Apert syndrome: factors involved in the cognitive development
Autor(a) principal: | |
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Data de Publicação: | 2005 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2005000600011 |
Resumo: | Apert syndrome is characterized by craniosynostosis, symmetric syndactyly and other systemic malformations, with mental retardation usually present. The objective of this study was to correlate brain malformations and timing for surgery with neuropsychological evaluation. We also tried to determine other relevant aspects involved in cognitive development of these patients such as social classification of families and parents education. Eighteen patients with Apert syndrome were studied, whose ages were between 14 and 322 months. Brain abnormalities were observed in 55.6% of them. The intelligence quotient or developmental quotient values observed were between 45 and 108. Mental development was related to the quality of family environment and parents education. Mental development was not correlated to brain malformation or age at time of operation. In conclusion, quality of family environment was the most significant factor directly involved in mental development of patients with Apert syndrome. |
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Apert syndrome: factors involved in the cognitive developmentApert syndromemental developmentmagnetic resonanceApert syndrome is characterized by craniosynostosis, symmetric syndactyly and other systemic malformations, with mental retardation usually present. The objective of this study was to correlate brain malformations and timing for surgery with neuropsychological evaluation. We also tried to determine other relevant aspects involved in cognitive development of these patients such as social classification of families and parents education. Eighteen patients with Apert syndrome were studied, whose ages were between 14 and 322 months. Brain abnormalities were observed in 55.6% of them. The intelligence quotient or developmental quotient values observed were between 45 and 108. Mental development was related to the quality of family environment and parents education. Mental development was not correlated to brain malformation or age at time of operation. In conclusion, quality of family environment was the most significant factor directly involved in mental development of patients with Apert syndrome.Academia Brasileira de Neurologia - ABNEURO2005-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2005000600011Arquivos de Neuro-Psiquiatria v.63 n.4 2005reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2005000600011info:eu-repo/semantics/openAccessYacubian-Fernandes,AdrianoPalhares,AristidesGiglio,AlcirGabarra,Roberto C.Zanini,SilvioPortela,LuisSilva,Mateus ViolinPerosa,Gimol BezaquenAbramides,DagmaPlese,José Píndaro P.eng2006-01-09T00:00:00Zoai:scielo:S0004-282X2005000600011Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2006-01-09T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Apert syndrome: factors involved in the cognitive development |
title |
Apert syndrome: factors involved in the cognitive development |
spellingShingle |
Apert syndrome: factors involved in the cognitive development Yacubian-Fernandes,Adriano Apert syndrome mental development magnetic resonance |
title_short |
Apert syndrome: factors involved in the cognitive development |
title_full |
Apert syndrome: factors involved in the cognitive development |
title_fullStr |
Apert syndrome: factors involved in the cognitive development |
title_full_unstemmed |
Apert syndrome: factors involved in the cognitive development |
title_sort |
Apert syndrome: factors involved in the cognitive development |
author |
Yacubian-Fernandes,Adriano |
author_facet |
Yacubian-Fernandes,Adriano Palhares,Aristides Giglio,Alcir Gabarra,Roberto C. Zanini,Silvio Portela,Luis Silva,Mateus Violin Perosa,Gimol Bezaquen Abramides,Dagma Plese,José Píndaro P. |
author_role |
author |
author2 |
Palhares,Aristides Giglio,Alcir Gabarra,Roberto C. Zanini,Silvio Portela,Luis Silva,Mateus Violin Perosa,Gimol Bezaquen Abramides,Dagma Plese,José Píndaro P. |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Yacubian-Fernandes,Adriano Palhares,Aristides Giglio,Alcir Gabarra,Roberto C. Zanini,Silvio Portela,Luis Silva,Mateus Violin Perosa,Gimol Bezaquen Abramides,Dagma Plese,José Píndaro P. |
dc.subject.por.fl_str_mv |
Apert syndrome mental development magnetic resonance |
topic |
Apert syndrome mental development magnetic resonance |
description |
Apert syndrome is characterized by craniosynostosis, symmetric syndactyly and other systemic malformations, with mental retardation usually present. The objective of this study was to correlate brain malformations and timing for surgery with neuropsychological evaluation. We also tried to determine other relevant aspects involved in cognitive development of these patients such as social classification of families and parents education. Eighteen patients with Apert syndrome were studied, whose ages were between 14 and 322 months. Brain abnormalities were observed in 55.6% of them. The intelligence quotient or developmental quotient values observed were between 45 and 108. Mental development was related to the quality of family environment and parents education. Mental development was not correlated to brain malformation or age at time of operation. In conclusion, quality of family environment was the most significant factor directly involved in mental development of patients with Apert syndrome. |
publishDate |
2005 |
dc.date.none.fl_str_mv |
2005-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2005000600011 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2005000600011 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-282X2005000600011 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.63 n.4 2005 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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1754212759166255104 |