Mediastinal nonleukemic granulocytic sarcoma with cardiac infiltration

Detalhes bibliográficos
Autor(a) principal: Lima,Gabrielle G.
Data de Publicação: 2008
Outros Autores: Rocha Filho,Francisco D., Ferreira,Francisco V. A., Linhares,Bruno L., Pereira,Viviane C., Freitas,Helano C.
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Revista brasileira de hematologia e hemoterapia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842008000400022
Resumo: We report on a case of mediastinal granulocytic sarcoma with cardiac infiltration in a young man with no evidence of leukemia involving the bone marrow or peripheral blood. Diagnosis was accomplished by immuno-histochemistry with expressions of myeloperoxidase and CD99 antigens. The patient achieved clinical remission, but evolved with febrile neutropenia during chemotherapy and died. Although subclinical cardiac infiltrations are commonly found at autopsy in patients with acute non-lymphoblastic leukemia, only one case of involvement of the heart with granulocytic sarcoma in the absence of bone marrow disease has been published in the literature. A diagnosis of granulocytic sarcoma should not be excluded when the biopsy of the bone marrow does not show any evidence of leukemic infiltration.
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spelling Mediastinal nonleukemic granulocytic sarcoma with cardiac infiltrationGranulocytic sarcomaleukemiacardiac infiltrationWe report on a case of mediastinal granulocytic sarcoma with cardiac infiltration in a young man with no evidence of leukemia involving the bone marrow or peripheral blood. Diagnosis was accomplished by immuno-histochemistry with expressions of myeloperoxidase and CD99 antigens. The patient achieved clinical remission, but evolved with febrile neutropenia during chemotherapy and died. Although subclinical cardiac infiltrations are commonly found at autopsy in patients with acute non-lymphoblastic leukemia, only one case of involvement of the heart with granulocytic sarcoma in the absence of bone marrow disease has been published in the literature. A diagnosis of granulocytic sarcoma should not be excluded when the biopsy of the bone marrow does not show any evidence of leukemic infiltration.Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular2008-08-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842008000400022Revista Brasileira de Hematologia e Hemoterapia v.30 n.4 2008reponame:Revista brasileira de hematologia e hemoterapia (Online)instname:Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)instacron:ABHHTC10.1590/S1516-84842008000400022info:eu-repo/semantics/openAccessLima,Gabrielle G.Rocha Filho,Francisco D.Ferreira,Francisco V. A.Linhares,Bruno L.Pereira,Viviane C.Freitas,Helano C.eng2008-10-28T00:00:00Zoai:scielo:S1516-84842008000400022Revistahttp://www.rbhh.org/pt/archivo/https://old.scielo.br/oai/scielo-oai.phpsbhh@terra.com.br||secretaria@rbhh.org1806-08701516-8484opendoar:2008-10-28T00:00Revista brasileira de hematologia e hemoterapia (Online) - Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)false
dc.title.none.fl_str_mv Mediastinal nonleukemic granulocytic sarcoma with cardiac infiltration
title Mediastinal nonleukemic granulocytic sarcoma with cardiac infiltration
spellingShingle Mediastinal nonleukemic granulocytic sarcoma with cardiac infiltration
Lima,Gabrielle G.
Granulocytic sarcoma
leukemia
cardiac infiltration
title_short Mediastinal nonleukemic granulocytic sarcoma with cardiac infiltration
title_full Mediastinal nonleukemic granulocytic sarcoma with cardiac infiltration
title_fullStr Mediastinal nonleukemic granulocytic sarcoma with cardiac infiltration
title_full_unstemmed Mediastinal nonleukemic granulocytic sarcoma with cardiac infiltration
title_sort Mediastinal nonleukemic granulocytic sarcoma with cardiac infiltration
author Lima,Gabrielle G.
author_facet Lima,Gabrielle G.
Rocha Filho,Francisco D.
Ferreira,Francisco V. A.
Linhares,Bruno L.
Pereira,Viviane C.
Freitas,Helano C.
author_role author
author2 Rocha Filho,Francisco D.
Ferreira,Francisco V. A.
Linhares,Bruno L.
Pereira,Viviane C.
Freitas,Helano C.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Lima,Gabrielle G.
Rocha Filho,Francisco D.
Ferreira,Francisco V. A.
Linhares,Bruno L.
Pereira,Viviane C.
Freitas,Helano C.
dc.subject.por.fl_str_mv Granulocytic sarcoma
leukemia
cardiac infiltration
topic Granulocytic sarcoma
leukemia
cardiac infiltration
description We report on a case of mediastinal granulocytic sarcoma with cardiac infiltration in a young man with no evidence of leukemia involving the bone marrow or peripheral blood. Diagnosis was accomplished by immuno-histochemistry with expressions of myeloperoxidase and CD99 antigens. The patient achieved clinical remission, but evolved with febrile neutropenia during chemotherapy and died. Although subclinical cardiac infiltrations are commonly found at autopsy in patients with acute non-lymphoblastic leukemia, only one case of involvement of the heart with granulocytic sarcoma in the absence of bone marrow disease has been published in the literature. A diagnosis of granulocytic sarcoma should not be excluded when the biopsy of the bone marrow does not show any evidence of leukemic infiltration.
publishDate 2008
dc.date.none.fl_str_mv 2008-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842008000400022
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842008000400022
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-84842008000400022
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular
publisher.none.fl_str_mv Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular
dc.source.none.fl_str_mv Revista Brasileira de Hematologia e Hemoterapia v.30 n.4 2008
reponame:Revista brasileira de hematologia e hemoterapia (Online)
instname:Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)
instacron:ABHHTC
instname_str Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)
instacron_str ABHHTC
institution ABHHTC
reponame_str Revista brasileira de hematologia e hemoterapia (Online)
collection Revista brasileira de hematologia e hemoterapia (Online)
repository.name.fl_str_mv Revista brasileira de hematologia e hemoterapia (Online) - Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)
repository.mail.fl_str_mv sbhh@terra.com.br||secretaria@rbhh.org
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