Predictors of hemorrhagic transformation after acute ischemic stroke based on the experts’ opinion
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000700390 |
Resumo: | ABSTRACT Background: Hemorrhagic transformation (HT) is a common complication after ischemic stroke. It may be associated to poor outcomes. Some predictors of HT have been previously identified, but there remain controversies. Objective: To describe the risk factors for HT more frequently reported by a panel of experts surveyed for this project. Methods: We sent a standard questionnaire by e-mail to specialists in Vascular Neurology from 2014 to 2018. Forty-five specialists were contacted and 20 of them responded to the invitation. Predictors cited by three or more specialists were included in a table and ranked by the frequency in which they appeared. A review of the literature looking for published predictive scores of HT was performed, comparing to the answers received. Results: The 20 responding specialists cited 23 different risk factors for HT. The most frequent factors in the order of citation were the volume of ischemia, previous use of antithrombotic medication, neurological severity, age, hyperglycemia at presentation, hypertension on admission, and cardioembolism. Most variables were also found in previously published predictive scores, but they were reported by the authors with divergences of frequency. Conclusion: Although many studies have evaluated HT in patients with acute ischemic stroke, the published risk factors were neither uniform nor in agreement with those cited by the stroke specialists. These findings may be helpful to build a score that can be tested with the goal of improving the prediction of HT. |
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Predictors of hemorrhagic transformation after acute ischemic stroke based on the experts’ opinionacute ischemic strokehemorrhagic transformationneurological complicationABSTRACT Background: Hemorrhagic transformation (HT) is a common complication after ischemic stroke. It may be associated to poor outcomes. Some predictors of HT have been previously identified, but there remain controversies. Objective: To describe the risk factors for HT more frequently reported by a panel of experts surveyed for this project. Methods: We sent a standard questionnaire by e-mail to specialists in Vascular Neurology from 2014 to 2018. Forty-five specialists were contacted and 20 of them responded to the invitation. Predictors cited by three or more specialists were included in a table and ranked by the frequency in which they appeared. A review of the literature looking for published predictive scores of HT was performed, comparing to the answers received. Results: The 20 responding specialists cited 23 different risk factors for HT. The most frequent factors in the order of citation were the volume of ischemia, previous use of antithrombotic medication, neurological severity, age, hyperglycemia at presentation, hypertension on admission, and cardioembolism. Most variables were also found in previously published predictive scores, but they were reported by the authors with divergences of frequency. Conclusion: Although many studies have evaluated HT in patients with acute ischemic stroke, the published risk factors were neither uniform nor in agreement with those cited by the stroke specialists. These findings may be helpful to build a score that can be tested with the goal of improving the prediction of HT.Academia Brasileira de Neurologia - ABNEURO2020-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000700390Arquivos de Neuro-Psiquiatria v.78 n.7 2020reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x20200008info:eu-repo/semantics/openAccessANDRADE,João Brainer Clares deMOHR,Jay PrestonLIMA,Fabricio OliveiraBARROS,Levi Coelho MaiaNEPOMUCENO,Camila RodriguesPORTELA,Leonardo BarreiraSILVA,Gisele Sampaioeng2020-07-29T00:00:00Zoai:scielo:S0004-282X2020000700390Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2020-07-29T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Predictors of hemorrhagic transformation after acute ischemic stroke based on the experts’ opinion |
title |
Predictors of hemorrhagic transformation after acute ischemic stroke based on the experts’ opinion |
spellingShingle |
Predictors of hemorrhagic transformation after acute ischemic stroke based on the experts’ opinion ANDRADE,João Brainer Clares de acute ischemic stroke hemorrhagic transformation neurological complication |
title_short |
Predictors of hemorrhagic transformation after acute ischemic stroke based on the experts’ opinion |
title_full |
Predictors of hemorrhagic transformation after acute ischemic stroke based on the experts’ opinion |
title_fullStr |
Predictors of hemorrhagic transformation after acute ischemic stroke based on the experts’ opinion |
title_full_unstemmed |
Predictors of hemorrhagic transformation after acute ischemic stroke based on the experts’ opinion |
title_sort |
Predictors of hemorrhagic transformation after acute ischemic stroke based on the experts’ opinion |
author |
ANDRADE,João Brainer Clares de |
author_facet |
ANDRADE,João Brainer Clares de MOHR,Jay Preston LIMA,Fabricio Oliveira BARROS,Levi Coelho Maia NEPOMUCENO,Camila Rodrigues PORTELA,Leonardo Barreira SILVA,Gisele Sampaio |
author_role |
author |
author2 |
MOHR,Jay Preston LIMA,Fabricio Oliveira BARROS,Levi Coelho Maia NEPOMUCENO,Camila Rodrigues PORTELA,Leonardo Barreira SILVA,Gisele Sampaio |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
ANDRADE,João Brainer Clares de MOHR,Jay Preston LIMA,Fabricio Oliveira BARROS,Levi Coelho Maia NEPOMUCENO,Camila Rodrigues PORTELA,Leonardo Barreira SILVA,Gisele Sampaio |
dc.subject.por.fl_str_mv |
acute ischemic stroke hemorrhagic transformation neurological complication |
topic |
acute ischemic stroke hemorrhagic transformation neurological complication |
description |
ABSTRACT Background: Hemorrhagic transformation (HT) is a common complication after ischemic stroke. It may be associated to poor outcomes. Some predictors of HT have been previously identified, but there remain controversies. Objective: To describe the risk factors for HT more frequently reported by a panel of experts surveyed for this project. Methods: We sent a standard questionnaire by e-mail to specialists in Vascular Neurology from 2014 to 2018. Forty-five specialists were contacted and 20 of them responded to the invitation. Predictors cited by three or more specialists were included in a table and ranked by the frequency in which they appeared. A review of the literature looking for published predictive scores of HT was performed, comparing to the answers received. Results: The 20 responding specialists cited 23 different risk factors for HT. The most frequent factors in the order of citation were the volume of ischemia, previous use of antithrombotic medication, neurological severity, age, hyperglycemia at presentation, hypertension on admission, and cardioembolism. Most variables were also found in previously published predictive scores, but they were reported by the authors with divergences of frequency. Conclusion: Although many studies have evaluated HT in patients with acute ischemic stroke, the published risk factors were neither uniform nor in agreement with those cited by the stroke specialists. These findings may be helpful to build a score that can be tested with the goal of improving the prediction of HT. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-07-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000700390 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000700390 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282x20200008 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.78 n.7 2020 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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1754212787346735104 |