Transaxonal degenerations of cerebellar connections: the value of anatomical knowledge
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000500301 |
Resumo: | ABSTRACT Transaxonal degenerations result from neuronal death or the interruption of synaptic connections among neuronal structures. These degenerations are not common but may be recognized by conventional magnetic resonance imaging. Objective: The learning objectives of this review include recognition of the imaging characteristics of transaxonal degenerations involving cerebellar connections, the identification of potential encephalic lesions that can lead to these degenerations and correlation of the clinical manifestations with imaging findings that reflect this involvement. Methods: In this report, we review the neuroanatomical knowledge that provides a basis for identifying potential lesions that can result in these degenerations involving cerebellar structures. Results: Hypertrophic olivary degeneration results from an injury that interrupts any of the components of the Guillain-Mollaret triangle. In this work, we describe cases of lesions in the dentate nucleus and central tegmental tract. The crossed cerebellar diaschisis presents specific imaging findings and clinical correlations associated with its acute and chronic phases. The Wallerian degeneration of the middle cerebellar peduncle is illustrated by fiber injury of the pontine cerebellar tracts. A T2-hyperintensity in the dentate nucleus due to a thalamic acute lesion (in ventral lateral nuclei) is also described. Each condition described here is documented by MRI images and is accompanied by teaching points and an anatomical review of the pathways involved. Conclusion: Neurologists and radiologists need to become familiar with the diagnosis of these conditions since their presentations are peculiar and often subtle, and can easily be misdiagnosed as ischemic events, degenerative disease, demyelinating disease or even tumors. |
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Transaxonal degenerations of cerebellar connections: the value of anatomical knowledgeStatus EpilepticusMiddle Cerebellar PeduncleOlivary NucleusCerebellar NucleiRed NucleusABSTRACT Transaxonal degenerations result from neuronal death or the interruption of synaptic connections among neuronal structures. These degenerations are not common but may be recognized by conventional magnetic resonance imaging. Objective: The learning objectives of this review include recognition of the imaging characteristics of transaxonal degenerations involving cerebellar connections, the identification of potential encephalic lesions that can lead to these degenerations and correlation of the clinical manifestations with imaging findings that reflect this involvement. Methods: In this report, we review the neuroanatomical knowledge that provides a basis for identifying potential lesions that can result in these degenerations involving cerebellar structures. Results: Hypertrophic olivary degeneration results from an injury that interrupts any of the components of the Guillain-Mollaret triangle. In this work, we describe cases of lesions in the dentate nucleus and central tegmental tract. The crossed cerebellar diaschisis presents specific imaging findings and clinical correlations associated with its acute and chronic phases. The Wallerian degeneration of the middle cerebellar peduncle is illustrated by fiber injury of the pontine cerebellar tracts. A T2-hyperintensity in the dentate nucleus due to a thalamic acute lesion (in ventral lateral nuclei) is also described. Each condition described here is documented by MRI images and is accompanied by teaching points and an anatomical review of the pathways involved. Conclusion: Neurologists and radiologists need to become familiar with the diagnosis of these conditions since their presentations are peculiar and often subtle, and can easily be misdiagnosed as ischemic events, degenerative disease, demyelinating disease or even tumors.Academia Brasileira de Neurologia - ABNEURO2020-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000500301Arquivos de Neuro-Psiquiatria v.78 n.5 2020reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x20200021info:eu-repo/semantics/openAccessRAEDER,Mariana Trombetta de LimaREIS,Eduardo PontesCAMPOS,Brunno MachadoZAMILUTE,Igor Aloísio GarcezFRANÇA JÚNIOR,Marcondes CavalcanteREIS,Fabianoeng2020-05-27T00:00:00Zoai:scielo:S0004-282X2020000500301Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2020-05-27T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Transaxonal degenerations of cerebellar connections: the value of anatomical knowledge |
title |
Transaxonal degenerations of cerebellar connections: the value of anatomical knowledge |
spellingShingle |
Transaxonal degenerations of cerebellar connections: the value of anatomical knowledge RAEDER,Mariana Trombetta de Lima Status Epilepticus Middle Cerebellar Peduncle Olivary Nucleus Cerebellar Nuclei Red Nucleus |
title_short |
Transaxonal degenerations of cerebellar connections: the value of anatomical knowledge |
title_full |
Transaxonal degenerations of cerebellar connections: the value of anatomical knowledge |
title_fullStr |
Transaxonal degenerations of cerebellar connections: the value of anatomical knowledge |
title_full_unstemmed |
Transaxonal degenerations of cerebellar connections: the value of anatomical knowledge |
title_sort |
Transaxonal degenerations of cerebellar connections: the value of anatomical knowledge |
author |
RAEDER,Mariana Trombetta de Lima |
author_facet |
RAEDER,Mariana Trombetta de Lima REIS,Eduardo Pontes CAMPOS,Brunno Machado ZAMILUTE,Igor Aloísio Garcez FRANÇA JÚNIOR,Marcondes Cavalcante REIS,Fabiano |
author_role |
author |
author2 |
REIS,Eduardo Pontes CAMPOS,Brunno Machado ZAMILUTE,Igor Aloísio Garcez FRANÇA JÚNIOR,Marcondes Cavalcante REIS,Fabiano |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
RAEDER,Mariana Trombetta de Lima REIS,Eduardo Pontes CAMPOS,Brunno Machado ZAMILUTE,Igor Aloísio Garcez FRANÇA JÚNIOR,Marcondes Cavalcante REIS,Fabiano |
dc.subject.por.fl_str_mv |
Status Epilepticus Middle Cerebellar Peduncle Olivary Nucleus Cerebellar Nuclei Red Nucleus |
topic |
Status Epilepticus Middle Cerebellar Peduncle Olivary Nucleus Cerebellar Nuclei Red Nucleus |
description |
ABSTRACT Transaxonal degenerations result from neuronal death or the interruption of synaptic connections among neuronal structures. These degenerations are not common but may be recognized by conventional magnetic resonance imaging. Objective: The learning objectives of this review include recognition of the imaging characteristics of transaxonal degenerations involving cerebellar connections, the identification of potential encephalic lesions that can lead to these degenerations and correlation of the clinical manifestations with imaging findings that reflect this involvement. Methods: In this report, we review the neuroanatomical knowledge that provides a basis for identifying potential lesions that can result in these degenerations involving cerebellar structures. Results: Hypertrophic olivary degeneration results from an injury that interrupts any of the components of the Guillain-Mollaret triangle. In this work, we describe cases of lesions in the dentate nucleus and central tegmental tract. The crossed cerebellar diaschisis presents specific imaging findings and clinical correlations associated with its acute and chronic phases. The Wallerian degeneration of the middle cerebellar peduncle is illustrated by fiber injury of the pontine cerebellar tracts. A T2-hyperintensity in the dentate nucleus due to a thalamic acute lesion (in ventral lateral nuclei) is also described. Each condition described here is documented by MRI images and is accompanied by teaching points and an anatomical review of the pathways involved. Conclusion: Neurologists and radiologists need to become familiar with the diagnosis of these conditions since their presentations are peculiar and often subtle, and can easily be misdiagnosed as ischemic events, degenerative disease, demyelinating disease or even tumors. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-05-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000500301 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000500301 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282x20200021 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.78 n.5 2020 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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1754212786433425408 |