IMPACT OF ARTERIAL HYPERTENSION ON HEMORRHAGIC STROKE

• Autor(a) principal: Cunha, Inês
• Data de Publicação: 2023
• Outros Autores: Cunha, Joana, Matos, César, Machado, Sara, Pinto, Ana, Agudo, Margarida, Assunção, António, Andrade, Joana, Marques, Rui, Romão, Vera, Gomes, Ana
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://doi.org/10.58043/rphrc.59
• topic: Hipertensão arterial; AVC hemorrágico; AVC isquémico; Arterial hypertension; hemorrhagic stroke; ischemic stroke

Introduction: Cerebrovascular diseases continue to be one of the leading causes of morbidity and mortality worldwide. Although less frequent than ischemic strokes, hemorrhagic strokes have higher mortality rates and have arterial hypertension (AHT) as the main risk factor. Objectives: Analyze the prevalence of AHT in patients hospitalized for hemorrhagic stroke, the demographic characteristics of this population and the impact of AHT on 30-day mortality. Methods: Retrospective analysis of patients hospitalized for hemorrhagic stroke in the Centro Hospitalar Tondela-Viseu Stroke Unit, over a year, using SClínico records and analyzing the data using SPSS®. Results: The sample consisted of 89 patients, with a mean age of 72.81 ± 12.81 years, 39.3% female. 60.7% had a history of AHT, of which 81.5% were medicated with antihypertensive therapy. The mean age was similar in the group with and without AHT (72.87 vs 72.71 years, p=0.950). In the hypertension group, 42.6% were women and 34.3% were women in the non-hypertensive group (p=0.433). On average, when admitted to the emergency department, the systolic blood pressure (SBP) was 170 mmHg and the diastolic blood pressure (DBP) was 91 mmHg; 79.8% of the patients had at admission SBP greater than or equal to 140 mmHg and 51.7% had DBP greater than or equal to 90 mmHg. When compared to patients hospitalized this year with ischemic stroke (n=322), the mean value of SBP and DBP at admission was significantly higher in the group with hemorrhagic stroke (respectively, 154 vs 170 mmHg, p=0.000 and 85 vs 91 mmHg, p=0.003), although the prevalence of previously diagnosed AHT was not significantly higher (55.6% of patients with ischemic stroke also have AHT, p=0.392). In patients with hemorrhagic stroke there was no statistically significant difference between the groups with and without history of AHT regarding 30-day mortality (16.7% vs 20.0%, p=0.689). The SBP at admission was only slightly higher in the group of patients who died in the first month compared to survivors (171 vs 169 mmHg, p=0.819), whereas the DBP was on average lower, but also without reaching statistical significance (85 vs 92 mmHg, p=0.163). Conclusion: AHT proved to be highly prevalent in hospitalized patients with hemorrhagic stroke, with more than half of patients diagnosed with AHT prior to the event. Although most of these were on antihypertensive drugs, most had uncontrolled blood pressure values higher than hospitalized patients with ischemic stroke. The previous diagnosis of AHT had no statistically significant impact on mortality in patients with hemorrhagic stroke, at least in a short period of time, but more studies are needed, namely regarding the impact on long-term mortality and the repetition of cerebrovascular events.