Histological analysis of autologous fascia graft implantation into the rabbit voice muscle

Detalhes bibliográficos
Autor(a) principal: Pinna,Bruno de Rezende
Data de Publicação: 2011
Outros Autores: Stavale,João Norberto, Pontes,Paulo Augusto de Lima, Brasil,Osíris de Oliveira Camponês do
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Otorhinolaryngology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000200008
Resumo: The ideal approach for the treatment of glottal insufficiency remains a challenge for laryngologists. AIM: This experimental study assessed the histological changes and fibrosis caused by autologous fascia lata grafts into the rabbit voice muscle. STUDY DESIGN: A clinical and experimental study. METHODS: A 0.2 × 0.2 cm fragment of autologous fascia lata was grafted into the right voice muscle of 14 adult rabbits. Animals were euthanized 30 or 60 days post-procedure and histology of the excised vocal folds was carried out. RESULTS: No extensive edema, necrosis or foreign body-type reaction was observed at any time. No significant inflammatory reaction or fibrosis was seen at 30 or 60 days. CONCLUSION: The presence of fascia lata in the rabbit voice muscle had no significant influence on inflammation, and does not increase fibrosis. Rabbit voice muscle shows good tolerance to fascia lata grafting.
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spelling Histological analysis of autologous fascia graft implantation into the rabbit voice musclelaryngeal diseasesglottisfasciarabbitsvocal cordsThe ideal approach for the treatment of glottal insufficiency remains a challenge for laryngologists. AIM: This experimental study assessed the histological changes and fibrosis caused by autologous fascia lata grafts into the rabbit voice muscle. STUDY DESIGN: A clinical and experimental study. METHODS: A 0.2 × 0.2 cm fragment of autologous fascia lata was grafted into the right voice muscle of 14 adult rabbits. Animals were euthanized 30 or 60 days post-procedure and histology of the excised vocal folds was carried out. RESULTS: No extensive edema, necrosis or foreign body-type reaction was observed at any time. No significant inflammatory reaction or fibrosis was seen at 30 or 60 days. CONCLUSION: The presence of fascia lata in the rabbit voice muscle had no significant influence on inflammation, and does not increase fibrosis. Rabbit voice muscle shows good tolerance to fascia lata grafting.Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.2011-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000200008Brazilian Journal of Otorhinolaryngology v.77 n.2 2011reponame:Brazilian Journal of Otorhinolaryngologyinstname:Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)instacron:ABORL-CCF10.1590/S1808-86942011000200008info:eu-repo/semantics/openAccessPinna,Bruno de RezendeStavale,João NorbertoPontes,Paulo Augusto de LimaBrasil,Osíris de Oliveira Camponês doeng2011-04-25T00:00:00Zoai:scielo:S1808-86942011000200008Revistahttp://www.bjorl.org.br/https://old.scielo.br/oai/scielo-oai.phprevista@aborlccf.org.br||revista@aborlccf.org.br1808-86861808-8686opendoar:2011-04-25T00:00Brazilian Journal of Otorhinolaryngology - Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)false
dc.title.none.fl_str_mv Histological analysis of autologous fascia graft implantation into the rabbit voice muscle
title Histological analysis of autologous fascia graft implantation into the rabbit voice muscle
spellingShingle Histological analysis of autologous fascia graft implantation into the rabbit voice muscle
Pinna,Bruno de Rezende
laryngeal diseases
glottis
fascia
rabbits
vocal cords
title_short Histological analysis of autologous fascia graft implantation into the rabbit voice muscle
title_full Histological analysis of autologous fascia graft implantation into the rabbit voice muscle
title_fullStr Histological analysis of autologous fascia graft implantation into the rabbit voice muscle
title_full_unstemmed Histological analysis of autologous fascia graft implantation into the rabbit voice muscle
title_sort Histological analysis of autologous fascia graft implantation into the rabbit voice muscle
author Pinna,Bruno de Rezende
author_facet Pinna,Bruno de Rezende
Stavale,João Norberto
Pontes,Paulo Augusto de Lima
Brasil,Osíris de Oliveira Camponês do
author_role author
author2 Stavale,João Norberto
Pontes,Paulo Augusto de Lima
Brasil,Osíris de Oliveira Camponês do
author2_role author
author
author
dc.contributor.author.fl_str_mv Pinna,Bruno de Rezende
Stavale,João Norberto
Pontes,Paulo Augusto de Lima
Brasil,Osíris de Oliveira Camponês do
dc.subject.por.fl_str_mv laryngeal diseases
glottis
fascia
rabbits
vocal cords
topic laryngeal diseases
glottis
fascia
rabbits
vocal cords
description The ideal approach for the treatment of glottal insufficiency remains a challenge for laryngologists. AIM: This experimental study assessed the histological changes and fibrosis caused by autologous fascia lata grafts into the rabbit voice muscle. STUDY DESIGN: A clinical and experimental study. METHODS: A 0.2 × 0.2 cm fragment of autologous fascia lata was grafted into the right voice muscle of 14 adult rabbits. Animals were euthanized 30 or 60 days post-procedure and histology of the excised vocal folds was carried out. RESULTS: No extensive edema, necrosis or foreign body-type reaction was observed at any time. No significant inflammatory reaction or fibrosis was seen at 30 or 60 days. CONCLUSION: The presence of fascia lata in the rabbit voice muscle had no significant influence on inflammation, and does not increase fibrosis. Rabbit voice muscle shows good tolerance to fascia lata grafting.
publishDate 2011
dc.date.none.fl_str_mv 2011-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000200008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000200008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1808-86942011000200008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.
publisher.none.fl_str_mv Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.
dc.source.none.fl_str_mv Brazilian Journal of Otorhinolaryngology v.77 n.2 2011
reponame:Brazilian Journal of Otorhinolaryngology
instname:Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
instacron:ABORL-CCF
instname_str Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
instacron_str ABORL-CCF
institution ABORL-CCF
reponame_str Brazilian Journal of Otorhinolaryngology
collection Brazilian Journal of Otorhinolaryngology
repository.name.fl_str_mv Brazilian Journal of Otorhinolaryngology - Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
repository.mail.fl_str_mv revista@aborlccf.org.br||revista@aborlccf.org.br
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