Can the CERAD neuropsychological battery be used to assess cognitive impairment in Parkinson's disease?
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000300145 |
Resumo: | ABSTRACT The Consortium to Establish a Registry for Alzheimer's Disease (CERAD) neuropsychological battery was created to assess cognitive impairment in Alzheimer's disease (AD) but it is widely-used for various dementias. The aim of this study was to analyze the efficacy of using the CERAD battery in the assessment of patients with Parkinson's disease. Forty-nine patients with Parkinson's disease were divided into two groups (one with dementia and one without) using the Movement Disorder Society criteria for Parkinson's disease dementia. Cognitive deficits were assessed with the Clinical Dementia Rating Scale as the gold standard, and the CERAD. The ROC curve for the CERAD battery had an area under the curve = 0.989 (95% CI = 0.967 – 1, p<0.0001). Among the CERAD subtests, verbal fluency had the worst accuracy, and word list learning had the best accuracy. Despite the limits of this study, the CERAD battery can be efficient for assessment of cognitive deficits in Parkinson's disease patients. |
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Arquivos de neuro-psiquiatria (Online) |
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Can the CERAD neuropsychological battery be used to assess cognitive impairment in Parkinson's disease?Parkinson's diseasedementiacognitionABSTRACT The Consortium to Establish a Registry for Alzheimer's Disease (CERAD) neuropsychological battery was created to assess cognitive impairment in Alzheimer's disease (AD) but it is widely-used for various dementias. The aim of this study was to analyze the efficacy of using the CERAD battery in the assessment of patients with Parkinson's disease. Forty-nine patients with Parkinson's disease were divided into two groups (one with dementia and one without) using the Movement Disorder Society criteria for Parkinson's disease dementia. Cognitive deficits were assessed with the Clinical Dementia Rating Scale as the gold standard, and the CERAD. The ROC curve for the CERAD battery had an area under the curve = 0.989 (95% CI = 0.967 – 1, p<0.0001). Among the CERAD subtests, verbal fluency had the worst accuracy, and word list learning had the best accuracy. Despite the limits of this study, the CERAD battery can be efficient for assessment of cognitive deficits in Parkinson's disease patients.Academia Brasileira de Neurologia - ABNEURO2018-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000300145Arquivos de Neuro-Psiquiatria v.76 n.3 2018reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x20180003info:eu-repo/semantics/openAccessCamargo,Carlos Henrique FerreiraBronzini,AugustoTolentino,Eduardo de SouzaMedyk,CamilaSchultz-Pereira,Gustavo Leopoldeng2018-06-26T00:00:00Zoai:scielo:S0004-282X2018000300145Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2018-06-26T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Can the CERAD neuropsychological battery be used to assess cognitive impairment in Parkinson's disease? |
title |
Can the CERAD neuropsychological battery be used to assess cognitive impairment in Parkinson's disease? |
spellingShingle |
Can the CERAD neuropsychological battery be used to assess cognitive impairment in Parkinson's disease? Camargo,Carlos Henrique Ferreira Parkinson's disease dementia cognition |
title_short |
Can the CERAD neuropsychological battery be used to assess cognitive impairment in Parkinson's disease? |
title_full |
Can the CERAD neuropsychological battery be used to assess cognitive impairment in Parkinson's disease? |
title_fullStr |
Can the CERAD neuropsychological battery be used to assess cognitive impairment in Parkinson's disease? |
title_full_unstemmed |
Can the CERAD neuropsychological battery be used to assess cognitive impairment in Parkinson's disease? |
title_sort |
Can the CERAD neuropsychological battery be used to assess cognitive impairment in Parkinson's disease? |
author |
Camargo,Carlos Henrique Ferreira |
author_facet |
Camargo,Carlos Henrique Ferreira Bronzini,Augusto Tolentino,Eduardo de Souza Medyk,Camila Schultz-Pereira,Gustavo Leopold |
author_role |
author |
author2 |
Bronzini,Augusto Tolentino,Eduardo de Souza Medyk,Camila Schultz-Pereira,Gustavo Leopold |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Camargo,Carlos Henrique Ferreira Bronzini,Augusto Tolentino,Eduardo de Souza Medyk,Camila Schultz-Pereira,Gustavo Leopold |
dc.subject.por.fl_str_mv |
Parkinson's disease dementia cognition |
topic |
Parkinson's disease dementia cognition |
description |
ABSTRACT The Consortium to Establish a Registry for Alzheimer's Disease (CERAD) neuropsychological battery was created to assess cognitive impairment in Alzheimer's disease (AD) but it is widely-used for various dementias. The aim of this study was to analyze the efficacy of using the CERAD battery in the assessment of patients with Parkinson's disease. Forty-nine patients with Parkinson's disease were divided into two groups (one with dementia and one without) using the Movement Disorder Society criteria for Parkinson's disease dementia. Cognitive deficits were assessed with the Clinical Dementia Rating Scale as the gold standard, and the CERAD. The ROC curve for the CERAD battery had an area under the curve = 0.989 (95% CI = 0.967 – 1, p<0.0001). Among the CERAD subtests, verbal fluency had the worst accuracy, and word list learning had the best accuracy. Despite the limits of this study, the CERAD battery can be efficient for assessment of cognitive deficits in Parkinson's disease patients. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000300145 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000300145 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282x20180003 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.76 n.3 2018 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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1754212783676719104 |