Histological analysis of autologous fascia graft implantation into the rabbit voice muscle
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Otorhinolaryngology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000200008 |
Resumo: | The ideal approach for the treatment of glottal insufficiency remains a challenge for laryngologists. AIM: This experimental study assessed the histological changes and fibrosis caused by autologous fascia lata grafts into the rabbit voice muscle. STUDY DESIGN: A clinical and experimental study. METHODS: A 0.2 × 0.2 cm fragment of autologous fascia lata was grafted into the right voice muscle of 14 adult rabbits. Animals were euthanized 30 or 60 days post-procedure and histology of the excised vocal folds was carried out. RESULTS: No extensive edema, necrosis or foreign body-type reaction was observed at any time. No significant inflammatory reaction or fibrosis was seen at 30 or 60 days. CONCLUSION: The presence of fascia lata in the rabbit voice muscle had no significant influence on inflammation, and does not increase fibrosis. Rabbit voice muscle shows good tolerance to fascia lata grafting. |
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Brazilian Journal of Otorhinolaryngology |
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spelling |
Histological analysis of autologous fascia graft implantation into the rabbit voice musclelaryngeal diseasesglottisfasciarabbitsvocal cordsThe ideal approach for the treatment of glottal insufficiency remains a challenge for laryngologists. AIM: This experimental study assessed the histological changes and fibrosis caused by autologous fascia lata grafts into the rabbit voice muscle. STUDY DESIGN: A clinical and experimental study. METHODS: A 0.2 × 0.2 cm fragment of autologous fascia lata was grafted into the right voice muscle of 14 adult rabbits. Animals were euthanized 30 or 60 days post-procedure and histology of the excised vocal folds was carried out. RESULTS: No extensive edema, necrosis or foreign body-type reaction was observed at any time. No significant inflammatory reaction or fibrosis was seen at 30 or 60 days. CONCLUSION: The presence of fascia lata in the rabbit voice muscle had no significant influence on inflammation, and does not increase fibrosis. Rabbit voice muscle shows good tolerance to fascia lata grafting.Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.2011-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000200008Brazilian Journal of Otorhinolaryngology v.77 n.2 2011reponame:Brazilian Journal of Otorhinolaryngologyinstname:Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)instacron:ABORL-CCF10.1590/S1808-86942011000200008info:eu-repo/semantics/openAccessPinna,Bruno de RezendeStavale,João NorbertoPontes,Paulo Augusto de LimaBrasil,Osíris de Oliveira Camponês doeng2011-04-25T00:00:00Zoai:scielo:S1808-86942011000200008Revistahttp://www.bjorl.org.br/https://old.scielo.br/oai/scielo-oai.phprevista@aborlccf.org.br||revista@aborlccf.org.br1808-86861808-8686opendoar:2011-04-25T00:00Brazilian Journal of Otorhinolaryngology - Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)false |
dc.title.none.fl_str_mv |
Histological analysis of autologous fascia graft implantation into the rabbit voice muscle |
title |
Histological analysis of autologous fascia graft implantation into the rabbit voice muscle |
spellingShingle |
Histological analysis of autologous fascia graft implantation into the rabbit voice muscle Pinna,Bruno de Rezende laryngeal diseases glottis fascia rabbits vocal cords |
title_short |
Histological analysis of autologous fascia graft implantation into the rabbit voice muscle |
title_full |
Histological analysis of autologous fascia graft implantation into the rabbit voice muscle |
title_fullStr |
Histological analysis of autologous fascia graft implantation into the rabbit voice muscle |
title_full_unstemmed |
Histological analysis of autologous fascia graft implantation into the rabbit voice muscle |
title_sort |
Histological analysis of autologous fascia graft implantation into the rabbit voice muscle |
author |
Pinna,Bruno de Rezende |
author_facet |
Pinna,Bruno de Rezende Stavale,João Norberto Pontes,Paulo Augusto de Lima Brasil,Osíris de Oliveira Camponês do |
author_role |
author |
author2 |
Stavale,João Norberto Pontes,Paulo Augusto de Lima Brasil,Osíris de Oliveira Camponês do |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Pinna,Bruno de Rezende Stavale,João Norberto Pontes,Paulo Augusto de Lima Brasil,Osíris de Oliveira Camponês do |
dc.subject.por.fl_str_mv |
laryngeal diseases glottis fascia rabbits vocal cords |
topic |
laryngeal diseases glottis fascia rabbits vocal cords |
description |
The ideal approach for the treatment of glottal insufficiency remains a challenge for laryngologists. AIM: This experimental study assessed the histological changes and fibrosis caused by autologous fascia lata grafts into the rabbit voice muscle. STUDY DESIGN: A clinical and experimental study. METHODS: A 0.2 × 0.2 cm fragment of autologous fascia lata was grafted into the right voice muscle of 14 adult rabbits. Animals were euthanized 30 or 60 days post-procedure and histology of the excised vocal folds was carried out. RESULTS: No extensive edema, necrosis or foreign body-type reaction was observed at any time. No significant inflammatory reaction or fibrosis was seen at 30 or 60 days. CONCLUSION: The presence of fascia lata in the rabbit voice muscle had no significant influence on inflammation, and does not increase fibrosis. Rabbit voice muscle shows good tolerance to fascia lata grafting. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000200008 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000200008 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1808-86942011000200008 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. |
publisher.none.fl_str_mv |
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. |
dc.source.none.fl_str_mv |
Brazilian Journal of Otorhinolaryngology v.77 n.2 2011 reponame:Brazilian Journal of Otorhinolaryngology instname:Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF) instacron:ABORL-CCF |
instname_str |
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF) |
instacron_str |
ABORL-CCF |
institution |
ABORL-CCF |
reponame_str |
Brazilian Journal of Otorhinolaryngology |
collection |
Brazilian Journal of Otorhinolaryngology |
repository.name.fl_str_mv |
Brazilian Journal of Otorhinolaryngology - Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF) |
repository.mail.fl_str_mv |
revista@aborlccf.org.br||revista@aborlccf.org.br |
_version_ |
1754575989422161920 |