Cross-talk between neurons and glia: highlights on soluble factors

Detalhes bibliográficos
Autor(a) principal: Gomes,F.C.A.
Data de Publicação: 2001
Outros Autores: Spohr,T.C.L.S., Martinez,R., Moura Neto,V.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Medical and Biological Research
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000500008
Resumo: The development of the nervous system is guided by a balanced action between intrinsic factors represented by the genetic program and epigenetic factors characterized by cell-cell interactions which neural cells might perform throughout nervous system morphogenesis. Highly relevant among them are neuron-glia interactions. Several soluble factors secreted by either glial or neuronal cells have been implicated in the mutual influence these cells exert on each other. In this review, we will focus our attention on recent advances in the understanding of the role of glial and neuronal trophic factors in nervous system development. We will argue that the functional architecture of the brain depends on an intimate neuron-glia partnership.
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spelling Cross-talk between neurons and glia: highlights on soluble factorsneuron-glia interactiontrophic factorsastrocyteneuronnervous systemThe development of the nervous system is guided by a balanced action between intrinsic factors represented by the genetic program and epigenetic factors characterized by cell-cell interactions which neural cells might perform throughout nervous system morphogenesis. Highly relevant among them are neuron-glia interactions. Several soluble factors secreted by either glial or neuronal cells have been implicated in the mutual influence these cells exert on each other. In this review, we will focus our attention on recent advances in the understanding of the role of glial and neuronal trophic factors in nervous system development. We will argue that the functional architecture of the brain depends on an intimate neuron-glia partnership.Associação Brasileira de Divulgação Científica2001-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000500008Brazilian Journal of Medical and Biological Research v.34 n.5 2001reponame:Brazilian Journal of Medical and Biological Researchinstname:Associação Brasileira de Divulgação Científica (ABDC)instacron:ABDC10.1590/S0100-879X2001000500008info:eu-repo/semantics/openAccessGomes,F.C.A.Spohr,T.C.L.S.Martinez,R.Moura Neto,V.eng2001-04-19T00:00:00Zoai:scielo:S0100-879X2001000500008Revistahttps://www.bjournal.org/https://old.scielo.br/oai/scielo-oai.phpbjournal@terra.com.br||bjournal@terra.com.br1414-431X0100-879Xopendoar:2001-04-19T00:00Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)false
dc.title.none.fl_str_mv Cross-talk between neurons and glia: highlights on soluble factors
title Cross-talk between neurons and glia: highlights on soluble factors
spellingShingle Cross-talk between neurons and glia: highlights on soluble factors
Gomes,F.C.A.
neuron-glia interaction
trophic factors
astrocyte
neuron
nervous system
title_short Cross-talk between neurons and glia: highlights on soluble factors
title_full Cross-talk between neurons and glia: highlights on soluble factors
title_fullStr Cross-talk between neurons and glia: highlights on soluble factors
title_full_unstemmed Cross-talk between neurons and glia: highlights on soluble factors
title_sort Cross-talk between neurons and glia: highlights on soluble factors
author Gomes,F.C.A.
author_facet Gomes,F.C.A.
Spohr,T.C.L.S.
Martinez,R.
Moura Neto,V.
author_role author
author2 Spohr,T.C.L.S.
Martinez,R.
Moura Neto,V.
author2_role author
author
author
dc.contributor.author.fl_str_mv Gomes,F.C.A.
Spohr,T.C.L.S.
Martinez,R.
Moura Neto,V.
dc.subject.por.fl_str_mv neuron-glia interaction
trophic factors
astrocyte
neuron
nervous system
topic neuron-glia interaction
trophic factors
astrocyte
neuron
nervous system
description The development of the nervous system is guided by a balanced action between intrinsic factors represented by the genetic program and epigenetic factors characterized by cell-cell interactions which neural cells might perform throughout nervous system morphogenesis. Highly relevant among them are neuron-glia interactions. Several soluble factors secreted by either glial or neuronal cells have been implicated in the mutual influence these cells exert on each other. In this review, we will focus our attention on recent advances in the understanding of the role of glial and neuronal trophic factors in nervous system development. We will argue that the functional architecture of the brain depends on an intimate neuron-glia partnership.
publishDate 2001
dc.date.none.fl_str_mv 2001-05-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000500008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000500008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-879X2001000500008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
dc.source.none.fl_str_mv Brazilian Journal of Medical and Biological Research v.34 n.5 2001
reponame:Brazilian Journal of Medical and Biological Research
instname:Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
instname_str Associação Brasileira de Divulgação Científica (ABDC)
instacron_str ABDC
institution ABDC
reponame_str Brazilian Journal of Medical and Biological Research
collection Brazilian Journal of Medical and Biological Research
repository.name.fl_str_mv Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)
repository.mail.fl_str_mv bjournal@terra.com.br||bjournal@terra.com.br
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