Hemangioblastoma of the posterior fossa: the role of multimodality treatment
Autor(a) principal: | |
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Data de Publicação: | 1997 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1997000200016 |
Resumo: | The authors made a review of a series of patients with hemangioblastomas of the posterior fossa treated between 1973 and 1993. A total of 32 patients were analyzed with 24 patients receiving resection, 8 patients receiving radiosurgery and 2 patients receiving conventional radiotherapy. The mortality in the patients with a resection was considered acceptable with 2 deaths (8%) and with a morbidity of 3 patients (12.5%). A review of the literature suggests that conventional radiotherapy with high doses (45-60 Gy) may have a role in the post-operative control of hemangioblastomas and in some cases could be employed even before the resection in order to facilitate the surgery. The radiosurgical treatment is regarded like adjuvant. Poor results were obtained with radiosurgery in large tumors where low doses (less than 20 Gy) were used. Because of the rarity and complexity of these tumors, mainly when associated with von Hippel-Lindau disease, a multicenter study could be useful with the assessment of the optimal utilization and combination of these treatment modalities. |
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Hemangioblastoma of the posterior fossa: the role of multimodality treatmenthemangioblastomatreatmentradiosurgeryradiotherapyThe authors made a review of a series of patients with hemangioblastomas of the posterior fossa treated between 1973 and 1993. A total of 32 patients were analyzed with 24 patients receiving resection, 8 patients receiving radiosurgery and 2 patients receiving conventional radiotherapy. The mortality in the patients with a resection was considered acceptable with 2 deaths (8%) and with a morbidity of 3 patients (12.5%). A review of the literature suggests that conventional radiotherapy with high doses (45-60 Gy) may have a role in the post-operative control of hemangioblastomas and in some cases could be employed even before the resection in order to facilitate the surgery. The radiosurgical treatment is regarded like adjuvant. Poor results were obtained with radiosurgery in large tumors where low doses (less than 20 Gy) were used. Because of the rarity and complexity of these tumors, mainly when associated with von Hippel-Lindau disease, a multicenter study could be useful with the assessment of the optimal utilization and combination of these treatment modalities.Academia Brasileira de Neurologia - ABNEURO1997-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1997000200016Arquivos de Neuro-Psiquiatria v.55 n.2 1997reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X1997000200016info:eu-repo/semantics/openAccessGeorg,Alvaro E.Lunsford,L. DadeKondziolka,DouglasFlickinger,John C.Maitz,Anneng2010-11-10T00:00:00Zoai:scielo:S0004-282X1997000200016Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2010-11-10T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Hemangioblastoma of the posterior fossa: the role of multimodality treatment |
title |
Hemangioblastoma of the posterior fossa: the role of multimodality treatment |
spellingShingle |
Hemangioblastoma of the posterior fossa: the role of multimodality treatment Georg,Alvaro E. hemangioblastoma treatment radiosurgery radiotherapy |
title_short |
Hemangioblastoma of the posterior fossa: the role of multimodality treatment |
title_full |
Hemangioblastoma of the posterior fossa: the role of multimodality treatment |
title_fullStr |
Hemangioblastoma of the posterior fossa: the role of multimodality treatment |
title_full_unstemmed |
Hemangioblastoma of the posterior fossa: the role of multimodality treatment |
title_sort |
Hemangioblastoma of the posterior fossa: the role of multimodality treatment |
author |
Georg,Alvaro E. |
author_facet |
Georg,Alvaro E. Lunsford,L. Dade Kondziolka,Douglas Flickinger,John C. Maitz,Ann |
author_role |
author |
author2 |
Lunsford,L. Dade Kondziolka,Douglas Flickinger,John C. Maitz,Ann |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Georg,Alvaro E. Lunsford,L. Dade Kondziolka,Douglas Flickinger,John C. Maitz,Ann |
dc.subject.por.fl_str_mv |
hemangioblastoma treatment radiosurgery radiotherapy |
topic |
hemangioblastoma treatment radiosurgery radiotherapy |
description |
The authors made a review of a series of patients with hemangioblastomas of the posterior fossa treated between 1973 and 1993. A total of 32 patients were analyzed with 24 patients receiving resection, 8 patients receiving radiosurgery and 2 patients receiving conventional radiotherapy. The mortality in the patients with a resection was considered acceptable with 2 deaths (8%) and with a morbidity of 3 patients (12.5%). A review of the literature suggests that conventional radiotherapy with high doses (45-60 Gy) may have a role in the post-operative control of hemangioblastomas and in some cases could be employed even before the resection in order to facilitate the surgery. The radiosurgical treatment is regarded like adjuvant. Poor results were obtained with radiosurgery in large tumors where low doses (less than 20 Gy) were used. Because of the rarity and complexity of these tumors, mainly when associated with von Hippel-Lindau disease, a multicenter study could be useful with the assessment of the optimal utilization and combination of these treatment modalities. |
publishDate |
1997 |
dc.date.none.fl_str_mv |
1997-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1997000200016 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1997000200016 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-282X1997000200016 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.55 n.2 1997 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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1754212750367653888 |