Selective therapeutic hypothermia: A review of invasive and noninvasive techniques

Detalhes bibliográficos
Autor(a) principal: Straus,David
Data de Publicação: 2011
Outros Autores: Prasad,Vinay, Munoz,Lorenzo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000700025
Resumo: OBJECTIVE: Therapeutic hypothermia is a promising treatment to prevent secondary neurologic injury. Clinical utility is limited by systemic complications of global hypothermia. Selective brain cooling remains a largely uninvestigated application. We review techniques of inducing selective brain cooling. METHOD: Literature review. RESULTS: Strategies of inducing selective brain cooling were divided between non-invasive and invasive techniques. Non-invasive techniques were surface cooling and cooling via the upper airway. Invasive cooling methods include transvascular and compartmental (epidural, subdural, subarachnoid and intraventricular) cooling methods to remove heat from the brain. CONCLUSION: Selective brain cooling may offer the best strategy for achieving hypothermic neuroprotection. Non-invasive strategies have proven disappointing in human trials. There is a paucity of human experiments using invasive methods of selective brain cooling. Further application of invasive cooling strategies is needed.
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spelling Selective therapeutic hypothermia: A review of invasive and noninvasive techniquestherapeutic hypothermiaselective brain coolingneuroprotectionisolated cerebral hypothermiaOBJECTIVE: Therapeutic hypothermia is a promising treatment to prevent secondary neurologic injury. Clinical utility is limited by systemic complications of global hypothermia. Selective brain cooling remains a largely uninvestigated application. We review techniques of inducing selective brain cooling. METHOD: Literature review. RESULTS: Strategies of inducing selective brain cooling were divided between non-invasive and invasive techniques. Non-invasive techniques were surface cooling and cooling via the upper airway. Invasive cooling methods include transvascular and compartmental (epidural, subdural, subarachnoid and intraventricular) cooling methods to remove heat from the brain. CONCLUSION: Selective brain cooling may offer the best strategy for achieving hypothermic neuroprotection. Non-invasive strategies have proven disappointing in human trials. There is a paucity of human experiments using invasive methods of selective brain cooling. Further application of invasive cooling strategies is needed.Academia Brasileira de Neurologia - ABNEURO2011-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000700025Arquivos de Neuro-Psiquiatria v.69 n.6 2011reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2011000700025info:eu-repo/semantics/openAccessStraus,DavidPrasad,VinayMunoz,Lorenzoeng2012-01-27T00:00:00Zoai:scielo:S0004-282X2011000700025Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2012-01-27T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Selective therapeutic hypothermia: A review of invasive and noninvasive techniques
title Selective therapeutic hypothermia: A review of invasive and noninvasive techniques
spellingShingle Selective therapeutic hypothermia: A review of invasive and noninvasive techniques
Straus,David
therapeutic hypothermia
selective brain cooling
neuroprotection
isolated cerebral hypothermia
title_short Selective therapeutic hypothermia: A review of invasive and noninvasive techniques
title_full Selective therapeutic hypothermia: A review of invasive and noninvasive techniques
title_fullStr Selective therapeutic hypothermia: A review of invasive and noninvasive techniques
title_full_unstemmed Selective therapeutic hypothermia: A review of invasive and noninvasive techniques
title_sort Selective therapeutic hypothermia: A review of invasive and noninvasive techniques
author Straus,David
author_facet Straus,David
Prasad,Vinay
Munoz,Lorenzo
author_role author
author2 Prasad,Vinay
Munoz,Lorenzo
author2_role author
author
dc.contributor.author.fl_str_mv Straus,David
Prasad,Vinay
Munoz,Lorenzo
dc.subject.por.fl_str_mv therapeutic hypothermia
selective brain cooling
neuroprotection
isolated cerebral hypothermia
topic therapeutic hypothermia
selective brain cooling
neuroprotection
isolated cerebral hypothermia
description OBJECTIVE: Therapeutic hypothermia is a promising treatment to prevent secondary neurologic injury. Clinical utility is limited by systemic complications of global hypothermia. Selective brain cooling remains a largely uninvestigated application. We review techniques of inducing selective brain cooling. METHOD: Literature review. RESULTS: Strategies of inducing selective brain cooling were divided between non-invasive and invasive techniques. Non-invasive techniques were surface cooling and cooling via the upper airway. Invasive cooling methods include transvascular and compartmental (epidural, subdural, subarachnoid and intraventricular) cooling methods to remove heat from the brain. CONCLUSION: Selective brain cooling may offer the best strategy for achieving hypothermic neuroprotection. Non-invasive strategies have proven disappointing in human trials. There is a paucity of human experiments using invasive methods of selective brain cooling. Further application of invasive cooling strategies is needed.
publishDate 2011
dc.date.none.fl_str_mv 2011-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000700025
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000700025
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X2011000700025
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.69 n.6 2011
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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