Human rabies post-exposure prophylaxis relative to the disease epidemiological status
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Ciência & Saúde Coletiva (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-81232019000100315 |
Resumo: | Abstract This study evaluated the prophylactic measures adopted after attacks by dogs and cats in the main city of Northwester São Paulo State, based on the technical manual for post-exposure treatment, considering the not controlled (1990-1996) and controlled (1997-2010) rabies status. A retrospective analysis was done using the data from the SINAN records (W64-CID10) between 1990 and 2010. In most cases, the accidents were mild (76.9%), and biting animals were healthy (75.4%); therefore, no treatment was needed in 53.3% of the cases. In 64.6% of cases, the prescribed PEP treatment was inappropriate. The most indicated PEP treatments consisted of vaccine and RIG (43.4%), and either three doses of mouse brain vaccine or two doses of cell culture vaccine (76.5%), during the not controlled and controlled rabies periods, respectively. The treatment was more appropriate and followed the technical recommendations during controlled rabies periods compared to not controlled (p < 0.0001) periods. However, excessive application of RIG and rabies vaccine was observed in both periods. |
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Human rabies post-exposure prophylaxis relative to the disease epidemiological statusRabiesAnimal aggressionPost-exposure prophylaxisImmunization scheduleDogsAbstract This study evaluated the prophylactic measures adopted after attacks by dogs and cats in the main city of Northwester São Paulo State, based on the technical manual for post-exposure treatment, considering the not controlled (1990-1996) and controlled (1997-2010) rabies status. A retrospective analysis was done using the data from the SINAN records (W64-CID10) between 1990 and 2010. In most cases, the accidents were mild (76.9%), and biting animals were healthy (75.4%); therefore, no treatment was needed in 53.3% of the cases. In 64.6% of cases, the prescribed PEP treatment was inappropriate. The most indicated PEP treatments consisted of vaccine and RIG (43.4%), and either three doses of mouse brain vaccine or two doses of cell culture vaccine (76.5%), during the not controlled and controlled rabies periods, respectively. The treatment was more appropriate and followed the technical recommendations during controlled rabies periods compared to not controlled (p < 0.0001) periods. However, excessive application of RIG and rabies vaccine was observed in both periods.ABRASCO - Associação Brasileira de Saúde Coletiva2019-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-81232019000100315Ciência & Saúde Coletiva v.24 n.1 2019reponame:Ciência & Saúde Coletiva (Online)instname:Associação Brasileira de Saúde Coletiva (ABRASCO)instacron:ABRASCO10.1590/1413-81232018241.32832016info:eu-repo/semantics/openAccessAndrade,Bruno Fonseca Martins da CostaAndrade,Taísa Santos de MeloQueiroz,Luzia Helenaeng2019-04-05T00:00:00Zoai:scielo:S1413-81232019000100315Revistahttp://www.cienciaesaudecoletiva.com.brhttps://old.scielo.br/oai/scielo-oai.php||cienciasaudecoletiva@fiocruz.br1678-45611413-8123opendoar:2019-04-05T00:00Ciência & Saúde Coletiva (Online) - Associação Brasileira de Saúde Coletiva (ABRASCO)false |
dc.title.none.fl_str_mv |
Human rabies post-exposure prophylaxis relative to the disease epidemiological status |
title |
Human rabies post-exposure prophylaxis relative to the disease epidemiological status |
spellingShingle |
Human rabies post-exposure prophylaxis relative to the disease epidemiological status Andrade,Bruno Fonseca Martins da Costa Rabies Animal aggression Post-exposure prophylaxis Immunization schedule Dogs |
title_short |
Human rabies post-exposure prophylaxis relative to the disease epidemiological status |
title_full |
Human rabies post-exposure prophylaxis relative to the disease epidemiological status |
title_fullStr |
Human rabies post-exposure prophylaxis relative to the disease epidemiological status |
title_full_unstemmed |
Human rabies post-exposure prophylaxis relative to the disease epidemiological status |
title_sort |
Human rabies post-exposure prophylaxis relative to the disease epidemiological status |
author |
Andrade,Bruno Fonseca Martins da Costa |
author_facet |
Andrade,Bruno Fonseca Martins da Costa Andrade,Taísa Santos de Melo Queiroz,Luzia Helena |
author_role |
author |
author2 |
Andrade,Taísa Santos de Melo Queiroz,Luzia Helena |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Andrade,Bruno Fonseca Martins da Costa Andrade,Taísa Santos de Melo Queiroz,Luzia Helena |
dc.subject.por.fl_str_mv |
Rabies Animal aggression Post-exposure prophylaxis Immunization schedule Dogs |
topic |
Rabies Animal aggression Post-exposure prophylaxis Immunization schedule Dogs |
description |
Abstract This study evaluated the prophylactic measures adopted after attacks by dogs and cats in the main city of Northwester São Paulo State, based on the technical manual for post-exposure treatment, considering the not controlled (1990-1996) and controlled (1997-2010) rabies status. A retrospective analysis was done using the data from the SINAN records (W64-CID10) between 1990 and 2010. In most cases, the accidents were mild (76.9%), and biting animals were healthy (75.4%); therefore, no treatment was needed in 53.3% of the cases. In 64.6% of cases, the prescribed PEP treatment was inappropriate. The most indicated PEP treatments consisted of vaccine and RIG (43.4%), and either three doses of mouse brain vaccine or two doses of cell culture vaccine (76.5%), during the not controlled and controlled rabies periods, respectively. The treatment was more appropriate and followed the technical recommendations during controlled rabies periods compared to not controlled (p < 0.0001) periods. However, excessive application of RIG and rabies vaccine was observed in both periods. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-81232019000100315 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-81232019000100315 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1413-81232018241.32832016 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
ABRASCO - Associação Brasileira de Saúde Coletiva |
publisher.none.fl_str_mv |
ABRASCO - Associação Brasileira de Saúde Coletiva |
dc.source.none.fl_str_mv |
Ciência & Saúde Coletiva v.24 n.1 2019 reponame:Ciência & Saúde Coletiva (Online) instname:Associação Brasileira de Saúde Coletiva (ABRASCO) instacron:ABRASCO |
instname_str |
Associação Brasileira de Saúde Coletiva (ABRASCO) |
instacron_str |
ABRASCO |
institution |
ABRASCO |
reponame_str |
Ciência & Saúde Coletiva (Online) |
collection |
Ciência & Saúde Coletiva (Online) |
repository.name.fl_str_mv |
Ciência & Saúde Coletiva (Online) - Associação Brasileira de Saúde Coletiva (ABRASCO) |
repository.mail.fl_str_mv |
||cienciasaudecoletiva@fiocruz.br |
_version_ |
1754213043076595712 |