Neural complications and physical disabilities in leprosy in a capital of northeastern Brazil with high endemicity
Autor(a) principal: | |
---|---|
Data de Publicação: | 2014 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista brasileira de epidemiologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2014000400899 |
Resumo: | INTRODUCTION: Leprosy is an infectious disease whose etiologic agent is Mycobacterium leprae, manifested by dermatological and neurological signs and symptoms. OBJECTIVE: To investigate neural changes and the degree of physical disability in the eyes, hands and feet before and after treatment, as well as sociodemographic and clinical profile of patients affected by leprosy. METHOD: A longitudinal epidemiological study comprising 155 patients with leprosy, from a spontaneous demand, diagnosed between March 2010 and February 2011, and treated with multidrug therapy (MDT) between March 2010 and July 2012 in a program for leprosy eradication in São Luis (MA), Brazil. RESULTS: Before treatment, 46.5% of patients were considered as borderline, 51.6% had some alteration in the eyes and 52.3% in the feet, and the radial nerve (18.7%) was the most affected. There was a statistically significant difference between the changes in the radial nerve at the beginning of and after treatment. CONCLUSIONS: The analysis points to late diagnosis, as some patients have had abnormal neural and physical disabilities before treatment. |
id |
ABRASCO-1_0d182327506bca0f907c365335496067 |
---|---|
oai_identifier_str |
oai:scielo:S1415-790X2014000400899 |
network_acronym_str |
ABRASCO-1 |
network_name_str |
Revista brasileira de epidemiologia (Online) |
repository_id_str |
|
spelling |
Neural complications and physical disabilities in leprosy in a capital of northeastern Brazil with high endemicityLeprosyTherapeuticsDisabled personsMycobacterium lepraeNerve degenerationEpidemiology INTRODUCTION: Leprosy is an infectious disease whose etiologic agent is Mycobacterium leprae, manifested by dermatological and neurological signs and symptoms. OBJECTIVE: To investigate neural changes and the degree of physical disability in the eyes, hands and feet before and after treatment, as well as sociodemographic and clinical profile of patients affected by leprosy. METHOD: A longitudinal epidemiological study comprising 155 patients with leprosy, from a spontaneous demand, diagnosed between March 2010 and February 2011, and treated with multidrug therapy (MDT) between March 2010 and July 2012 in a program for leprosy eradication in São Luis (MA), Brazil. RESULTS: Before treatment, 46.5% of patients were considered as borderline, 51.6% had some alteration in the eyes and 52.3% in the feet, and the radial nerve (18.7%) was the most affected. There was a statistically significant difference between the changes in the radial nerve at the beginning of and after treatment. CONCLUSIONS: The analysis points to late diagnosis, as some patients have had abnormal neural and physical disabilities before treatment. Associação Brasileira de Saúde Coletiva2014-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2014000400899Revista Brasileira de Epidemiologia v.17 n.4 2014reponame:Revista brasileira de epidemiologia (Online)instname:Associação Brasileira de Saúde Coletiva (ABRASCO)instacron:ABRASCO10.1590/1809-4503201400040009info:eu-repo/semantics/openAccessAraújo,Ana Eugênia Ribeiro de Araújo eAquino,Dorlene Maria Cardoso deGoulart,Isabela Maria BernardesPereira,Silma Regina FerreiraFigueiredo,Ivan AbreuSerra,Humberto OliveiraFonseca,Poliana Cristina de AlmeidaCaldas,Arlene de Jesus Mendeseng2014-11-04T00:00:00Zoai:scielo:S1415-790X2014000400899Revistahttp://www.scielo.br/rbepidhttps://old.scielo.br/oai/scielo-oai.php||revbrepi@usp.br1980-54971415-790Xopendoar:2014-11-04T00:00Revista brasileira de epidemiologia (Online) - Associação Brasileira de Saúde Coletiva (ABRASCO)false |
dc.title.none.fl_str_mv |
Neural complications and physical disabilities in leprosy in a capital of northeastern Brazil with high endemicity |
title |
Neural complications and physical disabilities in leprosy in a capital of northeastern Brazil with high endemicity |
spellingShingle |
Neural complications and physical disabilities in leprosy in a capital of northeastern Brazil with high endemicity Araújo,Ana Eugênia Ribeiro de Araújo e Leprosy Therapeutics Disabled persons Mycobacterium leprae Nerve degeneration Epidemiology |
title_short |
Neural complications and physical disabilities in leprosy in a capital of northeastern Brazil with high endemicity |
title_full |
Neural complications and physical disabilities in leprosy in a capital of northeastern Brazil with high endemicity |
title_fullStr |
Neural complications and physical disabilities in leprosy in a capital of northeastern Brazil with high endemicity |
title_full_unstemmed |
Neural complications and physical disabilities in leprosy in a capital of northeastern Brazil with high endemicity |
title_sort |
Neural complications and physical disabilities in leprosy in a capital of northeastern Brazil with high endemicity |
author |
Araújo,Ana Eugênia Ribeiro de Araújo e |
author_facet |
Araújo,Ana Eugênia Ribeiro de Araújo e Aquino,Dorlene Maria Cardoso de Goulart,Isabela Maria Bernardes Pereira,Silma Regina Ferreira Figueiredo,Ivan Abreu Serra,Humberto Oliveira Fonseca,Poliana Cristina de Almeida Caldas,Arlene de Jesus Mendes |
author_role |
author |
author2 |
Aquino,Dorlene Maria Cardoso de Goulart,Isabela Maria Bernardes Pereira,Silma Regina Ferreira Figueiredo,Ivan Abreu Serra,Humberto Oliveira Fonseca,Poliana Cristina de Almeida Caldas,Arlene de Jesus Mendes |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Araújo,Ana Eugênia Ribeiro de Araújo e Aquino,Dorlene Maria Cardoso de Goulart,Isabela Maria Bernardes Pereira,Silma Regina Ferreira Figueiredo,Ivan Abreu Serra,Humberto Oliveira Fonseca,Poliana Cristina de Almeida Caldas,Arlene de Jesus Mendes |
dc.subject.por.fl_str_mv |
Leprosy Therapeutics Disabled persons Mycobacterium leprae Nerve degeneration Epidemiology |
topic |
Leprosy Therapeutics Disabled persons Mycobacterium leprae Nerve degeneration Epidemiology |
description |
INTRODUCTION: Leprosy is an infectious disease whose etiologic agent is Mycobacterium leprae, manifested by dermatological and neurological signs and symptoms. OBJECTIVE: To investigate neural changes and the degree of physical disability in the eyes, hands and feet before and after treatment, as well as sociodemographic and clinical profile of patients affected by leprosy. METHOD: A longitudinal epidemiological study comprising 155 patients with leprosy, from a spontaneous demand, diagnosed between March 2010 and February 2011, and treated with multidrug therapy (MDT) between March 2010 and July 2012 in a program for leprosy eradication in São Luis (MA), Brazil. RESULTS: Before treatment, 46.5% of patients were considered as borderline, 51.6% had some alteration in the eyes and 52.3% in the feet, and the radial nerve (18.7%) was the most affected. There was a statistically significant difference between the changes in the radial nerve at the beginning of and after treatment. CONCLUSIONS: The analysis points to late diagnosis, as some patients have had abnormal neural and physical disabilities before treatment. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2014000400899 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2014000400899 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1809-4503201400040009 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Saúde Coletiva |
publisher.none.fl_str_mv |
Associação Brasileira de Saúde Coletiva |
dc.source.none.fl_str_mv |
Revista Brasileira de Epidemiologia v.17 n.4 2014 reponame:Revista brasileira de epidemiologia (Online) instname:Associação Brasileira de Saúde Coletiva (ABRASCO) instacron:ABRASCO |
instname_str |
Associação Brasileira de Saúde Coletiva (ABRASCO) |
instacron_str |
ABRASCO |
institution |
ABRASCO |
reponame_str |
Revista brasileira de epidemiologia (Online) |
collection |
Revista brasileira de epidemiologia (Online) |
repository.name.fl_str_mv |
Revista brasileira de epidemiologia (Online) - Associação Brasileira de Saúde Coletiva (ABRASCO) |
repository.mail.fl_str_mv |
||revbrepi@usp.br |
_version_ |
1754212953863749632 |