Calcium phosphate submicrometric fibers produced by solution blow spinning
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Materials research (São Carlos. Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392019000300219 |
Resumo: | The purpose of this work was to produce submicrometric hydroxyapatite (HA) and beta-tricalcium phosphate (β-TCP) biphasic fibers by means of solution blow spinning (SBS). This method was chosen due to its lower cost and higher production rate than those of electrospinning, which is normally employed in ceramic fiber production. The fibers thus obtained were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and thermogravimetric analysis (TGA). The in vitro bioactivity and cytotoxicity of the fibers were also investigated. The XRD patterns indicated the formation of biphasic HA/βTCP fibers. SEM analysis revealed an interconnected cylindrical morphology with the presence of beads. Fiber diameters in the submicrometric range varied from 374 to 451 nm. TGA results indicated that organic losses occurred solely below 600ºC. All the fibers were non-cytotoxic, presenting an inhibitory concentration (IC) of > IC50. All the samples successfully formed acicular apatite layers when immersed in SBF, indicating a high potential for in vivo bone bioactivity. |
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Calcium phosphate submicrometric fibers produced by solution blow spinningCalcium phosphatenanofiberssolution blow spinningThe purpose of this work was to produce submicrometric hydroxyapatite (HA) and beta-tricalcium phosphate (β-TCP) biphasic fibers by means of solution blow spinning (SBS). This method was chosen due to its lower cost and higher production rate than those of electrospinning, which is normally employed in ceramic fiber production. The fibers thus obtained were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and thermogravimetric analysis (TGA). The in vitro bioactivity and cytotoxicity of the fibers were also investigated. The XRD patterns indicated the formation of biphasic HA/βTCP fibers. SEM analysis revealed an interconnected cylindrical morphology with the presence of beads. Fiber diameters in the submicrometric range varied from 374 to 451 nm. TGA results indicated that organic losses occurred solely below 600ºC. All the fibers were non-cytotoxic, presenting an inhibitory concentration (IC) of > IC50. All the samples successfully formed acicular apatite layers when immersed in SBF, indicating a high potential for in vivo bone bioactivity.ABM, ABC, ABPol2019-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392019000300219Materials Research v.22 n.3 2019reponame:Materials research (São Carlos. Online)instname:Universidade Federal de São Carlos (UFSCAR)instacron:ABM ABC ABPOL10.1590/1980-5373-mr-2018-0753info:eu-repo/semantics/openAccessOliveira,Matheus José Cunha deBonan,Roberta FerretiCampos,Samara GomesNeves,Gelmires de AraújoMenezes,Romualdo Rodrigueseng2019-04-16T00:00:00Zoai:scielo:S1516-14392019000300219Revistahttp://www.scielo.br/mrPUBhttps://old.scielo.br/oai/scielo-oai.phpdedz@power.ufscar.br1980-53731516-1439opendoar:2019-04-16T00:00Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)false |
dc.title.none.fl_str_mv |
Calcium phosphate submicrometric fibers produced by solution blow spinning |
title |
Calcium phosphate submicrometric fibers produced by solution blow spinning |
spellingShingle |
Calcium phosphate submicrometric fibers produced by solution blow spinning Oliveira,Matheus José Cunha de Calcium phosphate nanofibers solution blow spinning |
title_short |
Calcium phosphate submicrometric fibers produced by solution blow spinning |
title_full |
Calcium phosphate submicrometric fibers produced by solution blow spinning |
title_fullStr |
Calcium phosphate submicrometric fibers produced by solution blow spinning |
title_full_unstemmed |
Calcium phosphate submicrometric fibers produced by solution blow spinning |
title_sort |
Calcium phosphate submicrometric fibers produced by solution blow spinning |
author |
Oliveira,Matheus José Cunha de |
author_facet |
Oliveira,Matheus José Cunha de Bonan,Roberta Ferreti Campos,Samara Gomes Neves,Gelmires de Araújo Menezes,Romualdo Rodrigues |
author_role |
author |
author2 |
Bonan,Roberta Ferreti Campos,Samara Gomes Neves,Gelmires de Araújo Menezes,Romualdo Rodrigues |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Oliveira,Matheus José Cunha de Bonan,Roberta Ferreti Campos,Samara Gomes Neves,Gelmires de Araújo Menezes,Romualdo Rodrigues |
dc.subject.por.fl_str_mv |
Calcium phosphate nanofibers solution blow spinning |
topic |
Calcium phosphate nanofibers solution blow spinning |
description |
The purpose of this work was to produce submicrometric hydroxyapatite (HA) and beta-tricalcium phosphate (β-TCP) biphasic fibers by means of solution blow spinning (SBS). This method was chosen due to its lower cost and higher production rate than those of electrospinning, which is normally employed in ceramic fiber production. The fibers thus obtained were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and thermogravimetric analysis (TGA). The in vitro bioactivity and cytotoxicity of the fibers were also investigated. The XRD patterns indicated the formation of biphasic HA/βTCP fibers. SEM analysis revealed an interconnected cylindrical morphology with the presence of beads. Fiber diameters in the submicrometric range varied from 374 to 451 nm. TGA results indicated that organic losses occurred solely below 600ºC. All the fibers were non-cytotoxic, presenting an inhibitory concentration (IC) of > IC50. All the samples successfully formed acicular apatite layers when immersed in SBF, indicating a high potential for in vivo bone bioactivity. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392019000300219 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392019000300219 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1980-5373-mr-2018-0753 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
ABM, ABC, ABPol |
publisher.none.fl_str_mv |
ABM, ABC, ABPol |
dc.source.none.fl_str_mv |
Materials Research v.22 n.3 2019 reponame:Materials research (São Carlos. Online) instname:Universidade Federal de São Carlos (UFSCAR) instacron:ABM ABC ABPOL |
instname_str |
Universidade Federal de São Carlos (UFSCAR) |
instacron_str |
ABM ABC ABPOL |
institution |
ABM ABC ABPOL |
reponame_str |
Materials research (São Carlos. Online) |
collection |
Materials research (São Carlos. Online) |
repository.name.fl_str_mv |
Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR) |
repository.mail.fl_str_mv |
dedz@power.ufscar.br |
_version_ |
1754212674759032832 |