Critical analysis on the present methods for brain volume measurements in multiple sclerosis

Detalhes bibliográficos
Autor(a) principal: Fragoso,Yara Dadalti
Data de Publicação: 2017
Outros Autores: Willie,Paulo Roberto, Goncalves,Marcus Vinicius Magno, Brooks,Joseph Bruno Bidin
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000700464
Resumo: ABSTRACT Objective The treatment of multiple sclerosis (MS) has quickly evolved from a time when controlling clinical relapses would suffice, to the present day, when complete disease control is expected. Measurement of brain volume is still at an early stage to be indicative of therapeutic decisions in MS. Methods This paper provides a critical review of potential biases and artifacts in brain measurement in the follow-up of patients with MS. Results Clinical conditions (such as hydration or ovulation), time of the day, type of magnetic resonance machine (manufacturer and potency), brain volume artifacts and different platforms for volumetric assessment of the brain can induce variations that exceed the acceptable physiological rate of annual loss of brain volume. Conclusion Although potentially extremely valuable, brain volume measurement still has to be regarded with caution in MS.
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spelling Critical analysis on the present methods for brain volume measurements in multiple sclerosismultiple sclerosisbrainatrophygray matterABSTRACT Objective The treatment of multiple sclerosis (MS) has quickly evolved from a time when controlling clinical relapses would suffice, to the present day, when complete disease control is expected. Measurement of brain volume is still at an early stage to be indicative of therapeutic decisions in MS. Methods This paper provides a critical review of potential biases and artifacts in brain measurement in the follow-up of patients with MS. Results Clinical conditions (such as hydration or ovulation), time of the day, type of magnetic resonance machine (manufacturer and potency), brain volume artifacts and different platforms for volumetric assessment of the brain can induce variations that exceed the acceptable physiological rate of annual loss of brain volume. Conclusion Although potentially extremely valuable, brain volume measurement still has to be regarded with caution in MS.Academia Brasileira de Neurologia - ABNEURO2017-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000700464Arquivos de Neuro-Psiquiatria v.75 n.7 2017reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x20170072info:eu-repo/semantics/openAccessFragoso,Yara DadaltiWillie,Paulo RobertoGoncalves,Marcus Vinicius MagnoBrooks,Joseph Bruno Bidineng2018-04-02T00:00:00Zoai:scielo:S0004-282X2017000700464Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2018-04-02T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Critical analysis on the present methods for brain volume measurements in multiple sclerosis
title Critical analysis on the present methods for brain volume measurements in multiple sclerosis
spellingShingle Critical analysis on the present methods for brain volume measurements in multiple sclerosis
Fragoso,Yara Dadalti
multiple sclerosis
brain
atrophy
gray matter
title_short Critical analysis on the present methods for brain volume measurements in multiple sclerosis
title_full Critical analysis on the present methods for brain volume measurements in multiple sclerosis
title_fullStr Critical analysis on the present methods for brain volume measurements in multiple sclerosis
title_full_unstemmed Critical analysis on the present methods for brain volume measurements in multiple sclerosis
title_sort Critical analysis on the present methods for brain volume measurements in multiple sclerosis
author Fragoso,Yara Dadalti
author_facet Fragoso,Yara Dadalti
Willie,Paulo Roberto
Goncalves,Marcus Vinicius Magno
Brooks,Joseph Bruno Bidin
author_role author
author2 Willie,Paulo Roberto
Goncalves,Marcus Vinicius Magno
Brooks,Joseph Bruno Bidin
author2_role author
author
author
dc.contributor.author.fl_str_mv Fragoso,Yara Dadalti
Willie,Paulo Roberto
Goncalves,Marcus Vinicius Magno
Brooks,Joseph Bruno Bidin
dc.subject.por.fl_str_mv multiple sclerosis
brain
atrophy
gray matter
topic multiple sclerosis
brain
atrophy
gray matter
description ABSTRACT Objective The treatment of multiple sclerosis (MS) has quickly evolved from a time when controlling clinical relapses would suffice, to the present day, when complete disease control is expected. Measurement of brain volume is still at an early stage to be indicative of therapeutic decisions in MS. Methods This paper provides a critical review of potential biases and artifacts in brain measurement in the follow-up of patients with MS. Results Clinical conditions (such as hydration or ovulation), time of the day, type of magnetic resonance machine (manufacturer and potency), brain volume artifacts and different platforms for volumetric assessment of the brain can induce variations that exceed the acceptable physiological rate of annual loss of brain volume. Conclusion Although potentially extremely valuable, brain volume measurement still has to be regarded with caution in MS.
publishDate 2017
dc.date.none.fl_str_mv 2017-07-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000700464
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000700464
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0004-282x20170072
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.75 n.7 2017
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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