Cerebrospinal fluid analysis: current diagnostic methods in central nervous system infectious diseases

Detalhes bibliográficos
Autor(a) principal: Gomes,Hélio Rodrigues
Data de Publicação: 2022
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2022000700290
Resumo: ABSTRACT Cerebrospinal fluid (CSF) analysis is an important diagnostic tool for many conditions affecting the central nervous system (CNS), especially CNS infectious diseases. Despite its low specificity, CSF white blood cell counts, CSF protein levels, CSF serum glucose ratio and CSF lactate measurement are useful in differentiating infections caused by distinct groups of pathogens. CSF direct examination and cultures can identify causative organisms and antibiotic sensitivities as well. Adjunctive tests such as latex agglutination, different immunological assays and molecular reactions have great specificities and increasing sensitivities. In this article, some recent diagnostic methods applied to CSF analysis for frequent CNS infections are presented.
id ABNEURO-1_aa16669b897c2e5a6cd099b251d3cf80
oai_identifier_str oai:scielo:S0004-282X2022000700290
network_acronym_str ABNEURO-1
network_name_str Arquivos de neuro-psiquiatria (Online)
repository_id_str
spelling Cerebrospinal fluid analysis: current diagnostic methods in central nervous system infectious diseasesCerebrospinal FluidCentral Nervous System Bacterial InfectionsBiomarkersMetagenomicsNeurosyphilisMeningoencephalitisABSTRACT Cerebrospinal fluid (CSF) analysis is an important diagnostic tool for many conditions affecting the central nervous system (CNS), especially CNS infectious diseases. Despite its low specificity, CSF white blood cell counts, CSF protein levels, CSF serum glucose ratio and CSF lactate measurement are useful in differentiating infections caused by distinct groups of pathogens. CSF direct examination and cultures can identify causative organisms and antibiotic sensitivities as well. Adjunctive tests such as latex agglutination, different immunological assays and molecular reactions have great specificities and increasing sensitivities. In this article, some recent diagnostic methods applied to CSF analysis for frequent CNS infections are presented.Academia Brasileira de Neurologia - ABNEURO2022-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2022000700290Arquivos de Neuro-Psiquiatria v.80 n.5 suppl.1 2022reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x-anp-2022-s114info:eu-repo/semantics/openAccessGomes,Hélio Rodrigueseng2022-08-16T00:00:00Zoai:scielo:S0004-282X2022000700290Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2022-08-16T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Cerebrospinal fluid analysis: current diagnostic methods in central nervous system infectious diseases
title Cerebrospinal fluid analysis: current diagnostic methods in central nervous system infectious diseases
spellingShingle Cerebrospinal fluid analysis: current diagnostic methods in central nervous system infectious diseases
Gomes,Hélio Rodrigues
Cerebrospinal Fluid
Central Nervous System Bacterial Infections
Biomarkers
Metagenomics
Neurosyphilis
Meningoencephalitis
title_short Cerebrospinal fluid analysis: current diagnostic methods in central nervous system infectious diseases
title_full Cerebrospinal fluid analysis: current diagnostic methods in central nervous system infectious diseases
title_fullStr Cerebrospinal fluid analysis: current diagnostic methods in central nervous system infectious diseases
title_full_unstemmed Cerebrospinal fluid analysis: current diagnostic methods in central nervous system infectious diseases
title_sort Cerebrospinal fluid analysis: current diagnostic methods in central nervous system infectious diseases
author Gomes,Hélio Rodrigues
author_facet Gomes,Hélio Rodrigues
author_role author
dc.contributor.author.fl_str_mv Gomes,Hélio Rodrigues
dc.subject.por.fl_str_mv Cerebrospinal Fluid
Central Nervous System Bacterial Infections
Biomarkers
Metagenomics
Neurosyphilis
Meningoencephalitis
topic Cerebrospinal Fluid
Central Nervous System Bacterial Infections
Biomarkers
Metagenomics
Neurosyphilis
Meningoencephalitis
description ABSTRACT Cerebrospinal fluid (CSF) analysis is an important diagnostic tool for many conditions affecting the central nervous system (CNS), especially CNS infectious diseases. Despite its low specificity, CSF white blood cell counts, CSF protein levels, CSF serum glucose ratio and CSF lactate measurement are useful in differentiating infections caused by distinct groups of pathogens. CSF direct examination and cultures can identify causative organisms and antibiotic sensitivities as well. Adjunctive tests such as latex agglutination, different immunological assays and molecular reactions have great specificities and increasing sensitivities. In this article, some recent diagnostic methods applied to CSF analysis for frequent CNS infections are presented.
publishDate 2022
dc.date.none.fl_str_mv 2022-05-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2022000700290
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2022000700290
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0004-282x-anp-2022-s114
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.80 n.5 suppl.1 2022
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
_version_ 1754212791833591808

Registros relacionados