Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil

Detalhes bibliográficos
Autor(a) principal: BARROS-ARAÚJO,Marx Lima de
Data de Publicação: 2020
Outros Autores: RICARTE,Irapuá Ferreira, MONTALVERNE FILHO,Edward, HOLANDA,Guilherme Marconi Guimarães Martins, SOUSA,Ícaro Araújo de, CORRÊA,Matheus Rodrigues, NOGUEIRA,Matheus Rocha de Seixas, CRONEMBERGER,Pedro Jorge Luz Alves
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000500277
Resumo: ABSTRACT Background: Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder caused by progressive deposition of β-amyloid peptides in the walls of small and medium-sized cortical and leptomeningeal vessels. Until today, the prevalence of CAA is unknown in our region. Objective: This study aims to analyze the prevalence of this entity in a specific elderly population in a tertiary hospital in Northeastern Brazil. Methods: A cross-sectional, retrospective study with the enrollment of patients aged 65 or older followed in the neurological outpatient service of the Universidade Federal do Piauí, Brazil, who underwent brain magnetic resonance imaging (MRI) from July 2016 to June 2018. Results: One hundred and seventy-four patients were enrolled, of whom 100 were women (57.4%) and 74, men (42.6%), aged from 65 to 91 years old (median age 73.27). Nine patients were excluded from the study due to unavailability of MRI sequences needed for an appropriate analysis. Out of the 165 remaining patients, 12 (7.2%) had established the diagnosis of CAA, according to the modified Boston criteria. Conclusion: The prevalence of CAA in our study was like those of medical literature, with a progressive age-related increase.
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spelling Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern BrazilCerebral Amyloid AngiopathyCerebral HemorrhageABSTRACT Background: Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder caused by progressive deposition of β-amyloid peptides in the walls of small and medium-sized cortical and leptomeningeal vessels. Until today, the prevalence of CAA is unknown in our region. Objective: This study aims to analyze the prevalence of this entity in a specific elderly population in a tertiary hospital in Northeastern Brazil. Methods: A cross-sectional, retrospective study with the enrollment of patients aged 65 or older followed in the neurological outpatient service of the Universidade Federal do Piauí, Brazil, who underwent brain magnetic resonance imaging (MRI) from July 2016 to June 2018. Results: One hundred and seventy-four patients were enrolled, of whom 100 were women (57.4%) and 74, men (42.6%), aged from 65 to 91 years old (median age 73.27). Nine patients were excluded from the study due to unavailability of MRI sequences needed for an appropriate analysis. Out of the 165 remaining patients, 12 (7.2%) had established the diagnosis of CAA, according to the modified Boston criteria. Conclusion: The prevalence of CAA in our study was like those of medical literature, with a progressive age-related increase.Academia Brasileira de Neurologia - ABNEURO2020-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000500277Arquivos de Neuro-Psiquiatria v.78 n.5 2020reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x20200007info:eu-repo/semantics/openAccessBARROS-ARAÚJO,Marx Lima deRICARTE,Irapuá FerreiraMONTALVERNE FILHO,EdwardHOLANDA,Guilherme Marconi Guimarães MartinsSOUSA,Ícaro Araújo deCORRÊA,Matheus RodriguesNOGUEIRA,Matheus Rocha de SeixasCRONEMBERGER,Pedro Jorge Luz Alveseng2020-05-27T00:00:00Zoai:scielo:S0004-282X2020000500277Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2020-05-27T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil
title Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil
spellingShingle Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil
BARROS-ARAÚJO,Marx Lima de
Cerebral Amyloid Angiopathy
Cerebral Hemorrhage
title_short Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil
title_full Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil
title_fullStr Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil
title_full_unstemmed Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil
title_sort Cerebral amyloid angiopathy: a cross-sectional study in a single center in Northeastern Brazil
author BARROS-ARAÚJO,Marx Lima de
author_facet BARROS-ARAÚJO,Marx Lima de
RICARTE,Irapuá Ferreira
MONTALVERNE FILHO,Edward
HOLANDA,Guilherme Marconi Guimarães Martins
SOUSA,Ícaro Araújo de
CORRÊA,Matheus Rodrigues
NOGUEIRA,Matheus Rocha de Seixas
CRONEMBERGER,Pedro Jorge Luz Alves
author_role author
author2 RICARTE,Irapuá Ferreira
MONTALVERNE FILHO,Edward
HOLANDA,Guilherme Marconi Guimarães Martins
SOUSA,Ícaro Araújo de
CORRÊA,Matheus Rodrigues
NOGUEIRA,Matheus Rocha de Seixas
CRONEMBERGER,Pedro Jorge Luz Alves
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv BARROS-ARAÚJO,Marx Lima de
RICARTE,Irapuá Ferreira
MONTALVERNE FILHO,Edward
HOLANDA,Guilherme Marconi Guimarães Martins
SOUSA,Ícaro Araújo de
CORRÊA,Matheus Rodrigues
NOGUEIRA,Matheus Rocha de Seixas
CRONEMBERGER,Pedro Jorge Luz Alves
dc.subject.por.fl_str_mv Cerebral Amyloid Angiopathy
Cerebral Hemorrhage
topic Cerebral Amyloid Angiopathy
Cerebral Hemorrhage
description ABSTRACT Background: Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder caused by progressive deposition of β-amyloid peptides in the walls of small and medium-sized cortical and leptomeningeal vessels. Until today, the prevalence of CAA is unknown in our region. Objective: This study aims to analyze the prevalence of this entity in a specific elderly population in a tertiary hospital in Northeastern Brazil. Methods: A cross-sectional, retrospective study with the enrollment of patients aged 65 or older followed in the neurological outpatient service of the Universidade Federal do Piauí, Brazil, who underwent brain magnetic resonance imaging (MRI) from July 2016 to June 2018. Results: One hundred and seventy-four patients were enrolled, of whom 100 were women (57.4%) and 74, men (42.6%), aged from 65 to 91 years old (median age 73.27). Nine patients were excluded from the study due to unavailability of MRI sequences needed for an appropriate analysis. Out of the 165 remaining patients, 12 (7.2%) had established the diagnosis of CAA, according to the modified Boston criteria. Conclusion: The prevalence of CAA in our study was like those of medical literature, with a progressive age-related increase.
publishDate 2020
dc.date.none.fl_str_mv 2020-05-01
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000500277
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dc.language.iso.fl_str_mv eng
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dc.relation.none.fl_str_mv 10.1590/0004-282x20200007
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dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.78 n.5 2020
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
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instname_str Academia Brasileira de Neurologia
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reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
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