15%, w/v) as a substitute for water. Body weight, food and fluid intake, urine volume, glycemia, urinary glucose and urea were evaluated every 5 days. The animals were sacrificed by decapitation and blood samples collected for the determination of glycemia, serum cholesterol, HDL-cholesterol, triglycerides and angiotensin-converting enzyme. The weight of adipose and muscle tissues was also determined. There were no statistically significant differences between treated and untreated rats for any of the biochemical or physiological parameters. We conclude that, at least in this experimental model, Eugenia jambolana leaf decoction has no antidiabetic activity.
publishDate 2001
dc.date.none.fl_str_mv 2001-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000300014
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000300014
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-879X2001000300014
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
dc.source.none.fl_str_mv Brazilian Journal of Medical and Biological Research v.34 n.3 2001
reponame:Brazilian Journal of Medical and Biological Research
instname:Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
instname_str Associação Brasileira de Divulgação Científica (ABDC)
instacron_str ABDC
institution ABDC
reponame_str Brazilian Journal of Medical and Biological Research
collection Brazilian Journal of Medical and Biological Research
repository.name.fl_str_mv Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)
repository.mail.fl_str_mv bjournal@terra.com.br||bjournal@terra.com.br
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