Current outlook of ethics in research with human subjects

Detalhes bibliográficos
Autor(a) principal: Takahashi,Marystella Tomoe
Data de Publicação: 2011
Outros Autores: Ramos,Henrique Faria, Pinheiro-Neto,Carlos Diógenes, Miziara,Ivan Dieb, Oliveira,Reynaldo Ayer de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Otorhinolaryngology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000200018
Resumo: In the last decades, medical care has been increasingly permeated by the concept of evidence-based-medicine, in which clinical research plays a crucial role in establishing diagnostic and treatment. Following the improvements in clinical research, we have a growing concern and understanding that some ethical issues must be respected when the subjects are human beings. Research with human subjects relies on the principles of autonomy, beneficence, no maleficence and justice. Ordinance 196/96 from the National Health Board adds to the Brazilian legislation such renowned bioethical principles. AIM: Discuss the main ethical aspects involved in research with human subjects. MATERIALS AND METHODS: Critical analysis of Ordinance 196/96 and related literature. CONCLUSION: Ordinance 196/96 rules research with human subjects; nevertheless, it requires more in-depth discussions regarding the informed consent, use of placebo, research with vulnerable populations and research in developing countries.
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spelling Current outlook of ethics in research with human subjectsbioethicsethics committees, researchcodes of ethics, principle-bases ethicsethics, researchIn the last decades, medical care has been increasingly permeated by the concept of evidence-based-medicine, in which clinical research plays a crucial role in establishing diagnostic and treatment. Following the improvements in clinical research, we have a growing concern and understanding that some ethical issues must be respected when the subjects are human beings. Research with human subjects relies on the principles of autonomy, beneficence, no maleficence and justice. Ordinance 196/96 from the National Health Board adds to the Brazilian legislation such renowned bioethical principles. AIM: Discuss the main ethical aspects involved in research with human subjects. MATERIALS AND METHODS: Critical analysis of Ordinance 196/96 and related literature. CONCLUSION: Ordinance 196/96 rules research with human subjects; nevertheless, it requires more in-depth discussions regarding the informed consent, use of placebo, research with vulnerable populations and research in developing countries.Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.2011-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000200018Brazilian Journal of Otorhinolaryngology v.77 n.2 2011reponame:Brazilian Journal of Otorhinolaryngologyinstname:Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)instacron:ABORL-CCF10.1590/S1808-86942011000200018info:eu-repo/semantics/openAccessTakahashi,Marystella TomoeRamos,Henrique FariaPinheiro-Neto,Carlos DiógenesMiziara,Ivan DiebOliveira,Reynaldo Ayer deeng2011-04-25T00:00:00Zoai:scielo:S1808-86942011000200018Revistahttp://www.bjorl.org.br/https://old.scielo.br/oai/scielo-oai.phprevista@aborlccf.org.br||revista@aborlccf.org.br1808-86861808-8686opendoar:2011-04-25T00:00Brazilian Journal of Otorhinolaryngology - Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)false
dc.title.none.fl_str_mv Current outlook of ethics in research with human subjects
title Current outlook of ethics in research with human subjects
spellingShingle Current outlook of ethics in research with human subjects
Takahashi,Marystella Tomoe
bioethics
ethics committees, research
codes of ethics, principle-bases ethics
ethics, research
title_short Current outlook of ethics in research with human subjects
title_full Current outlook of ethics in research with human subjects
title_fullStr Current outlook of ethics in research with human subjects
title_full_unstemmed Current outlook of ethics in research with human subjects
title_sort Current outlook of ethics in research with human subjects
author Takahashi,Marystella Tomoe
author_facet Takahashi,Marystella Tomoe
Ramos,Henrique Faria
Pinheiro-Neto,Carlos Diógenes
Miziara,Ivan Dieb
Oliveira,Reynaldo Ayer de
author_role author
author2 Ramos,Henrique Faria
Pinheiro-Neto,Carlos Diógenes
Miziara,Ivan Dieb
Oliveira,Reynaldo Ayer de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Takahashi,Marystella Tomoe
Ramos,Henrique Faria
Pinheiro-Neto,Carlos Diógenes
Miziara,Ivan Dieb
Oliveira,Reynaldo Ayer de
dc.subject.por.fl_str_mv bioethics
ethics committees, research
codes of ethics, principle-bases ethics
ethics, research
topic bioethics
ethics committees, research
codes of ethics, principle-bases ethics
ethics, research
description In the last decades, medical care has been increasingly permeated by the concept of evidence-based-medicine, in which clinical research plays a crucial role in establishing diagnostic and treatment. Following the improvements in clinical research, we have a growing concern and understanding that some ethical issues must be respected when the subjects are human beings. Research with human subjects relies on the principles of autonomy, beneficence, no maleficence and justice. Ordinance 196/96 from the National Health Board adds to the Brazilian legislation such renowned bioethical principles. AIM: Discuss the main ethical aspects involved in research with human subjects. MATERIALS AND METHODS: Critical analysis of Ordinance 196/96 and related literature. CONCLUSION: Ordinance 196/96 rules research with human subjects; nevertheless, it requires more in-depth discussions regarding the informed consent, use of placebo, research with vulnerable populations and research in developing countries.
publishDate 2011
dc.date.none.fl_str_mv 2011-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000200018
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000200018
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1808-86942011000200018
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.
publisher.none.fl_str_mv Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.
dc.source.none.fl_str_mv Brazilian Journal of Otorhinolaryngology v.77 n.2 2011
reponame:Brazilian Journal of Otorhinolaryngology
instname:Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
instacron:ABORL-CCF
instname_str Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
instacron_str ABORL-CCF
institution ABORL-CCF
reponame_str Brazilian Journal of Otorhinolaryngology
collection Brazilian Journal of Otorhinolaryngology
repository.name.fl_str_mv Brazilian Journal of Otorhinolaryngology - Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
repository.mail.fl_str_mv revista@aborlccf.org.br||revista@aborlccf.org.br
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