Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes
Autor(a) principal: | |
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Data de Publicação: | 2001 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Medical and Biological Research |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000300014 |
Resumo: | Streptozotocin-diabetic rats were treated for 17 days with a decoction of Eugenia jambolana (Myrtaceae) leaves (15%, w/v) as a substitute for water. Body weight, food and fluid intake, urine volume, glycemia, urinary glucose and urea were evaluated every 5 days. The animals were sacrificed by decapitation and blood samples collected for the determination of glycemia, serum cholesterol, HDL-cholesterol, triglycerides and angiotensin-converting enzyme. The weight of adipose and muscle tissues was also determined. There were no statistically significant differences between treated and untreated rats for any of the biochemical or physiological parameters. We conclude that, at least in this experimental model, Eugenia jambolana leaf decoction has no antidiabetic activity. |
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Brazilian Journal of Medical and Biological Research |
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Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetesantidiabetic planthyperglycemiadiabetic ratsEugenia jambolanaStreptozotocin-diabetic rats were treated for 17 days with a decoction of Eugenia jambolana (Myrtaceae) leaves (15%, w/v) as a substitute for water. Body weight, food and fluid intake, urine volume, glycemia, urinary glucose and urea were evaluated every 5 days. The animals were sacrificed by decapitation and blood samples collected for the determination of glycemia, serum cholesterol, HDL-cholesterol, triglycerides and angiotensin-converting enzyme. The weight of adipose and muscle tissues was also determined. There were no statistically significant differences between treated and untreated rats for any of the biochemical or physiological parameters. We conclude that, at least in this experimental model, Eugenia jambolana leaf decoction has no antidiabetic activity.Associação Brasileira de Divulgação Científica2001-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000300014Brazilian Journal of Medical and Biological Research v.34 n.3 2001reponame:Brazilian Journal of Medical and Biological Researchinstname:Associação Brasileira de Divulgação Científica (ABDC)instacron:ABDC10.1590/S0100-879X2001000300014info:eu-repo/semantics/openAccessPepato,M.T.Folgado,V.B.B.Kettelhut,I.C.Brunetti,I.L.eng2001-03-16T00:00:00Zoai:scielo:S0100-879X2001000300014Revistahttps://www.bjournal.org/https://old.scielo.br/oai/scielo-oai.phpbjournal@terra.com.br||bjournal@terra.com.br1414-431X0100-879Xopendoar:2001-03-16T00:00Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)false |
dc.title.none.fl_str_mv |
Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes |
title |
Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes |
spellingShingle |
Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes Pepato,M.T. antidiabetic plant hyperglycemia diabetic rats Eugenia jambolana |
title_short |
Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes |
title_full |
Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes |
title_fullStr |
Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes |
title_full_unstemmed |
Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes |
title_sort |
Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes |
author |
Pepato,M.T. |
author_facet |
Pepato,M.T. Folgado,V.B.B. Kettelhut,I.C. Brunetti,I.L. |
author_role |
author |
author2 |
Folgado,V.B.B. Kettelhut,I.C. Brunetti,I.L. |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Pepato,M.T. Folgado,V.B.B. Kettelhut,I.C. Brunetti,I.L. |
dc.subject.por.fl_str_mv |
antidiabetic plant hyperglycemia diabetic rats Eugenia jambolana |
topic |
antidiabetic plant hyperglycemia diabetic rats Eugenia jambolana |
description |
Streptozotocin-diabetic rats were treated for 17 days with a decoction of Eugenia jambolana (Myrtaceae) leaves (15%, w/v) as a substitute for water. Body weight, food and fluid intake, urine volume, glycemia, urinary glucose and urea were evaluated every 5 days. The animals were sacrificed by decapitation and blood samples collected for the determination of glycemia, serum cholesterol, HDL-cholesterol, triglycerides and angiotensin-converting enzyme. The weight of adipose and muscle tissues was also determined. There were no statistically significant differences between treated and untreated rats for any of the biochemical or physiological parameters. We conclude that, at least in this experimental model, Eugenia jambolana leaf decoction has no antidiabetic activity. |
publishDate |
2001 |
dc.date.none.fl_str_mv |
2001-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000300014 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000300014 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0100-879X2001000300014 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
dc.source.none.fl_str_mv |
Brazilian Journal of Medical and Biological Research v.34 n.3 2001 reponame:Brazilian Journal of Medical and Biological Research instname:Associação Brasileira de Divulgação Científica (ABDC) instacron:ABDC |
instname_str |
Associação Brasileira de Divulgação Científica (ABDC) |
instacron_str |
ABDC |
institution |
ABDC |
reponame_str |
Brazilian Journal of Medical and Biological Research |
collection |
Brazilian Journal of Medical and Biological Research |
repository.name.fl_str_mv |
Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC) |
repository.mail.fl_str_mv |
bjournal@terra.com.br||bjournal@terra.com.br |
_version_ |
1754302930941378560 |