Alpha power oscillation in the frontal cortex under Bromazepam and Modafinil effects

Detalhes bibliográficos
Autor(a) principal: Aprigio,Danielle
Data de Publicação: 2015
Outros Autores: Adolfo,Washington, Bittencourt,Juliana, Gongora,Mariana, Teixeira,Silmar, Basile,Luis Fernando, Budde,Henning, Cagy,Mauricio, Ribeiro,Pedro, Velasques,Bruna
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001100918
Resumo: ABSTRACTObjective Our aim was to investigate and compare the neuromodulatory effects of bromazepam (6 mg) and modafinil (200 mg) during a sensorimotor task analyzing the changes produced in the absolute alpha power.Method The sample was composed of 15 healthy individuals exposed to three experimental conditions: placebo, modafinil and bromazepam. EEG data were recorded before, during and after the execution of the task. A three-way ANOVA was applied, in order to compare the absolute alpha power among the factors: Group (control, bromazepam and modafinil) Condition (Pre and Post-drug ingestion) and Moment (pre and post-stimulus).Results Interaction was found between the group and condition factors for Fp1, F4 and F3. We observed a main effect of moment and condition for the Fp2, F8 and Fz electrodes.Conclusion We concluded that drugs may interfere in sensorimotor processes, such as in the performance of tasks carried out in an unpredictable scenario.
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spelling Alpha power oscillation in the frontal cortex under Bromazepam and Modafinil effectselectroencephalographycentral nervous system agentsbrain mappingABSTRACTObjective Our aim was to investigate and compare the neuromodulatory effects of bromazepam (6 mg) and modafinil (200 mg) during a sensorimotor task analyzing the changes produced in the absolute alpha power.Method The sample was composed of 15 healthy individuals exposed to three experimental conditions: placebo, modafinil and bromazepam. EEG data were recorded before, during and after the execution of the task. A three-way ANOVA was applied, in order to compare the absolute alpha power among the factors: Group (control, bromazepam and modafinil) Condition (Pre and Post-drug ingestion) and Moment (pre and post-stimulus).Results Interaction was found between the group and condition factors for Fp1, F4 and F3. We observed a main effect of moment and condition for the Fp2, F8 and Fz electrodes.Conclusion We concluded that drugs may interfere in sensorimotor processes, such as in the performance of tasks carried out in an unpredictable scenario.Academia Brasileira de Neurologia - ABNEURO2015-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001100918Arquivos de Neuro-Psiquiatria v.73 n.11 2015reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282X20150140info:eu-repo/semantics/openAccessAprigio,DanielleAdolfo,WashingtonBittencourt,JulianaGongora,MarianaTeixeira,SilmarBasile,Luis FernandoBudde,HenningCagy,MauricioRibeiro,PedroVelasques,Brunaeng2015-10-22T00:00:00Zoai:scielo:S0004-282X2015001100918Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2015-10-22T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Alpha power oscillation in the frontal cortex under Bromazepam and Modafinil effects
title Alpha power oscillation in the frontal cortex under Bromazepam and Modafinil effects
spellingShingle Alpha power oscillation in the frontal cortex under Bromazepam and Modafinil effects
Aprigio,Danielle
electroencephalography
central nervous system agents
brain mapping
title_short Alpha power oscillation in the frontal cortex under Bromazepam and Modafinil effects
title_full Alpha power oscillation in the frontal cortex under Bromazepam and Modafinil effects
title_fullStr Alpha power oscillation in the frontal cortex under Bromazepam and Modafinil effects
title_full_unstemmed Alpha power oscillation in the frontal cortex under Bromazepam and Modafinil effects
title_sort Alpha power oscillation in the frontal cortex under Bromazepam and Modafinil effects
author Aprigio,Danielle
author_facet Aprigio,Danielle
Adolfo,Washington
Bittencourt,Juliana
Gongora,Mariana
Teixeira,Silmar
Basile,Luis Fernando
Budde,Henning
Cagy,Mauricio
Ribeiro,Pedro
Velasques,Bruna
author_role author
author2 Adolfo,Washington
Bittencourt,Juliana
Gongora,Mariana
Teixeira,Silmar
Basile,Luis Fernando
Budde,Henning
Cagy,Mauricio
Ribeiro,Pedro
Velasques,Bruna
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Aprigio,Danielle
Adolfo,Washington
Bittencourt,Juliana
Gongora,Mariana
Teixeira,Silmar
Basile,Luis Fernando
Budde,Henning
Cagy,Mauricio
Ribeiro,Pedro
Velasques,Bruna
dc.subject.por.fl_str_mv electroencephalography
central nervous system agents
brain mapping
topic electroencephalography
central nervous system agents
brain mapping
description ABSTRACTObjective Our aim was to investigate and compare the neuromodulatory effects of bromazepam (6 mg) and modafinil (200 mg) during a sensorimotor task analyzing the changes produced in the absolute alpha power.Method The sample was composed of 15 healthy individuals exposed to three experimental conditions: placebo, modafinil and bromazepam. EEG data were recorded before, during and after the execution of the task. A three-way ANOVA was applied, in order to compare the absolute alpha power among the factors: Group (control, bromazepam and modafinil) Condition (Pre and Post-drug ingestion) and Moment (pre and post-stimulus).Results Interaction was found between the group and condition factors for Fp1, F4 and F3. We observed a main effect of moment and condition for the Fp2, F8 and Fz electrodes.Conclusion We concluded that drugs may interfere in sensorimotor processes, such as in the performance of tasks carried out in an unpredictable scenario.
publishDate 2015
dc.date.none.fl_str_mv 2015-11-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001100918
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001100918
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0004-282X20150140
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.73 n.11 2015
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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