Relevance of prognostic factors in the decision-making of stem cell transplantation in Myelodysplastic Syndromes

• Autor(a) principal: Duarte,Fernando Barroso
• Data de Publicação: 2016
• Outros Autores: Santos,Talyta Ellen de Jesus dos, Barbosa,Maritza Cavalcante, Kaufman,Jacques, Vasconcelos,João Paulo de, Lemes,Romélia Pinheiro Gonçalves, Rocha,Francisco Dário, Coutinho,Diego Ferreira, Zalcberg,Ilana, Vasconcelos,Paulo Roberto Leitão de
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista da Associação Médica Brasileira (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016001200025
• topic: Myelodysplastic Syndrome; Hematopoietic Stem Cell Transplantation; Prognosis

ABSTRACT The hematopoietic stem cell transplantation (HSCT) is the only curative alternative for Myelodysplastic Syndrome (MDS), but many patients are not eligible for this treatment, as there are several limiting factors, especially in the case of patients with low-risk MDS. The aim of this study is to discuss the factors that can guide the decision-making on referring or not a patient to HSCT. Three cases of MDS, two of which were submitted to HSCT are presented. We intend to report the difficulties in referring patients with MDS to transplant and the prognostic factors that contribute to define eligibility.