Mary Broadfoot Walker: 83 years since a historical discovery

Detalhes bibliográficos
Autor(a) principal: Carvalho,Vitor Martinez de
Data de Publicação: 2017
Outros Autores: Nogueira,Eduardo de Almeida Guimarães, Rosa,Gleysson Rodrigues, Fragoso,Yara Dadalti
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017001100825
Resumo: ABSTRACT Mary Broadfoot Walker was a Scottish physician who, in 1935, described in great detail the effect of an anticholinesterase drug (physostigmine) on the signs and symptoms of myasthenia gravis. An original five-minutes movie is available online and the skepticism of her contemporary British medical doctors is understandable when the drastic effect of the treatment is shown in this movie. What Mary Walker taught us, more than eight decades ago, about myasthenia gravis continues to be the basis of a pharmacological diagnostic test and treatment of this disease.
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spelling Mary Broadfoot Walker: 83 years since a historical discoverymyasthenia gravisphysostigmineneostigmineacetylcholinesteraseABSTRACT Mary Broadfoot Walker was a Scottish physician who, in 1935, described in great detail the effect of an anticholinesterase drug (physostigmine) on the signs and symptoms of myasthenia gravis. An original five-minutes movie is available online and the skepticism of her contemporary British medical doctors is understandable when the drastic effect of the treatment is shown in this movie. What Mary Walker taught us, more than eight decades ago, about myasthenia gravis continues to be the basis of a pharmacological diagnostic test and treatment of this disease.Academia Brasileira de Neurologia - ABNEURO2017-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017001100825Arquivos de Neuro-Psiquiatria v.75 n.11 2017reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x20170138info:eu-repo/semantics/openAccessCarvalho,Vitor Martinez deNogueira,Eduardo de Almeida GuimarãesRosa,Gleysson RodriguesFragoso,Yara Dadaltieng2017-12-05T00:00:00Zoai:scielo:S0004-282X2017001100825Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2017-12-05T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Mary Broadfoot Walker: 83 years since a historical discovery
title Mary Broadfoot Walker: 83 years since a historical discovery
spellingShingle Mary Broadfoot Walker: 83 years since a historical discovery
Carvalho,Vitor Martinez de
myasthenia gravis
physostigmine
neostigmine
acetylcholinesterase
title_short Mary Broadfoot Walker: 83 years since a historical discovery
title_full Mary Broadfoot Walker: 83 years since a historical discovery
title_fullStr Mary Broadfoot Walker: 83 years since a historical discovery
title_full_unstemmed Mary Broadfoot Walker: 83 years since a historical discovery
title_sort Mary Broadfoot Walker: 83 years since a historical discovery
author Carvalho,Vitor Martinez de
author_facet Carvalho,Vitor Martinez de
Nogueira,Eduardo de Almeida Guimarães
Rosa,Gleysson Rodrigues
Fragoso,Yara Dadalti
author_role author
author2 Nogueira,Eduardo de Almeida Guimarães
Rosa,Gleysson Rodrigues
Fragoso,Yara Dadalti
author2_role author
author
author
dc.contributor.author.fl_str_mv Carvalho,Vitor Martinez de
Nogueira,Eduardo de Almeida Guimarães
Rosa,Gleysson Rodrigues
Fragoso,Yara Dadalti
dc.subject.por.fl_str_mv myasthenia gravis
physostigmine
neostigmine
acetylcholinesterase
topic myasthenia gravis
physostigmine
neostigmine
acetylcholinesterase
description ABSTRACT Mary Broadfoot Walker was a Scottish physician who, in 1935, described in great detail the effect of an anticholinesterase drug (physostigmine) on the signs and symptoms of myasthenia gravis. An original five-minutes movie is available online and the skepticism of her contemporary British medical doctors is understandable when the drastic effect of the treatment is shown in this movie. What Mary Walker taught us, more than eight decades ago, about myasthenia gravis continues to be the basis of a pharmacological diagnostic test and treatment of this disease.
publishDate 2017
dc.date.none.fl_str_mv 2017-11-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017001100825
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017001100825
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0004-282x20170138
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.75 n.11 2017
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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