Use of non-invasive stimulation in movement disorders: a critical review
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021000700630 |
Resumo: | Abstract Background: Noninvasive stimulation has been widely used in the past 30 years to study and treat a large number of neurological diseases, including movement disorders. Objective: In this critical review, we illustrate the rationale for use of these techniques in movement disorders and summarize the best medical evidence based on the main clinical trials performed to date. Methods: A nationally representative group of experts performed a comprehensive review of the literature in order to analyze the key clinical decision-making factors driving transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) in movement disorders. Classes of evidence and recommendations were described for each disease. Results: Despite unavoidable heterogeneities and low effect size, TMS is likely to be effective for treating motor symptoms and depression in Parkinson’s disease (PD). The efficacy in other movement disorders is unclear. TMS is possibly effective for focal hand dystonia, essential tremor and cerebellar ataxia. Additionally, it is likely to be ineffective in reducing tics in Tourette syndrome. Lastly, tDCS is likely to be effective in improving gait in PD. Conclusions: There is encouraging evidence for the use of noninvasive stimulation on a subset of symptoms in selected movement disorders, although the means to optimize protocols for improving positive outcomes in routine clinical practice remain undetermined. Similarly, the best stimulation paradigms and responder profile need to be investigated in large clinical trials with established therapeutic and assessment paradigms that could also allow genuine long-term benefits to be determined. |
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Use of non-invasive stimulation in movement disorders: a critical reviewParkinson’s DiseaseMovement DisordersTranscranial Direct Current StimulationTranscranial Magnetic StimulationAbstract Background: Noninvasive stimulation has been widely used in the past 30 years to study and treat a large number of neurological diseases, including movement disorders. Objective: In this critical review, we illustrate the rationale for use of these techniques in movement disorders and summarize the best medical evidence based on the main clinical trials performed to date. Methods: A nationally representative group of experts performed a comprehensive review of the literature in order to analyze the key clinical decision-making factors driving transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) in movement disorders. Classes of evidence and recommendations were described for each disease. Results: Despite unavoidable heterogeneities and low effect size, TMS is likely to be effective for treating motor symptoms and depression in Parkinson’s disease (PD). The efficacy in other movement disorders is unclear. TMS is possibly effective for focal hand dystonia, essential tremor and cerebellar ataxia. Additionally, it is likely to be ineffective in reducing tics in Tourette syndrome. Lastly, tDCS is likely to be effective in improving gait in PD. Conclusions: There is encouraging evidence for the use of noninvasive stimulation on a subset of symptoms in selected movement disorders, although the means to optimize protocols for improving positive outcomes in routine clinical practice remain undetermined. Similarly, the best stimulation paradigms and responder profile need to be investigated in large clinical trials with established therapeutic and assessment paradigms that could also allow genuine long-term benefits to be determined.Academia Brasileira de Neurologia - ABNEURO2021-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021000700630Arquivos de Neuro-Psiquiatria v.79 n.7 2021reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x-anp-2020-0381info:eu-repo/semantics/openAccessGodeiro,ClecioFrança,CarinaCarra,Rafael BernhartSaba,FelipeSaba,RobertaMaia,DéboraBrandão,PedroAllam,NasserRieder,Carlos R. M.Freitas,Fernando CiniCapato,TamineSpitz,MarianaFaria,Danilo Donizete deCordellini,MarcelaVeiga,Beatriz A. A. G.Rocha,Maria Sheila G.Maciel,RicardoMelo,Lucio B. DeMöller,Patricia D. S.R. R. Júnior,MagnoFornari,Luís H. T.Mantese,Carlos E.Barbosa,Egberto ReisMunhoz,Renato P.Coletta,Marcus Vinicius DellaCury,Rubens Gisberteng2021-08-23T00:00:00Zoai:scielo:S0004-282X2021000700630Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2021-08-23T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Use of non-invasive stimulation in movement disorders: a critical review |
title |
Use of non-invasive stimulation in movement disorders: a critical review |
spellingShingle |
Use of non-invasive stimulation in movement disorders: a critical review Godeiro,Clecio Parkinson’s Disease Movement Disorders Transcranial Direct Current Stimulation Transcranial Magnetic Stimulation |
title_short |
Use of non-invasive stimulation in movement disorders: a critical review |
title_full |
Use of non-invasive stimulation in movement disorders: a critical review |
title_fullStr |
Use of non-invasive stimulation in movement disorders: a critical review |
title_full_unstemmed |
Use of non-invasive stimulation in movement disorders: a critical review |
title_sort |
Use of non-invasive stimulation in movement disorders: a critical review |
author |
Godeiro,Clecio |
author_facet |
Godeiro,Clecio França,Carina Carra,Rafael Bernhart Saba,Felipe Saba,Roberta Maia,Débora Brandão,Pedro Allam,Nasser Rieder,Carlos R. M. Freitas,Fernando Cini Capato,Tamine Spitz,Mariana Faria,Danilo Donizete de Cordellini,Marcela Veiga,Beatriz A. A. G. Rocha,Maria Sheila G. Maciel,Ricardo Melo,Lucio B. De Möller,Patricia D. S. R. R. Júnior,Magno Fornari,Luís H. T. Mantese,Carlos E. Barbosa,Egberto Reis Munhoz,Renato P. Coletta,Marcus Vinicius Della Cury,Rubens Gisbert |
author_role |
author |
author2 |
França,Carina Carra,Rafael Bernhart Saba,Felipe Saba,Roberta Maia,Débora Brandão,Pedro Allam,Nasser Rieder,Carlos R. M. Freitas,Fernando Cini Capato,Tamine Spitz,Mariana Faria,Danilo Donizete de Cordellini,Marcela Veiga,Beatriz A. A. G. Rocha,Maria Sheila G. Maciel,Ricardo Melo,Lucio B. De Möller,Patricia D. S. R. R. Júnior,Magno Fornari,Luís H. T. Mantese,Carlos E. Barbosa,Egberto Reis Munhoz,Renato P. Coletta,Marcus Vinicius Della Cury,Rubens Gisbert |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Godeiro,Clecio França,Carina Carra,Rafael Bernhart Saba,Felipe Saba,Roberta Maia,Débora Brandão,Pedro Allam,Nasser Rieder,Carlos R. M. Freitas,Fernando Cini Capato,Tamine Spitz,Mariana Faria,Danilo Donizete de Cordellini,Marcela Veiga,Beatriz A. A. G. Rocha,Maria Sheila G. Maciel,Ricardo Melo,Lucio B. De Möller,Patricia D. S. R. R. Júnior,Magno Fornari,Luís H. T. Mantese,Carlos E. Barbosa,Egberto Reis Munhoz,Renato P. Coletta,Marcus Vinicius Della Cury,Rubens Gisbert |
dc.subject.por.fl_str_mv |
Parkinson’s Disease Movement Disorders Transcranial Direct Current Stimulation Transcranial Magnetic Stimulation |
topic |
Parkinson’s Disease Movement Disorders Transcranial Direct Current Stimulation Transcranial Magnetic Stimulation |
description |
Abstract Background: Noninvasive stimulation has been widely used in the past 30 years to study and treat a large number of neurological diseases, including movement disorders. Objective: In this critical review, we illustrate the rationale for use of these techniques in movement disorders and summarize the best medical evidence based on the main clinical trials performed to date. Methods: A nationally representative group of experts performed a comprehensive review of the literature in order to analyze the key clinical decision-making factors driving transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) in movement disorders. Classes of evidence and recommendations were described for each disease. Results: Despite unavoidable heterogeneities and low effect size, TMS is likely to be effective for treating motor symptoms and depression in Parkinson’s disease (PD). The efficacy in other movement disorders is unclear. TMS is possibly effective for focal hand dystonia, essential tremor and cerebellar ataxia. Additionally, it is likely to be ineffective in reducing tics in Tourette syndrome. Lastly, tDCS is likely to be effective in improving gait in PD. Conclusions: There is encouraging evidence for the use of noninvasive stimulation on a subset of symptoms in selected movement disorders, although the means to optimize protocols for improving positive outcomes in routine clinical practice remain undetermined. Similarly, the best stimulation paradigms and responder profile need to be investigated in large clinical trials with established therapeutic and assessment paradigms that could also allow genuine long-term benefits to be determined. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-07-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021000700630 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021000700630 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282x-anp-2020-0381 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.79 n.7 2021 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
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