Neuromodulatory effects of caffeine and bromazepam on visual event-related potential (P300): a comparative study

Detalhes bibliográficos
Autor(a) principal: Montenegro,Mariana
Data de Publicação: 2005
Outros Autores: Veiga,Heloisa, Deslandes,Andréa, Cagy,Maurício, McDowell,Kaleb, Pompeu,Fernando, Piedade,Roberto, Ribeiro,Pedro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2005000300009
Resumo: The P300 component of the event-related potential (ERP) is a general measurement of "cognitive efficiency". It is an index of the ability of an individual's central nervous system (CNS) to process incoming information. OBJECTIVE: To compare the neuromodulatory effects of caffeine and bromazepam on the visual ERP (P300), in relation to a P300 normative database. METHOD: 15 right-handed individuals (7 male and 8 female), between 20 and 30 years of age, healthy, free of any cognitive impairment and not making use of psychoactive substances were studied. Participants were submitted to a visual discrimination task, which employed the "oddball" paradigm, after the administration of caffeine and bromazepam, in a randomized, double-blind design. RESULTS: Statistically significant differences were observed when the caffeine and bromazepam conditions were compared to the normative database. CONCLUSION: The present results suggest that caffeine and bromazepam have distinct modulatory effects on CNS functioning.
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spelling Neuromodulatory effects of caffeine and bromazepam on visual event-related potential (P300): a comparative studyevent-related potentialP300caffeinebromazepamThe P300 component of the event-related potential (ERP) is a general measurement of "cognitive efficiency". It is an index of the ability of an individual's central nervous system (CNS) to process incoming information. OBJECTIVE: To compare the neuromodulatory effects of caffeine and bromazepam on the visual ERP (P300), in relation to a P300 normative database. METHOD: 15 right-handed individuals (7 male and 8 female), between 20 and 30 years of age, healthy, free of any cognitive impairment and not making use of psychoactive substances were studied. Participants were submitted to a visual discrimination task, which employed the "oddball" paradigm, after the administration of caffeine and bromazepam, in a randomized, double-blind design. RESULTS: Statistically significant differences were observed when the caffeine and bromazepam conditions were compared to the normative database. CONCLUSION: The present results suggest that caffeine and bromazepam have distinct modulatory effects on CNS functioning.Academia Brasileira de Neurologia - ABNEURO2005-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2005000300009Arquivos de Neuro-Psiquiatria v.63 n.2b 2005reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2005000300009info:eu-repo/semantics/openAccessMontenegro,MarianaVeiga,HeloisaDeslandes,AndréaCagy,MaurícioMcDowell,KalebPompeu,FernandoPiedade,RobertoRibeiro,Pedroeng2005-07-25T00:00:00Zoai:scielo:S0004-282X2005000300009Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2005-07-25T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Neuromodulatory effects of caffeine and bromazepam on visual event-related potential (P300): a comparative study
title Neuromodulatory effects of caffeine and bromazepam on visual event-related potential (P300): a comparative study
spellingShingle Neuromodulatory effects of caffeine and bromazepam on visual event-related potential (P300): a comparative study
Montenegro,Mariana
event-related potential
P300
caffeine
bromazepam
title_short Neuromodulatory effects of caffeine and bromazepam on visual event-related potential (P300): a comparative study
title_full Neuromodulatory effects of caffeine and bromazepam on visual event-related potential (P300): a comparative study
title_fullStr Neuromodulatory effects of caffeine and bromazepam on visual event-related potential (P300): a comparative study
title_full_unstemmed Neuromodulatory effects of caffeine and bromazepam on visual event-related potential (P300): a comparative study
title_sort Neuromodulatory effects of caffeine and bromazepam on visual event-related potential (P300): a comparative study
author Montenegro,Mariana
author_facet Montenegro,Mariana
Veiga,Heloisa
Deslandes,Andréa
Cagy,Maurício
McDowell,Kaleb
Pompeu,Fernando
Piedade,Roberto
Ribeiro,Pedro
author_role author
author2 Veiga,Heloisa
Deslandes,Andréa
Cagy,Maurício
McDowell,Kaleb
Pompeu,Fernando
Piedade,Roberto
Ribeiro,Pedro
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Montenegro,Mariana
Veiga,Heloisa
Deslandes,Andréa
Cagy,Maurício
McDowell,Kaleb
Pompeu,Fernando
Piedade,Roberto
Ribeiro,Pedro
dc.subject.por.fl_str_mv event-related potential
P300
caffeine
bromazepam
topic event-related potential
P300
caffeine
bromazepam
description The P300 component of the event-related potential (ERP) is a general measurement of "cognitive efficiency". It is an index of the ability of an individual's central nervous system (CNS) to process incoming information. OBJECTIVE: To compare the neuromodulatory effects of caffeine and bromazepam on the visual ERP (P300), in relation to a P300 normative database. METHOD: 15 right-handed individuals (7 male and 8 female), between 20 and 30 years of age, healthy, free of any cognitive impairment and not making use of psychoactive substances were studied. Participants were submitted to a visual discrimination task, which employed the "oddball" paradigm, after the administration of caffeine and bromazepam, in a randomized, double-blind design. RESULTS: Statistically significant differences were observed when the caffeine and bromazepam conditions were compared to the normative database. CONCLUSION: The present results suggest that caffeine and bromazepam have distinct modulatory effects on CNS functioning.
publishDate 2005
dc.date.none.fl_str_mv 2005-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2005000300009
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2005000300009
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X2005000300009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.63 n.2b 2005
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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