Cerebral hemodynamic and metabolic changes in fulminant hepatic failure

Detalhes bibliográficos
Autor(a) principal: Paschoal Junior,Fernando Mendes
Data de Publicação: 2017
Outros Autores: Nogueira,Ricardo de Carvalho, Oliveira,Marcelo de Lima, Paschoal,Eric Homero Albuquerque, Teixeira,Manoel Jacobsen, D’Albuquerque,Luiz Augusto Carneiro, Bor-Seng-Shu,Edson
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000700470
Resumo: ABSTRACT Intracranial hypertension and brain swelling are a major cause of morbidity and mortality of patients suffering from fulminant hepatic failure (FHF). The pathogenesis of these complications has been investigated in man, in experimental models and in isolated cell systems. Currently, the mechanism underlying cerebral edema and intracranial hypertension in the presence of FHF is multi-factorial in etiology and only partially understood. The aim of this paper is to review the pathophysiology of cerebral hemodynamic and metabolism changes in FHF in order to improve understanding of intracranial dynamics complication in FHF.
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spelling Cerebral hemodynamic and metabolic changes in fulminant hepatic failurehepatic insufficiencyintracranial hypertensionbrain edemaABSTRACT Intracranial hypertension and brain swelling are a major cause of morbidity and mortality of patients suffering from fulminant hepatic failure (FHF). The pathogenesis of these complications has been investigated in man, in experimental models and in isolated cell systems. Currently, the mechanism underlying cerebral edema and intracranial hypertension in the presence of FHF is multi-factorial in etiology and only partially understood. The aim of this paper is to review the pathophysiology of cerebral hemodynamic and metabolism changes in FHF in order to improve understanding of intracranial dynamics complication in FHF.Academia Brasileira de Neurologia - ABNEURO2017-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000700470Arquivos de Neuro-Psiquiatria v.75 n.7 2017reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x20170076info:eu-repo/semantics/openAccessPaschoal Junior,Fernando MendesNogueira,Ricardo de CarvalhoOliveira,Marcelo de LimaPaschoal,Eric Homero AlbuquerqueTeixeira,Manoel JacobsenD’Albuquerque,Luiz Augusto CarneiroBor-Seng-Shu,Edsoneng2018-04-02T00:00:00Zoai:scielo:S0004-282X2017000700470Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2018-04-02T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Cerebral hemodynamic and metabolic changes in fulminant hepatic failure
title Cerebral hemodynamic and metabolic changes in fulminant hepatic failure
spellingShingle Cerebral hemodynamic and metabolic changes in fulminant hepatic failure
Paschoal Junior,Fernando Mendes
hepatic insufficiency
intracranial hypertension
brain edema
title_short Cerebral hemodynamic and metabolic changes in fulminant hepatic failure
title_full Cerebral hemodynamic and metabolic changes in fulminant hepatic failure
title_fullStr Cerebral hemodynamic and metabolic changes in fulminant hepatic failure
title_full_unstemmed Cerebral hemodynamic and metabolic changes in fulminant hepatic failure
title_sort Cerebral hemodynamic and metabolic changes in fulminant hepatic failure
author Paschoal Junior,Fernando Mendes
author_facet Paschoal Junior,Fernando Mendes
Nogueira,Ricardo de Carvalho
Oliveira,Marcelo de Lima
Paschoal,Eric Homero Albuquerque
Teixeira,Manoel Jacobsen
D’Albuquerque,Luiz Augusto Carneiro
Bor-Seng-Shu,Edson
author_role author
author2 Nogueira,Ricardo de Carvalho
Oliveira,Marcelo de Lima
Paschoal,Eric Homero Albuquerque
Teixeira,Manoel Jacobsen
D’Albuquerque,Luiz Augusto Carneiro
Bor-Seng-Shu,Edson
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Paschoal Junior,Fernando Mendes
Nogueira,Ricardo de Carvalho
Oliveira,Marcelo de Lima
Paschoal,Eric Homero Albuquerque
Teixeira,Manoel Jacobsen
D’Albuquerque,Luiz Augusto Carneiro
Bor-Seng-Shu,Edson
dc.subject.por.fl_str_mv hepatic insufficiency
intracranial hypertension
brain edema
topic hepatic insufficiency
intracranial hypertension
brain edema
description ABSTRACT Intracranial hypertension and brain swelling are a major cause of morbidity and mortality of patients suffering from fulminant hepatic failure (FHF). The pathogenesis of these complications has been investigated in man, in experimental models and in isolated cell systems. Currently, the mechanism underlying cerebral edema and intracranial hypertension in the presence of FHF is multi-factorial in etiology and only partially understood. The aim of this paper is to review the pathophysiology of cerebral hemodynamic and metabolism changes in FHF in order to improve understanding of intracranial dynamics complication in FHF.
publishDate 2017
dc.date.none.fl_str_mv 2017-07-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000700470
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000700470
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0004-282x20170076
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.75 n.7 2017
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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