Effects of virtual reality therapy on upper limb function after stroke and the role of neuroimaging as a predictor of a better response

Detalhes bibliográficos
Autor(a) principal: Gonçalves,Maicon Gabriel
Data de Publicação: 2018
Outros Autores: Piva,Mariana Floriano Luiza, Marques,Carlos Leonardo Sacomani, Costa,Rafael Dalle Molle da, Bazan,Rodrigo, Luvizutto,Gustavo José, Betting,Luiz Eduardo Gomes Garcia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018001000654
Resumo: ABSTRACT Background: Virtual reality therapy (VRT) is an interactive intervention that induces neuroplasticity. The aim was to evaluate the effects of VRT associated with conventional rehabilitation for an upper limb after stroke, and the neuroimaging predictors of a better response to VRT. Methods: Patients with stroke were selected, and clinical neurological, upper limb function, and quality of life were evaluated. Statistical analysis was performed using a linear model comparing pre- and post-VRT. Lesions were segmented in the post-stroke computed tomography. A voxel-based lesion-symptom mapping approach was used to investigate the relationship between the lesion and upper limb function. Results: Eighteen patients were studied (55.5 ± 13.9 years of age). Quality of life, functional independence, and dexterity of the upper limb showed improvement after VRT (p < 0.001). Neuroimaging analysis showed negative correlations between the internal capsule lesion and functional recovery. Conclusion: VRT showed benefits for patients with stroke, but when there was an internal capsule lesion, a worse response was observed.
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spelling Effects of virtual reality therapy on upper limb function after stroke and the role of neuroimaging as a predictor of a better responseStrokeneuroimagingvirtual reality exposure therapyABSTRACT Background: Virtual reality therapy (VRT) is an interactive intervention that induces neuroplasticity. The aim was to evaluate the effects of VRT associated with conventional rehabilitation for an upper limb after stroke, and the neuroimaging predictors of a better response to VRT. Methods: Patients with stroke were selected, and clinical neurological, upper limb function, and quality of life were evaluated. Statistical analysis was performed using a linear model comparing pre- and post-VRT. Lesions were segmented in the post-stroke computed tomography. A voxel-based lesion-symptom mapping approach was used to investigate the relationship between the lesion and upper limb function. Results: Eighteen patients were studied (55.5 ± 13.9 years of age). Quality of life, functional independence, and dexterity of the upper limb showed improvement after VRT (p < 0.001). Neuroimaging analysis showed negative correlations between the internal capsule lesion and functional recovery. Conclusion: VRT showed benefits for patients with stroke, but when there was an internal capsule lesion, a worse response was observed.Academia Brasileira de Neurologia - ABNEURO2018-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018001000654Arquivos de Neuro-Psiquiatria v.76 n.10 2018reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x20180104info:eu-repo/semantics/openAccessGonçalves,Maicon GabrielPiva,Mariana Floriano LuizaMarques,Carlos Leonardo SacomaniCosta,Rafael Dalle Molle daBazan,RodrigoLuvizutto,Gustavo JoséBetting,Luiz Eduardo Gomes Garciaeng2018-10-29T00:00:00Zoai:scielo:S0004-282X2018001000654Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2018-10-29T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Effects of virtual reality therapy on upper limb function after stroke and the role of neuroimaging as a predictor of a better response
title Effects of virtual reality therapy on upper limb function after stroke and the role of neuroimaging as a predictor of a better response
spellingShingle Effects of virtual reality therapy on upper limb function after stroke and the role of neuroimaging as a predictor of a better response
Gonçalves,Maicon Gabriel
Stroke
neuroimaging
virtual reality exposure therapy
title_short Effects of virtual reality therapy on upper limb function after stroke and the role of neuroimaging as a predictor of a better response
title_full Effects of virtual reality therapy on upper limb function after stroke and the role of neuroimaging as a predictor of a better response
title_fullStr Effects of virtual reality therapy on upper limb function after stroke and the role of neuroimaging as a predictor of a better response
title_full_unstemmed Effects of virtual reality therapy on upper limb function after stroke and the role of neuroimaging as a predictor of a better response
title_sort Effects of virtual reality therapy on upper limb function after stroke and the role of neuroimaging as a predictor of a better response
author Gonçalves,Maicon Gabriel
author_facet Gonçalves,Maicon Gabriel
Piva,Mariana Floriano Luiza
Marques,Carlos Leonardo Sacomani
Costa,Rafael Dalle Molle da
Bazan,Rodrigo
Luvizutto,Gustavo José
Betting,Luiz Eduardo Gomes Garcia
author_role author
author2 Piva,Mariana Floriano Luiza
Marques,Carlos Leonardo Sacomani
Costa,Rafael Dalle Molle da
Bazan,Rodrigo
Luvizutto,Gustavo José
Betting,Luiz Eduardo Gomes Garcia
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gonçalves,Maicon Gabriel
Piva,Mariana Floriano Luiza
Marques,Carlos Leonardo Sacomani
Costa,Rafael Dalle Molle da
Bazan,Rodrigo
Luvizutto,Gustavo José
Betting,Luiz Eduardo Gomes Garcia
dc.subject.por.fl_str_mv Stroke
neuroimaging
virtual reality exposure therapy
topic Stroke
neuroimaging
virtual reality exposure therapy
description ABSTRACT Background: Virtual reality therapy (VRT) is an interactive intervention that induces neuroplasticity. The aim was to evaluate the effects of VRT associated with conventional rehabilitation for an upper limb after stroke, and the neuroimaging predictors of a better response to VRT. Methods: Patients with stroke were selected, and clinical neurological, upper limb function, and quality of life were evaluated. Statistical analysis was performed using a linear model comparing pre- and post-VRT. Lesions were segmented in the post-stroke computed tomography. A voxel-based lesion-symptom mapping approach was used to investigate the relationship between the lesion and upper limb function. Results: Eighteen patients were studied (55.5 ± 13.9 years of age). Quality of life, functional independence, and dexterity of the upper limb showed improvement after VRT (p < 0.001). Neuroimaging analysis showed negative correlations between the internal capsule lesion and functional recovery. Conclusion: VRT showed benefits for patients with stroke, but when there was an internal capsule lesion, a worse response was observed.
publishDate 2018
dc.date.none.fl_str_mv 2018-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018001000654
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0004-282x20180104
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eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.76 n.10 2018
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
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reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
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