Treatment of ischemic stroke with r-tPA: implementation challenges in a tertiary hospital in Brazil

Detalhes bibliográficos
Autor(a) principal: Tosta,Elza Dias
Data de Publicação: 2014
Outros Autores: Rebello,Letícia Costa, Almeida,Soraya Soares, Neiva,Márcia Silva Santos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000500368
Resumo: Purpose:This paper presents the initial experience with thrombolysis for acute ischaemic stroke at Hospital de Base do Distrito Federal (HBDF), Brazil, and the difficulties associated with the implementation of this treatment.Method:A retrospective study was performed using the medical records of all patients with acute stroke who were treated with intravenous alteplase in our department, between May 2011 and April 2012.Results:The thrombolytic therapy was administered to 32 patients. The mean time between the ictus and the start of stroke therapy start was 195 (60-270) minutes. Sixteen patients demonstrated a significant clinical improvement (decrease in National Institute Health Stroke Scale [NIHSS] score≥4 points in 24 hours); 6 patients were discharged with an NIHSS score of 0 and 2 demonstrated haemorrhagic transformation.Conclusions:The results of our study are similar to those reported in the literature, although we have been dealing with difficulties, such as the lack of a stroke unit.
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spelling Treatment of ischemic stroke with r-tPA: implementation challenges in a tertiary hospital in Brazilstrokethrombolytic therapytissue plasminogen activatorPurpose:This paper presents the initial experience with thrombolysis for acute ischaemic stroke at Hospital de Base do Distrito Federal (HBDF), Brazil, and the difficulties associated with the implementation of this treatment.Method:A retrospective study was performed using the medical records of all patients with acute stroke who were treated with intravenous alteplase in our department, between May 2011 and April 2012.Results:The thrombolytic therapy was administered to 32 patients. The mean time between the ictus and the start of stroke therapy start was 195 (60-270) minutes. Sixteen patients demonstrated a significant clinical improvement (decrease in National Institute Health Stroke Scale [NIHSS] score≥4 points in 24 hours); 6 patients were discharged with an NIHSS score of 0 and 2 demonstrated haemorrhagic transformation.Conclusions:The results of our study are similar to those reported in the literature, although we have been dealing with difficulties, such as the lack of a stroke unit.Academia Brasileira de Neurologia - ABNEURO2014-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000500368Arquivos de Neuro-Psiquiatria v.72 n.5 2014reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282X20140021info:eu-repo/semantics/openAccessTosta,Elza DiasRebello,Letícia CostaAlmeida,Soraya SoaresNeiva,Márcia Silva Santoseng2015-10-08T00:00:00Zoai:scielo:S0004-282X2014000500368Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2015-10-08T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Treatment of ischemic stroke with r-tPA: implementation challenges in a tertiary hospital in Brazil
title Treatment of ischemic stroke with r-tPA: implementation challenges in a tertiary hospital in Brazil
spellingShingle Treatment of ischemic stroke with r-tPA: implementation challenges in a tertiary hospital in Brazil
Tosta,Elza Dias
stroke
thrombolytic therapy
tissue plasminogen activator
title_short Treatment of ischemic stroke with r-tPA: implementation challenges in a tertiary hospital in Brazil
title_full Treatment of ischemic stroke with r-tPA: implementation challenges in a tertiary hospital in Brazil
title_fullStr Treatment of ischemic stroke with r-tPA: implementation challenges in a tertiary hospital in Brazil
title_full_unstemmed Treatment of ischemic stroke with r-tPA: implementation challenges in a tertiary hospital in Brazil
title_sort Treatment of ischemic stroke with r-tPA: implementation challenges in a tertiary hospital in Brazil
author Tosta,Elza Dias
author_facet Tosta,Elza Dias
Rebello,Letícia Costa
Almeida,Soraya Soares
Neiva,Márcia Silva Santos
author_role author
author2 Rebello,Letícia Costa
Almeida,Soraya Soares
Neiva,Márcia Silva Santos
author2_role author
author
author
dc.contributor.author.fl_str_mv Tosta,Elza Dias
Rebello,Letícia Costa
Almeida,Soraya Soares
Neiva,Márcia Silva Santos
dc.subject.por.fl_str_mv stroke
thrombolytic therapy
tissue plasminogen activator
topic stroke
thrombolytic therapy
tissue plasminogen activator
description Purpose:This paper presents the initial experience with thrombolysis for acute ischaemic stroke at Hospital de Base do Distrito Federal (HBDF), Brazil, and the difficulties associated with the implementation of this treatment.Method:A retrospective study was performed using the medical records of all patients with acute stroke who were treated with intravenous alteplase in our department, between May 2011 and April 2012.Results:The thrombolytic therapy was administered to 32 patients. The mean time between the ictus and the start of stroke therapy start was 195 (60-270) minutes. Sixteen patients demonstrated a significant clinical improvement (decrease in National Institute Health Stroke Scale [NIHSS] score≥4 points in 24 hours); 6 patients were discharged with an NIHSS score of 0 and 2 demonstrated haemorrhagic transformation.Conclusions:The results of our study are similar to those reported in the literature, although we have been dealing with difficulties, such as the lack of a stroke unit.
publishDate 2014
dc.date.none.fl_str_mv 2014-05-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000500368
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000500368
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0004-282X20140021
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.72 n.5 2014
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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