Osteonecrosis of the jaws in a patient with multiple myeloma - a case report

Detalhes bibliográficos
Autor(a) principal: Mendes, Vera Lúcia Duarte da Costa
Data de Publicação: 2018
Outros Autores: Paoli, Fabiana de, Hespanhol, Wagner
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Odontologia
Texto Completo: https://revista.aborj.org.br/index.php/rbo/article/view/1184
Resumo: Objective: tthis paper reports a case of osteonecrosis of the jaws associated with the use of intravenous bisphosphonates (BRONJ) after extraction of the maxillary right first and second molars. Case report: a 53-year-old male patient with diagnosis of multiple myeloma undergoing treatment at Arthur Siqueira Cavalcanti Institute (HEMORIO) with intravenous bisphosphonate (zoledronic acid), performed dental extractions in a private clinic. Approximately one month later, he complained of pain at the dental extraction site and was referred by the oncologist to the hospital’s dental service. Intraoral clinical examination revealed an extensive area with characteristics of bone necrosis and the panoramic radiography revealed a radiolucent area suggestive of bone sequestration. The combination of clinical and radiographic findings confirmed the diagnosis of bisphosphonate-related osteonecrosis of the jaws (BRONJ). Conclusion: patients under regular continuous use of bisphosphonates must be warned of the possible development of BRONJ after invasive dental procedures and proper guidance must be provided.
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spelling Osteonecrosis of the jaws in a patient with multiple myeloma - a case reportOsteonecrose dos maxilares em paciente com mieloma múltiplo - relato de casoDENTAL MEDICINE (DENTISTRY)Multiple myeloma; Bisphosphonates; Osteonecrosis.MEDICINA DENTÁRIA (ODONTOLOGIA)Mieloma múltiplo; Bisfosfonatos; OsteonecroseObjective: tthis paper reports a case of osteonecrosis of the jaws associated with the use of intravenous bisphosphonates (BRONJ) after extraction of the maxillary right first and second molars. Case report: a 53-year-old male patient with diagnosis of multiple myeloma undergoing treatment at Arthur Siqueira Cavalcanti Institute (HEMORIO) with intravenous bisphosphonate (zoledronic acid), performed dental extractions in a private clinic. Approximately one month later, he complained of pain at the dental extraction site and was referred by the oncologist to the hospital’s dental service. Intraoral clinical examination revealed an extensive area with characteristics of bone necrosis and the panoramic radiography revealed a radiolucent area suggestive of bone sequestration. The combination of clinical and radiographic findings confirmed the diagnosis of bisphosphonate-related osteonecrosis of the jaws (BRONJ). Conclusion: patients under regular continuous use of bisphosphonates must be warned of the possible development of BRONJ after invasive dental procedures and proper guidance must be provided.Objetivo: este artigo relata um caso de osteonecrose dos maxilares associada ao uso de bisfosfonatos intravenosos (BRONJ) após a extração da maxila primeiro e segundo molares direito. Relato de caso: Paciente do sexo masculino, 53 anos, com diagnóstico de mieloma múltiplo em tratamento no Instituto Arthur Siqueira Cavalcanti (HEMORIO), com bisfosfonato endovenoso (ácido zoledrônico), realizou extrações dentárias em clínica privada. Aproximadamente um mês depois, ele se queixou de dor no local da extração dentária e foi encaminhado pelo oncologista para o serviço odontológico do hospital. O exame clínico intraoral revelou extensa área com características de necrose óssea e a radiografia panorâmica revelou área radiolúcida sugestiva de sequestro ósseo. A combinação de achados clínicos e radiográficos confirmou o diagnóstico de osteonecrose dos maxilares relacionada aos bisfosfonatos (BRONJ). Conclusão: os pacientes em uso regular e contínuo de bisfosfonatos devem ser alertados sobre o possível desenvolvimento de BRONJ após procedimentos odontológicos invasivos e devem ser fornecidas orientações adequadas.Associação Brasileira de Odontologia - Seção Rio de JaneiroMendes, Vera Lúcia Duarte da CostaPaoli, Fabiana deHespanhol, Wagner2018-08-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionShort CommunicationComunicação breveapplication/pdfhttps://revista.aborj.org.br/index.php/rbo/article/view/118410.18363/rbo.v75.2018.e1184Revista Brasileira de Odontologia; v. 75 (2018); 1/4Revista Brasileira de Odontologia; v. 75 (2018); 1/41984-3747reponame:Revista Brasileira de Odontologiainstname:Associação Brasileira de Odontologia (ABO)instacron:ABOenghttps://revista.aborj.org.br/index.php/rbo/article/view/1184/708ContemporaryContemporâneaDireitos autorais 2018 Rev. Bras. Odontol.http://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccess2019-08-06T15:46:45Zoai:revista_aborj_org_br.www.revista.aborj.org.br:article/1184Revistahttps://revista.aborj.org.br/index.php/rboONGhttp://www.revista.aborj.org.br/index.php/rbo/oaihttps://revista.aborj.org.br/index.php/rbo/oai0034-72721984-3747opendoar:2019-08-06T15:46:45Revista Brasileira de Odontologia - Associação Brasileira de Odontologia (ABO)false
dc.title.none.fl_str_mv Osteonecrosis of the jaws in a patient with multiple myeloma - a case report
Osteonecrose dos maxilares em paciente com mieloma múltiplo - relato de caso
title Osteonecrosis of the jaws in a patient with multiple myeloma - a case report
spellingShingle Osteonecrosis of the jaws in a patient with multiple myeloma - a case report
Mendes, Vera Lúcia Duarte da Costa
DENTAL MEDICINE (DENTISTRY)
Multiple myeloma; Bisphosphonates; Osteonecrosis.
MEDICINA DENTÁRIA (ODONTOLOGIA)
Mieloma múltiplo; Bisfosfonatos; Osteonecrose
title_short Osteonecrosis of the jaws in a patient with multiple myeloma - a case report
title_full Osteonecrosis of the jaws in a patient with multiple myeloma - a case report
title_fullStr Osteonecrosis of the jaws in a patient with multiple myeloma - a case report
title_full_unstemmed Osteonecrosis of the jaws in a patient with multiple myeloma - a case report
title_sort Osteonecrosis of the jaws in a patient with multiple myeloma - a case report
author Mendes, Vera Lúcia Duarte da Costa
author_facet Mendes, Vera Lúcia Duarte da Costa
Paoli, Fabiana de
Hespanhol, Wagner
author_role author
author2 Paoli, Fabiana de
Hespanhol, Wagner
author2_role author
author
dc.contributor.none.fl_str_mv

dc.contributor.author.fl_str_mv Mendes, Vera Lúcia Duarte da Costa
Paoli, Fabiana de
Hespanhol, Wagner
dc.subject.none.fl_str_mv

dc.subject.por.fl_str_mv DENTAL MEDICINE (DENTISTRY)
Multiple myeloma; Bisphosphonates; Osteonecrosis.
MEDICINA DENTÁRIA (ODONTOLOGIA)
Mieloma múltiplo; Bisfosfonatos; Osteonecrose
topic DENTAL MEDICINE (DENTISTRY)
Multiple myeloma; Bisphosphonates; Osteonecrosis.
MEDICINA DENTÁRIA (ODONTOLOGIA)
Mieloma múltiplo; Bisfosfonatos; Osteonecrose
description Objective: tthis paper reports a case of osteonecrosis of the jaws associated with the use of intravenous bisphosphonates (BRONJ) after extraction of the maxillary right first and second molars. Case report: a 53-year-old male patient with diagnosis of multiple myeloma undergoing treatment at Arthur Siqueira Cavalcanti Institute (HEMORIO) with intravenous bisphosphonate (zoledronic acid), performed dental extractions in a private clinic. Approximately one month later, he complained of pain at the dental extraction site and was referred by the oncologist to the hospital’s dental service. Intraoral clinical examination revealed an extensive area with characteristics of bone necrosis and the panoramic radiography revealed a radiolucent area suggestive of bone sequestration. The combination of clinical and radiographic findings confirmed the diagnosis of bisphosphonate-related osteonecrosis of the jaws (BRONJ). Conclusion: patients under regular continuous use of bisphosphonates must be warned of the possible development of BRONJ after invasive dental procedures and proper guidance must be provided.
publishDate 2018
dc.date.none.fl_str_mv 2018-08-10
dc.type.none.fl_str_mv

dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Short Communication
Comunicação breve
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revista.aborj.org.br/index.php/rbo/article/view/1184
10.18363/rbo.v75.2018.e1184
url https://revista.aborj.org.br/index.php/rbo/article/view/1184
identifier_str_mv 10.18363/rbo.v75.2018.e1184
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://revista.aborj.org.br/index.php/rbo/article/view/1184/708
dc.rights.driver.fl_str_mv Direitos autorais 2018 Rev. Bras. Odontol.
http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos autorais 2018 Rev. Bras. Odontol.
http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.coverage.none.fl_str_mv
Contemporary


Contemporânea
dc.publisher.none.fl_str_mv Associação Brasileira de Odontologia - Seção Rio de Janeiro
publisher.none.fl_str_mv Associação Brasileira de Odontologia - Seção Rio de Janeiro
dc.source.none.fl_str_mv Revista Brasileira de Odontologia; v. 75 (2018); 1/4
Revista Brasileira de Odontologia; v. 75 (2018); 1/4
1984-3747
reponame:Revista Brasileira de Odontologia
instname:Associação Brasileira de Odontologia (ABO)
instacron:ABO
instname_str Associação Brasileira de Odontologia (ABO)
instacron_str ABO
institution ABO
reponame_str Revista Brasileira de Odontologia
collection Revista Brasileira de Odontologia
repository.name.fl_str_mv Revista Brasileira de Odontologia - Associação Brasileira de Odontologia (ABO)
repository.mail.fl_str_mv https://revista.aborj.org.br/index.php/rbo/oai
_version_ 1798313204839874560

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