The effect of some processing conditions on the characteristics of biodegradable microspheres obtained by an emulsion solvent evaporation process

Detalhes bibliográficos
Autor(a) principal: Maia,J. L.
Data de Publicação: 2004
Outros Autores: Santana,M. H. A., Ré,M. I.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Chemical Engineering
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322004000100002
Resumo: Unloaded microspheres were prepared from polyhydroxybutyrate (PHB) and polyhydroxybutyrate-co-valerate (PHB-HV) polymers using an oil-in-water emulsion solvent evaporation method. The study was conducted to evaluate how the polymer and some process parameters affect properties of the final microspheres such as particle size, superficial area, zeta potential, surface morphology and microsphere degradation. The variables included surfactant concentration in the emulsion water phase and solvent composition. From the results, it was found that the parameters affecting microsphere size the most were surfactant concentration in the emulsion water phase and solvent composition. Properties such as zeta potential, surface area and surface morphology remained pratically unchanged over the range of the processing conditions studied here.
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spelling The effect of some processing conditions on the characteristics of biodegradable microspheres obtained by an emulsion solvent evaporation processmicroencapsulationpoly-hydroxybutirate-hydroxyvalerateemulsification/evaporationUnloaded microspheres were prepared from polyhydroxybutyrate (PHB) and polyhydroxybutyrate-co-valerate (PHB-HV) polymers using an oil-in-water emulsion solvent evaporation method. The study was conducted to evaluate how the polymer and some process parameters affect properties of the final microspheres such as particle size, superficial area, zeta potential, surface morphology and microsphere degradation. The variables included surfactant concentration in the emulsion water phase and solvent composition. From the results, it was found that the parameters affecting microsphere size the most were surfactant concentration in the emulsion water phase and solvent composition. Properties such as zeta potential, surface area and surface morphology remained pratically unchanged over the range of the processing conditions studied here.Brazilian Society of Chemical Engineering2004-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322004000100002Brazilian Journal of Chemical Engineering v.21 n.1 2004reponame:Brazilian Journal of Chemical Engineeringinstname:Associação Brasileira de Engenharia Química (ABEQ)instacron:ABEQ10.1590/S0104-66322004000100002info:eu-repo/semantics/openAccessMaia,J. L.Santana,M. H. A.Ré,M. I.eng2004-01-14T00:00:00Zoai:scielo:S0104-66322004000100002Revistahttps://www.scielo.br/j/bjce/https://old.scielo.br/oai/scielo-oai.phprgiudici@usp.br||rgiudici@usp.br1678-43830104-6632opendoar:2004-01-14T00:00Brazilian Journal of Chemical Engineering - Associação Brasileira de Engenharia Química (ABEQ)false
dc.title.none.fl_str_mv The effect of some processing conditions on the characteristics of biodegradable microspheres obtained by an emulsion solvent evaporation process
title The effect of some processing conditions on the characteristics of biodegradable microspheres obtained by an emulsion solvent evaporation process
spellingShingle The effect of some processing conditions on the characteristics of biodegradable microspheres obtained by an emulsion solvent evaporation process
Maia,J. L.
microencapsulation
poly-hydroxybutirate-hydroxyvalerate
emulsification/evaporation
title_short The effect of some processing conditions on the characteristics of biodegradable microspheres obtained by an emulsion solvent evaporation process
title_full The effect of some processing conditions on the characteristics of biodegradable microspheres obtained by an emulsion solvent evaporation process
title_fullStr The effect of some processing conditions on the characteristics of biodegradable microspheres obtained by an emulsion solvent evaporation process
title_full_unstemmed The effect of some processing conditions on the characteristics of biodegradable microspheres obtained by an emulsion solvent evaporation process
title_sort The effect of some processing conditions on the characteristics of biodegradable microspheres obtained by an emulsion solvent evaporation process
author Maia,J. L.
author_facet Maia,J. L.
Santana,M. H. A.
Ré,M. I.
author_role author
author2 Santana,M. H. A.
Ré,M. I.
author2_role author
author
dc.contributor.author.fl_str_mv Maia,J. L.
Santana,M. H. A.
Ré,M. I.
dc.subject.por.fl_str_mv microencapsulation
poly-hydroxybutirate-hydroxyvalerate
emulsification/evaporation
topic microencapsulation
poly-hydroxybutirate-hydroxyvalerate
emulsification/evaporation
description Unloaded microspheres were prepared from polyhydroxybutyrate (PHB) and polyhydroxybutyrate-co-valerate (PHB-HV) polymers using an oil-in-water emulsion solvent evaporation method. The study was conducted to evaluate how the polymer and some process parameters affect properties of the final microspheres such as particle size, superficial area, zeta potential, surface morphology and microsphere degradation. The variables included surfactant concentration in the emulsion water phase and solvent composition. From the results, it was found that the parameters affecting microsphere size the most were surfactant concentration in the emulsion water phase and solvent composition. Properties such as zeta potential, surface area and surface morphology remained pratically unchanged over the range of the processing conditions studied here.
publishDate 2004
dc.date.none.fl_str_mv 2004-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322004000100002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322004000100002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0104-66322004000100002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Brazilian Society of Chemical Engineering
publisher.none.fl_str_mv Brazilian Society of Chemical Engineering
dc.source.none.fl_str_mv Brazilian Journal of Chemical Engineering v.21 n.1 2004
reponame:Brazilian Journal of Chemical Engineering
instname:Associação Brasileira de Engenharia Química (ABEQ)
instacron:ABEQ
instname_str Associação Brasileira de Engenharia Química (ABEQ)
instacron_str ABEQ
institution ABEQ
reponame_str Brazilian Journal of Chemical Engineering
collection Brazilian Journal of Chemical Engineering
repository.name.fl_str_mv Brazilian Journal of Chemical Engineering - Associação Brasileira de Engenharia Química (ABEQ)
repository.mail.fl_str_mv rgiudici@usp.br||rgiudici@usp.br
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