Primary progressive aphasia: analisys of 16 cases

Detalhes bibliográficos
Autor(a) principal: Radanovic,Márcia
Data de Publicação: 2001
Outros Autores: Senaha,Mirna Lie Hosogi, Mansur,Letícia Lessa, Nitrini,Ricardo, Bahia,Valéria Santoro, Carthery,Maria Teresa, Aires,Flávia Nóbrega Freire, Mathias,Sandra Christina, Caramelli,Paulo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000400006
Resumo: Primary progressive aphasia (PPA) is an intriguing syndrome, showing some peculiar aspects that differentiate it from classical aphasic pictures caused by focal cerebral lesions or dementia. The slow and progressive deterioration of language occurring in these cases provides an interesting model to better understand the mechanisms involved in the linguistic process. We describe clinical and neuroimaging aspects found in 16 cases of PPA. Our patients underwent language and neuropsychological evaluation, magnetic resonance imaging (MRI) and single photon emission computerized tomography (SPECT). We observed a clear distinction in oral expression patterns; patients were classified as fluent and nonfluent. Anomia was the earliest and most evident symptom in both groups. Neuroimaging pointed to SPECT as a valuable instrument in guiding the differential diagnosis, as well as in making useful clinical and anatomical correlations. This report and a comparison to literature are an attempt to contribute to a better understanding of PPA.
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spelling Primary progressive aphasia: analisys of 16 casesprimary progressive aphasiafocal cortical degenerationcerebral perfusionneuroimagingPrimary progressive aphasia (PPA) is an intriguing syndrome, showing some peculiar aspects that differentiate it from classical aphasic pictures caused by focal cerebral lesions or dementia. The slow and progressive deterioration of language occurring in these cases provides an interesting model to better understand the mechanisms involved in the linguistic process. We describe clinical and neuroimaging aspects found in 16 cases of PPA. Our patients underwent language and neuropsychological evaluation, magnetic resonance imaging (MRI) and single photon emission computerized tomography (SPECT). We observed a clear distinction in oral expression patterns; patients were classified as fluent and nonfluent. Anomia was the earliest and most evident symptom in both groups. Neuroimaging pointed to SPECT as a valuable instrument in guiding the differential diagnosis, as well as in making useful clinical and anatomical correlations. This report and a comparison to literature are an attempt to contribute to a better understanding of PPA.Academia Brasileira de Neurologia - ABNEURO2001-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000400006Arquivos de Neuro-Psiquiatria v.59 n.3A 2001reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2001000400006info:eu-repo/semantics/openAccessRadanovic,MárciaSenaha,Mirna Lie HosogiMansur,Letícia LessaNitrini,RicardoBahia,Valéria SantoroCarthery,Maria TeresaAires,Flávia Nóbrega FreireMathias,Sandra ChristinaCaramelli,Pauloeng2001-10-04T00:00:00Zoai:scielo:S0004-282X2001000400006Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2001-10-04T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Primary progressive aphasia: analisys of 16 cases
title Primary progressive aphasia: analisys of 16 cases
spellingShingle Primary progressive aphasia: analisys of 16 cases
Radanovic,Márcia
primary progressive aphasia
focal cortical degeneration
cerebral perfusion
neuroimaging
title_short Primary progressive aphasia: analisys of 16 cases
title_full Primary progressive aphasia: analisys of 16 cases
title_fullStr Primary progressive aphasia: analisys of 16 cases
title_full_unstemmed Primary progressive aphasia: analisys of 16 cases
title_sort Primary progressive aphasia: analisys of 16 cases
author Radanovic,Márcia
author_facet Radanovic,Márcia
Senaha,Mirna Lie Hosogi
Mansur,Letícia Lessa
Nitrini,Ricardo
Bahia,Valéria Santoro
Carthery,Maria Teresa
Aires,Flávia Nóbrega Freire
Mathias,Sandra Christina
Caramelli,Paulo
author_role author
author2 Senaha,Mirna Lie Hosogi
Mansur,Letícia Lessa
Nitrini,Ricardo
Bahia,Valéria Santoro
Carthery,Maria Teresa
Aires,Flávia Nóbrega Freire
Mathias,Sandra Christina
Caramelli,Paulo
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Radanovic,Márcia
Senaha,Mirna Lie Hosogi
Mansur,Letícia Lessa
Nitrini,Ricardo
Bahia,Valéria Santoro
Carthery,Maria Teresa
Aires,Flávia Nóbrega Freire
Mathias,Sandra Christina
Caramelli,Paulo
dc.subject.por.fl_str_mv primary progressive aphasia
focal cortical degeneration
cerebral perfusion
neuroimaging
topic primary progressive aphasia
focal cortical degeneration
cerebral perfusion
neuroimaging
description Primary progressive aphasia (PPA) is an intriguing syndrome, showing some peculiar aspects that differentiate it from classical aphasic pictures caused by focal cerebral lesions or dementia. The slow and progressive deterioration of language occurring in these cases provides an interesting model to better understand the mechanisms involved in the linguistic process. We describe clinical and neuroimaging aspects found in 16 cases of PPA. Our patients underwent language and neuropsychological evaluation, magnetic resonance imaging (MRI) and single photon emission computerized tomography (SPECT). We observed a clear distinction in oral expression patterns; patients were classified as fluent and nonfluent. Anomia was the earliest and most evident symptom in both groups. Neuroimaging pointed to SPECT as a valuable instrument in guiding the differential diagnosis, as well as in making useful clinical and anatomical correlations. This report and a comparison to literature are an attempt to contribute to a better understanding of PPA.
publishDate 2001
dc.date.none.fl_str_mv 2001-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000400006
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000400006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X2001000400006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.59 n.3A 2001
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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