Metallic ions in organs of rats injected with metallic particles of stainless steel 316L and Ti6Al4V alloy

Bibliographic Details
Main Author: Giertz,Silvia Helena
Publication Date: 2010
Other Authors: Fernandes,Beatriz Luci, Fernandes,Carlos Roberto, Franco,Celia Regina Cavichiolo
Format: Article
Language: eng
Source: Materials research (São Carlos. Online)
Download full: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392010000100009
Summary: Despite the interest in identifying systemic effects caused by the metallic particles released from long term metallic implants in the body, few works support reliable conclusions about the effects of those particles in organs. The aim of the present work is to look for damages in tissues of liver, kidney, lung and heart of rats submitted to injection of Hank's solution contained particles of Ti6Al4V alloy and Stainless Steel 316L, obtained by metal friction. The particles size ranges from 50 to 200 µm for the Ti alloy and from 100 to 500 µm for the 316L. Tissues isolated from the organs after the euthanasia were prepared and analyzed in an optical microscope and Energy Dispersive Spectrometer (EDS). Lesions caused by an inflammatory response such as strange body epithelioid granuloma and giant cells were found in some of the tissues containing yttrium and aluminum.
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spelling Metallic ions in organs of rats injected with metallic particles of stainless steel 316L and Ti6Al4V alloymetallic implantsparticles releasein vivo testTi6Al4V alloystainless steel 316LDespite the interest in identifying systemic effects caused by the metallic particles released from long term metallic implants in the body, few works support reliable conclusions about the effects of those particles in organs. The aim of the present work is to look for damages in tissues of liver, kidney, lung and heart of rats submitted to injection of Hank's solution contained particles of Ti6Al4V alloy and Stainless Steel 316L, obtained by metal friction. The particles size ranges from 50 to 200 µm for the Ti alloy and from 100 to 500 µm for the 316L. Tissues isolated from the organs after the euthanasia were prepared and analyzed in an optical microscope and Energy Dispersive Spectrometer (EDS). Lesions caused by an inflammatory response such as strange body epithelioid granuloma and giant cells were found in some of the tissues containing yttrium and aluminum.ABM, ABC, ABPol2010-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392010000100009Materials Research v.13 n.1 2010reponame:Materials research (São Carlos. Online)instname:Universidade Federal de São Carlos (UFSCAR)instacron:ABM ABC ABPOL10.1590/S1516-14392010000100009info:eu-repo/semantics/openAccessGiertz,Silvia HelenaFernandes,Beatriz LuciFernandes,Carlos RobertoFranco,Celia Regina Cavichioloeng2010-04-13T00:00:00Zoai:scielo:S1516-14392010000100009Revistahttp://www.scielo.br/mrPUBhttps://old.scielo.br/oai/scielo-oai.phpdedz@power.ufscar.br1980-53731516-1439opendoar:2010-04-13T00:00Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)false
dc.title.none.fl_str_mv Metallic ions in organs of rats injected with metallic particles of stainless steel 316L and Ti6Al4V alloy
title Metallic ions in organs of rats injected with metallic particles of stainless steel 316L and Ti6Al4V alloy
spellingShingle Metallic ions in organs of rats injected with metallic particles of stainless steel 316L and Ti6Al4V alloy
Giertz,Silvia Helena
metallic implants
particles release
in vivo test
Ti6Al4V alloy
stainless steel 316L
title_short Metallic ions in organs of rats injected with metallic particles of stainless steel 316L and Ti6Al4V alloy
title_full Metallic ions in organs of rats injected with metallic particles of stainless steel 316L and Ti6Al4V alloy
title_fullStr Metallic ions in organs of rats injected with metallic particles of stainless steel 316L and Ti6Al4V alloy
title_full_unstemmed Metallic ions in organs of rats injected with metallic particles of stainless steel 316L and Ti6Al4V alloy
title_sort Metallic ions in organs of rats injected with metallic particles of stainless steel 316L and Ti6Al4V alloy
author Giertz,Silvia Helena
author_facet Giertz,Silvia Helena
Fernandes,Beatriz Luci
Fernandes,Carlos Roberto
Franco,Celia Regina Cavichiolo
author_role author
author2 Fernandes,Beatriz Luci
Fernandes,Carlos Roberto
Franco,Celia Regina Cavichiolo
author2_role author
author
author
dc.contributor.author.fl_str_mv Giertz,Silvia Helena
Fernandes,Beatriz Luci
Fernandes,Carlos Roberto
Franco,Celia Regina Cavichiolo
dc.subject.por.fl_str_mv metallic implants
particles release
in vivo test
Ti6Al4V alloy
stainless steel 316L
topic metallic implants
particles release
in vivo test
Ti6Al4V alloy
stainless steel 316L
description Despite the interest in identifying systemic effects caused by the metallic particles released from long term metallic implants in the body, few works support reliable conclusions about the effects of those particles in organs. The aim of the present work is to look for damages in tissues of liver, kidney, lung and heart of rats submitted to injection of Hank's solution contained particles of Ti6Al4V alloy and Stainless Steel 316L, obtained by metal friction. The particles size ranges from 50 to 200 µm for the Ti alloy and from 100 to 500 µm for the 316L. Tissues isolated from the organs after the euthanasia were prepared and analyzed in an optical microscope and Energy Dispersive Spectrometer (EDS). Lesions caused by an inflammatory response such as strange body epithelioid granuloma and giant cells were found in some of the tissues containing yttrium and aluminum.
publishDate 2010
dc.date.none.fl_str_mv 2010-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392010000100009
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392010000100009
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-14392010000100009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv ABM, ABC, ABPol
publisher.none.fl_str_mv ABM, ABC, ABPol
dc.source.none.fl_str_mv Materials Research v.13 n.1 2010
reponame:Materials research (São Carlos. Online)
instname:Universidade Federal de São Carlos (UFSCAR)
instacron:ABM ABC ABPOL
instname_str Universidade Federal de São Carlos (UFSCAR)
instacron_str ABM ABC ABPOL
institution ABM ABC ABPOL
reponame_str Materials research (São Carlos. Online)
collection Materials research (São Carlos. Online)
repository.name.fl_str_mv Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)
repository.mail.fl_str_mv dedz@power.ufscar.br
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