Human papillomavirus (HPV) detection in lip squamous cell carcinoma: correlation with clinical aspects and risk factors

Detalhes bibliográficos
Autor(a) principal: Demathe,Adriana
Data de Publicação: 2011
Outros Autores: Garcia,José Fernando, Mattar,Neivio José, Simonato,Luciana Estevam, Miyahara,Glauco Issamu
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista brasileira de epidemiologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2011000100009
Resumo: Human papillomavirus (HPV) is associated with a wide spectrum of lesions in humans, and it has been linked to oral carcinogenesis. The aim of this study was to investigate the presence of HPV DNA in patients with lip squamous cell carcinoma and to correlate it with clinical characteristics and risk factors. We studied 33 patients with lip squamous cell carcinomas. Of these, 30 were positive for human beta globin gene and tested for HPV DNA, using polymerase chain reaction in two steps (PCR and nPCR) with MY11/MY09 and GP5+/GP6+ primers. HPV DNA was detected in 43.33% of patients analyzed. There was no association with the risk factors analyzed.
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spelling Human papillomavirus (HPV) detection in lip squamous cell carcinoma: correlation with clinical aspects and risk factorsEpidemiologyLaboratory researchSquamous cell carcinomaPapillomaviridaePolimerase chain reactionOligonucleotidesHuman papillomavirus (HPV) is associated with a wide spectrum of lesions in humans, and it has been linked to oral carcinogenesis. The aim of this study was to investigate the presence of HPV DNA in patients with lip squamous cell carcinoma and to correlate it with clinical characteristics and risk factors. We studied 33 patients with lip squamous cell carcinomas. Of these, 30 were positive for human beta globin gene and tested for HPV DNA, using polymerase chain reaction in two steps (PCR and nPCR) with MY11/MY09 and GP5+/GP6+ primers. HPV DNA was detected in 43.33% of patients analyzed. There was no association with the risk factors analyzed.Associação Brasileira de Saúde Coletiva2011-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2011000100009Revista Brasileira de Epidemiologia v.14 n.1 2011reponame:Revista brasileira de epidemiologia (Online)instname:Associação Brasileira de Saúde Coletiva (ABRASCO)instacron:ABRASCO10.1590/S1415-790X2011000100009info:eu-repo/semantics/openAccessDemathe,AdrianaGarcia,José FernandoMattar,Neivio JoséSimonato,Luciana EstevamMiyahara,Glauco Issamueng2011-03-03T00:00:00Zoai:scielo:S1415-790X2011000100009Revistahttp://www.scielo.br/rbepidhttps://old.scielo.br/oai/scielo-oai.php||revbrepi@usp.br1980-54971415-790Xopendoar:2011-03-03T00:00Revista brasileira de epidemiologia (Online) - Associação Brasileira de Saúde Coletiva (ABRASCO)false
dc.title.none.fl_str_mv Human papillomavirus (HPV) detection in lip squamous cell carcinoma: correlation with clinical aspects and risk factors
title Human papillomavirus (HPV) detection in lip squamous cell carcinoma: correlation with clinical aspects and risk factors
spellingShingle Human papillomavirus (HPV) detection in lip squamous cell carcinoma: correlation with clinical aspects and risk factors
Demathe,Adriana
Epidemiology
Laboratory research
Squamous cell carcinoma
Papillomaviridae
Polimerase chain reaction
Oligonucleotides
title_short Human papillomavirus (HPV) detection in lip squamous cell carcinoma: correlation with clinical aspects and risk factors
title_full Human papillomavirus (HPV) detection in lip squamous cell carcinoma: correlation with clinical aspects and risk factors
title_fullStr Human papillomavirus (HPV) detection in lip squamous cell carcinoma: correlation with clinical aspects and risk factors
title_full_unstemmed Human papillomavirus (HPV) detection in lip squamous cell carcinoma: correlation with clinical aspects and risk factors
title_sort Human papillomavirus (HPV) detection in lip squamous cell carcinoma: correlation with clinical aspects and risk factors
author Demathe,Adriana
author_facet Demathe,Adriana
Garcia,José Fernando
Mattar,Neivio José
Simonato,Luciana Estevam
Miyahara,Glauco Issamu
author_role author
author2 Garcia,José Fernando
Mattar,Neivio José
Simonato,Luciana Estevam
Miyahara,Glauco Issamu
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Demathe,Adriana
Garcia,José Fernando
Mattar,Neivio José
Simonato,Luciana Estevam
Miyahara,Glauco Issamu
dc.subject.por.fl_str_mv Epidemiology
Laboratory research
Squamous cell carcinoma
Papillomaviridae
Polimerase chain reaction
Oligonucleotides
topic Epidemiology
Laboratory research
Squamous cell carcinoma
Papillomaviridae
Polimerase chain reaction
Oligonucleotides
description Human papillomavirus (HPV) is associated with a wide spectrum of lesions in humans, and it has been linked to oral carcinogenesis. The aim of this study was to investigate the presence of HPV DNA in patients with lip squamous cell carcinoma and to correlate it with clinical characteristics and risk factors. We studied 33 patients with lip squamous cell carcinomas. Of these, 30 were positive for human beta globin gene and tested for HPV DNA, using polymerase chain reaction in two steps (PCR and nPCR) with MY11/MY09 and GP5+/GP6+ primers. HPV DNA was detected in 43.33% of patients analyzed. There was no association with the risk factors analyzed.
publishDate 2011
dc.date.none.fl_str_mv 2011-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2011000100009
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2011000100009
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1415-790X2011000100009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Saúde Coletiva
publisher.none.fl_str_mv Associação Brasileira de Saúde Coletiva
dc.source.none.fl_str_mv Revista Brasileira de Epidemiologia v.14 n.1 2011
reponame:Revista brasileira de epidemiologia (Online)
instname:Associação Brasileira de Saúde Coletiva (ABRASCO)
instacron:ABRASCO
instname_str Associação Brasileira de Saúde Coletiva (ABRASCO)
instacron_str ABRASCO
institution ABRASCO
reponame_str Revista brasileira de epidemiologia (Online)
collection Revista brasileira de epidemiologia (Online)
repository.name.fl_str_mv Revista brasileira de epidemiologia (Online) - Associação Brasileira de Saúde Coletiva (ABRASCO)
repository.mail.fl_str_mv ||revbrepi@usp.br
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