Effect of sterilization on the properties of CDHA-OCP-beta-TCP biomaterial

Detalhes bibliográficos
Autor(a) principal: Morejón-Alonso,Loreley
Data de Publicação: 2007
Outros Autores: Carrodeguas,Raúl García, García-Menocal,José Ángel Delgado, Pérez,José Antonio Alonso, Manent,Salvador Martínez
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Materials research (São Carlos. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392007000100005
Resumo: The effect of the method of sterilization on the physical, chemical and mechanical properties of a new bone repairing material was studied. The material was obtained by thermal hydrolysis of beta-tricalcium phosphate/orthophosphoric acid cement and was composed of calcium deficient hydroxyapatite, octacalcium phosphate (OCP), and beta-tricalcium phosphate. Partial decomposition of the OCP was observed after sterilization for the three methods. Decomposition increased to the following sequence of sterilization methods: ethylene oxide; autoclaving; dry oven. On the other hand, mechanical strength decreased with regard to non sterilized material in the sterilization sequence: ethylene oxide; dry oven; autoclaving. The compressive strength was 8.5 ± 1.0; 9.0 ± 1.2; 8.2 ± 0.8 and 6.5 ± 1.0 MPa, whereas diametral tensile strength was 2.1 ± 0.3; 2.5 ± 0.1; 1.9 ± 0.9 and 1.6 ± 0.3 for the material sterilized by ethylene oxide, dry oven, and autoclaving, respectively. Several compositional and microstuctural changes were detected after dry heat and autoclave sterilization. Ethylene oxide sterilization had lesser effect on the chemical composition and strength than dry heat and autoclaving.
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spelling Effect of sterilization on the properties of CDHA-OCP-beta-TCP biomaterialoctacalcium phosphatecalcium-deficient hydroxiapatitetricalcium phosphatesterilizationThe effect of the method of sterilization on the physical, chemical and mechanical properties of a new bone repairing material was studied. The material was obtained by thermal hydrolysis of beta-tricalcium phosphate/orthophosphoric acid cement and was composed of calcium deficient hydroxyapatite, octacalcium phosphate (OCP), and beta-tricalcium phosphate. Partial decomposition of the OCP was observed after sterilization for the three methods. Decomposition increased to the following sequence of sterilization methods: ethylene oxide; autoclaving; dry oven. On the other hand, mechanical strength decreased with regard to non sterilized material in the sterilization sequence: ethylene oxide; dry oven; autoclaving. The compressive strength was 8.5 ± 1.0; 9.0 ± 1.2; 8.2 ± 0.8 and 6.5 ± 1.0 MPa, whereas diametral tensile strength was 2.1 ± 0.3; 2.5 ± 0.1; 1.9 ± 0.9 and 1.6 ± 0.3 for the material sterilized by ethylene oxide, dry oven, and autoclaving, respectively. Several compositional and microstuctural changes were detected after dry heat and autoclave sterilization. Ethylene oxide sterilization had lesser effect on the chemical composition and strength than dry heat and autoclaving.ABM, ABC, ABPol2007-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392007000100005Materials Research v.10 n.1 2007reponame:Materials research (São Carlos. Online)instname:Universidade Federal de São Carlos (UFSCAR)instacron:ABM ABC ABPOL10.1590/S1516-14392007000100005info:eu-repo/semantics/openAccessMorejón-Alonso,LoreleyCarrodeguas,Raúl GarcíaGarcía-Menocal,José Ángel DelgadoPérez,José Antonio AlonsoManent,Salvador Martínezeng2007-05-03T00:00:00Zoai:scielo:S1516-14392007000100005Revistahttp://www.scielo.br/mrPUBhttps://old.scielo.br/oai/scielo-oai.phpdedz@power.ufscar.br1980-53731516-1439opendoar:2007-05-03T00:00Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)false
dc.title.none.fl_str_mv Effect of sterilization on the properties of CDHA-OCP-beta-TCP biomaterial
title Effect of sterilization on the properties of CDHA-OCP-beta-TCP biomaterial
spellingShingle Effect of sterilization on the properties of CDHA-OCP-beta-TCP biomaterial
Morejón-Alonso,Loreley
octacalcium phosphate
calcium-deficient hydroxiapatite
tricalcium phosphate
sterilization
title_short Effect of sterilization on the properties of CDHA-OCP-beta-TCP biomaterial
title_full Effect of sterilization on the properties of CDHA-OCP-beta-TCP biomaterial
title_fullStr Effect of sterilization on the properties of CDHA-OCP-beta-TCP biomaterial
title_full_unstemmed Effect of sterilization on the properties of CDHA-OCP-beta-TCP biomaterial
title_sort Effect of sterilization on the properties of CDHA-OCP-beta-TCP biomaterial
author Morejón-Alonso,Loreley
author_facet Morejón-Alonso,Loreley
Carrodeguas,Raúl García
García-Menocal,José Ángel Delgado
Pérez,José Antonio Alonso
Manent,Salvador Martínez
author_role author
author2 Carrodeguas,Raúl García
García-Menocal,José Ángel Delgado
Pérez,José Antonio Alonso
Manent,Salvador Martínez
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Morejón-Alonso,Loreley
Carrodeguas,Raúl García
García-Menocal,José Ángel Delgado
Pérez,José Antonio Alonso
Manent,Salvador Martínez
dc.subject.por.fl_str_mv octacalcium phosphate
calcium-deficient hydroxiapatite
tricalcium phosphate
sterilization
topic octacalcium phosphate
calcium-deficient hydroxiapatite
tricalcium phosphate
sterilization
description The effect of the method of sterilization on the physical, chemical and mechanical properties of a new bone repairing material was studied. The material was obtained by thermal hydrolysis of beta-tricalcium phosphate/orthophosphoric acid cement and was composed of calcium deficient hydroxyapatite, octacalcium phosphate (OCP), and beta-tricalcium phosphate. Partial decomposition of the OCP was observed after sterilization for the three methods. Decomposition increased to the following sequence of sterilization methods: ethylene oxide; autoclaving; dry oven. On the other hand, mechanical strength decreased with regard to non sterilized material in the sterilization sequence: ethylene oxide; dry oven; autoclaving. The compressive strength was 8.5 ± 1.0; 9.0 ± 1.2; 8.2 ± 0.8 and 6.5 ± 1.0 MPa, whereas diametral tensile strength was 2.1 ± 0.3; 2.5 ± 0.1; 1.9 ± 0.9 and 1.6 ± 0.3 for the material sterilized by ethylene oxide, dry oven, and autoclaving, respectively. Several compositional and microstuctural changes were detected after dry heat and autoclave sterilization. Ethylene oxide sterilization had lesser effect on the chemical composition and strength than dry heat and autoclaving.
publishDate 2007
dc.date.none.fl_str_mv 2007-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392007000100005
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392007000100005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-14392007000100005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv ABM, ABC, ABPol
publisher.none.fl_str_mv ABM, ABC, ABPol
dc.source.none.fl_str_mv Materials Research v.10 n.1 2007
reponame:Materials research (São Carlos. Online)
instname:Universidade Federal de São Carlos (UFSCAR)
instacron:ABM ABC ABPOL
instname_str Universidade Federal de São Carlos (UFSCAR)
instacron_str ABM ABC ABPOL
institution ABM ABC ABPOL
reponame_str Materials research (São Carlos. Online)
collection Materials research (São Carlos. Online)
repository.name.fl_str_mv Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)
repository.mail.fl_str_mv dedz@power.ufscar.br
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