Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000500277 |
Resumo: | ABSTRACT Background: Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder caused by progressive deposition of β-amyloid peptides in the walls of small and medium-sized cortical and leptomeningeal vessels. Until today, the prevalence of CAA is unknown in our region. Objective: This study aims to analyze the prevalence of this entity in a specific elderly population in a tertiary hospital in Northeastern Brazil. Methods: A cross-sectional, retrospective study with the enrollment of patients aged 65 or older followed in the neurological outpatient service of the Universidade Federal do Piauí, Brazil, who underwent brain magnetic resonance imaging (MRI) from July 2016 to June 2018. Results: One hundred and seventy-four patients were enrolled, of whom 100 were women (57.4%) and 74, men (42.6%), aged from 65 to 91 years old (median age 73.27). Nine patients were excluded from the study due to unavailability of MRI sequences needed for an appropriate analysis. Out of the 165 remaining patients, 12 (7.2%) had established the diagnosis of CAA, according to the modified Boston criteria. Conclusion: The prevalence of CAA in our study was like those of medical literature, with a progressive age-related increase. |
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Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern BrazilCerebral Amyloid AngiopathyCerebral HemorrhageABSTRACT Background: Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder caused by progressive deposition of β-amyloid peptides in the walls of small and medium-sized cortical and leptomeningeal vessels. Until today, the prevalence of CAA is unknown in our region. Objective: This study aims to analyze the prevalence of this entity in a specific elderly population in a tertiary hospital in Northeastern Brazil. Methods: A cross-sectional, retrospective study with the enrollment of patients aged 65 or older followed in the neurological outpatient service of the Universidade Federal do Piauí, Brazil, who underwent brain magnetic resonance imaging (MRI) from July 2016 to June 2018. Results: One hundred and seventy-four patients were enrolled, of whom 100 were women (57.4%) and 74, men (42.6%), aged from 65 to 91 years old (median age 73.27). Nine patients were excluded from the study due to unavailability of MRI sequences needed for an appropriate analysis. Out of the 165 remaining patients, 12 (7.2%) had established the diagnosis of CAA, according to the modified Boston criteria. Conclusion: The prevalence of CAA in our study was like those of medical literature, with a progressive age-related increase.Academia Brasileira de Neurologia - ABNEURO2020-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000500277Arquivos de Neuro-Psiquiatria v.78 n.5 2020reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x20200007info:eu-repo/semantics/openAccessBARROS-ARAÚJO,Marx Lima deRICARTE,Irapuá FerreiraMONTALVERNE FILHO,EdwardHOLANDA,Guilherme Marconi Guimarães MartinsSOUSA,Ícaro Araújo deCORRÊA,Matheus RodriguesNOGUEIRA,Matheus Rocha de SeixasCRONEMBERGER,Pedro Jorge Luz Alveseng2020-05-27T00:00:00Zoai:scielo:S0004-282X2020000500277Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2020-05-27T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil |
title |
Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil |
spellingShingle |
Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil BARROS-ARAÚJO,Marx Lima de Cerebral Amyloid Angiopathy Cerebral Hemorrhage |
title_short |
Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil |
title_full |
Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil |
title_fullStr |
Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil |
title_full_unstemmed |
Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil |
title_sort |
Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil |
author |
BARROS-ARAÚJO,Marx Lima de |
author_facet |
BARROS-ARAÚJO,Marx Lima de RICARTE,Irapuá Ferreira MONTALVERNE FILHO,Edward HOLANDA,Guilherme Marconi Guimarães Martins SOUSA,Ícaro Araújo de CORRÊA,Matheus Rodrigues NOGUEIRA,Matheus Rocha de Seixas CRONEMBERGER,Pedro Jorge Luz Alves |
author_role |
author |
author2 |
RICARTE,Irapuá Ferreira MONTALVERNE FILHO,Edward HOLANDA,Guilherme Marconi Guimarães Martins SOUSA,Ícaro Araújo de CORRÊA,Matheus Rodrigues NOGUEIRA,Matheus Rocha de Seixas CRONEMBERGER,Pedro Jorge Luz Alves |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
BARROS-ARAÚJO,Marx Lima de RICARTE,Irapuá Ferreira MONTALVERNE FILHO,Edward HOLANDA,Guilherme Marconi Guimarães Martins SOUSA,Ícaro Araújo de CORRÊA,Matheus Rodrigues NOGUEIRA,Matheus Rocha de Seixas CRONEMBERGER,Pedro Jorge Luz Alves |
dc.subject.por.fl_str_mv |
Cerebral Amyloid Angiopathy Cerebral Hemorrhage |
topic |
Cerebral Amyloid Angiopathy Cerebral Hemorrhage |
description |
ABSTRACT Background: Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder caused by progressive deposition of β-amyloid peptides in the walls of small and medium-sized cortical and leptomeningeal vessels. Until today, the prevalence of CAA is unknown in our region. Objective: This study aims to analyze the prevalence of this entity in a specific elderly population in a tertiary hospital in Northeastern Brazil. Methods: A cross-sectional, retrospective study with the enrollment of patients aged 65 or older followed in the neurological outpatient service of the Universidade Federal do Piauí, Brazil, who underwent brain magnetic resonance imaging (MRI) from July 2016 to June 2018. Results: One hundred and seventy-four patients were enrolled, of whom 100 were women (57.4%) and 74, men (42.6%), aged from 65 to 91 years old (median age 73.27). Nine patients were excluded from the study due to unavailability of MRI sequences needed for an appropriate analysis. Out of the 165 remaining patients, 12 (7.2%) had established the diagnosis of CAA, according to the modified Boston criteria. Conclusion: The prevalence of CAA in our study was like those of medical literature, with a progressive age-related increase. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-05-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000500277 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000500277 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282x20200007 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.78 n.5 2020 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
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