Plasma and testicular testosterone levels, volume density and number of Leydig cells and spermatogenic efficiency of rabbits
Autor(a) principal: | |
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Data de Publicação: | 2002 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Medical and Biological Research |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000400014 |
Resumo: | Plasma and tissue testosterone concentrations were determined by radioimmunoassay in 12 eight-month-old sexually mature New Zealand White rabbits and evaluated for possible associations with spermatogenic efficiency as well as with volume density and number of Leydig cells. Testicular tissue was processed histologically and histometry was performed in order to quantify germ cells, Sertoli cells and Leydig cells. Spermatogenic efficiency, reported as the ratios among germ cells (spermatogonia, primary spermatocytes and round spermatids) and by the ratio of germ cells to Sertoli cells, was not associated with testosterone levels. However, Leydig cell parameters such as number of Leydig cells per gram of testis, total number of Leydig cells per testis and percent cell volume of Leydig cell nuclei were correlated significantly with testosterone levels. The statistically significant correlation (r = 0.82, P<0.05) observed between testosterone levels and the number of Leydig cells per gram of testis suggests that, in the rabbit, the latter parameter can serve as a criterion for monitoring testosterone levels in this species under normal conditions. |
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Brazilian Journal of Medical and Biological Research |
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Plasma and testicular testosterone levels, volume density and number of Leydig cells and spermatogenic efficiency of rabbitsRabbitTestosteroneLeydig cellSpermatogenesisHistometryPlasma and tissue testosterone concentrations were determined by radioimmunoassay in 12 eight-month-old sexually mature New Zealand White rabbits and evaluated for possible associations with spermatogenic efficiency as well as with volume density and number of Leydig cells. Testicular tissue was processed histologically and histometry was performed in order to quantify germ cells, Sertoli cells and Leydig cells. Spermatogenic efficiency, reported as the ratios among germ cells (spermatogonia, primary spermatocytes and round spermatids) and by the ratio of germ cells to Sertoli cells, was not associated with testosterone levels. However, Leydig cell parameters such as number of Leydig cells per gram of testis, total number of Leydig cells per testis and percent cell volume of Leydig cell nuclei were correlated significantly with testosterone levels. The statistically significant correlation (r = 0.82, P<0.05) observed between testosterone levels and the number of Leydig cells per gram of testis suggests that, in the rabbit, the latter parameter can serve as a criterion for monitoring testosterone levels in this species under normal conditions.Associação Brasileira de Divulgação Científica2002-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000400014Brazilian Journal of Medical and Biological Research v.35 n.4 2002reponame:Brazilian Journal of Medical and Biological Researchinstname:Associação Brasileira de Divulgação Científica (ABDC)instacron:ABDC10.1590/S0100-879X2002000400014info:eu-repo/semantics/openAccessCastro,A.C.S.Berndtson,W.E.Cardoso,F.M.eng2002-04-09T00:00:00Zoai:scielo:S0100-879X2002000400014Revistahttps://www.bjournal.org/https://old.scielo.br/oai/scielo-oai.phpbjournal@terra.com.br||bjournal@terra.com.br1414-431X0100-879Xopendoar:2002-04-09T00:00Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)false |
dc.title.none.fl_str_mv |
Plasma and testicular testosterone levels, volume density and number of Leydig cells and spermatogenic efficiency of rabbits |
title |
Plasma and testicular testosterone levels, volume density and number of Leydig cells and spermatogenic efficiency of rabbits |
spellingShingle |
Plasma and testicular testosterone levels, volume density and number of Leydig cells and spermatogenic efficiency of rabbits Castro,A.C.S. Rabbit Testosterone Leydig cell Spermatogenesis Histometry |
title_short |
Plasma and testicular testosterone levels, volume density and number of Leydig cells and spermatogenic efficiency of rabbits |
title_full |
Plasma and testicular testosterone levels, volume density and number of Leydig cells and spermatogenic efficiency of rabbits |
title_fullStr |
Plasma and testicular testosterone levels, volume density and number of Leydig cells and spermatogenic efficiency of rabbits |
title_full_unstemmed |
Plasma and testicular testosterone levels, volume density and number of Leydig cells and spermatogenic efficiency of rabbits |
title_sort |
Plasma and testicular testosterone levels, volume density and number of Leydig cells and spermatogenic efficiency of rabbits |
author |
Castro,A.C.S. |
author_facet |
Castro,A.C.S. Berndtson,W.E. Cardoso,F.M. |
author_role |
author |
author2 |
Berndtson,W.E. Cardoso,F.M. |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Castro,A.C.S. Berndtson,W.E. Cardoso,F.M. |
dc.subject.por.fl_str_mv |
Rabbit Testosterone Leydig cell Spermatogenesis Histometry |
topic |
Rabbit Testosterone Leydig cell Spermatogenesis Histometry |
description |
Plasma and tissue testosterone concentrations were determined by radioimmunoassay in 12 eight-month-old sexually mature New Zealand White rabbits and evaluated for possible associations with spermatogenic efficiency as well as with volume density and number of Leydig cells. Testicular tissue was processed histologically and histometry was performed in order to quantify germ cells, Sertoli cells and Leydig cells. Spermatogenic efficiency, reported as the ratios among germ cells (spermatogonia, primary spermatocytes and round spermatids) and by the ratio of germ cells to Sertoli cells, was not associated with testosterone levels. However, Leydig cell parameters such as number of Leydig cells per gram of testis, total number of Leydig cells per testis and percent cell volume of Leydig cell nuclei were correlated significantly with testosterone levels. The statistically significant correlation (r = 0.82, P<0.05) observed between testosterone levels and the number of Leydig cells per gram of testis suggests that, in the rabbit, the latter parameter can serve as a criterion for monitoring testosterone levels in this species under normal conditions. |
publishDate |
2002 |
dc.date.none.fl_str_mv |
2002-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000400014 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000400014 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0100-879X2002000400014 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
dc.source.none.fl_str_mv |
Brazilian Journal of Medical and Biological Research v.35 n.4 2002 reponame:Brazilian Journal of Medical and Biological Research instname:Associação Brasileira de Divulgação Científica (ABDC) instacron:ABDC |
instname_str |
Associação Brasileira de Divulgação Científica (ABDC) |
instacron_str |
ABDC |
institution |
ABDC |
reponame_str |
Brazilian Journal of Medical and Biological Research |
collection |
Brazilian Journal of Medical and Biological Research |
repository.name.fl_str_mv |
Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC) |
repository.mail.fl_str_mv |
bjournal@terra.com.br||bjournal@terra.com.br |
_version_ |
1754302931673284608 |