Myelodysplastic syndromes (MDS): prognostic factors and scoring systems

Detalhes bibliográficos
Autor(a) principal: Souto,Elizabeth Xisto
Data de Publicação: 1997
Outros Autores: Chauffaile,Maria de Lourdes Lopes Ferrari, Moncau,José Eduardo Cajado, Niero-Melo,Lígia, Braga,Gisele Wally, Silva,Maria Regina Regis, Kerbauy,José
Tipo de documento: Artigo
Idioma: eng
Título da fonte: São Paulo medical journal (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801997000500005
Resumo: OBJECTIVE: To evaluate the score systems of Cassano and Sanz and suggest a new one. DESIGN: Case series. LOCATION: Teaching hospitals: EPM UNIFESP and Faculdade de Medicina de Botucatu. PARTICIPANTS: 59 patients diagnosed from 1979 to 1992. INTERVENTION: Evaluation of clinical-laboratorial data. MEASUREMENT: Statistical comparison, uni and multivariate analysis and actuarial survival curves. RESULTS: Cassano's system divided the patients into high and low risk (p=0.0966) while, Sanz's gave high, intermediate and low risk (p=0.0108). The univariate analysis showed hemoglobin, WBC count, E/M ratio, liver size and blast percentage in BM as statistically significant. The multivariate analysis showed blast percentage in BM (p=0.004) and Hb (p=0.050) as significant. Our system, considering the multivariate analysis data, divided the patients into high, intermediate and low risk (p=0.0038). CONCLUSIONS: Sanz's system was more functional than Cassano's, while ours showed predictive survival value and ease of use in clinical practice.
id APM-1_68889d549ec07f994312527aeebcad5d
oai_identifier_str oai:scielo:S1516-31801997000500005
network_acronym_str APM-1
network_name_str São Paulo medical journal (Online)
repository_id_str
spelling Myelodysplastic syndromes (MDS): prognostic factors and scoring systemsMyelodysplastic syndromesPrognosisSurvivalOBJECTIVE: To evaluate the score systems of Cassano and Sanz and suggest a new one. DESIGN: Case series. LOCATION: Teaching hospitals: EPM UNIFESP and Faculdade de Medicina de Botucatu. PARTICIPANTS: 59 patients diagnosed from 1979 to 1992. INTERVENTION: Evaluation of clinical-laboratorial data. MEASUREMENT: Statistical comparison, uni and multivariate analysis and actuarial survival curves. RESULTS: Cassano's system divided the patients into high and low risk (p=0.0966) while, Sanz's gave high, intermediate and low risk (p=0.0108). The univariate analysis showed hemoglobin, WBC count, E/M ratio, liver size and blast percentage in BM as statistically significant. The multivariate analysis showed blast percentage in BM (p=0.004) and Hb (p=0.050) as significant. Our system, considering the multivariate analysis data, divided the patients into high, intermediate and low risk (p=0.0038). CONCLUSIONS: Sanz's system was more functional than Cassano's, while ours showed predictive survival value and ease of use in clinical practice.Associação Paulista de Medicina - APM1997-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801997000500005Sao Paulo Medical Journal v.115 n.5 1997reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APM10.1590/S1516-31801997000500005info:eu-repo/semantics/openAccessSouto,Elizabeth XistoChauffaile,Maria de Lourdes Lopes FerrariMoncau,José Eduardo CajadoNiero-Melo,LígiaBraga,Gisele WallySilva,Maria Regina RegisKerbauy,Joséeng2008-10-16T00:00:00Zoai:scielo:S1516-31801997000500005Revistahttp://www.scielo.br/spmjhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2008-10-16T00:00São Paulo medical journal (Online) - Associação Paulista de Medicinafalse
dc.title.none.fl_str_mv Myelodysplastic syndromes (MDS): prognostic factors and scoring systems
title Myelodysplastic syndromes (MDS): prognostic factors and scoring systems
spellingShingle Myelodysplastic syndromes (MDS): prognostic factors and scoring systems
Souto,Elizabeth Xisto
Myelodysplastic syndromes
Prognosis
Survival
title_short Myelodysplastic syndromes (MDS): prognostic factors and scoring systems
title_full Myelodysplastic syndromes (MDS): prognostic factors and scoring systems
title_fullStr Myelodysplastic syndromes (MDS): prognostic factors and scoring systems
title_full_unstemmed Myelodysplastic syndromes (MDS): prognostic factors and scoring systems
title_sort Myelodysplastic syndromes (MDS): prognostic factors and scoring systems
author Souto,Elizabeth Xisto
author_facet Souto,Elizabeth Xisto
Chauffaile,Maria de Lourdes Lopes Ferrari
Moncau,José Eduardo Cajado
Niero-Melo,Lígia
Braga,Gisele Wally
Silva,Maria Regina Regis
Kerbauy,José
author_role author
author2 Chauffaile,Maria de Lourdes Lopes Ferrari
Moncau,José Eduardo Cajado
Niero-Melo,Lígia
Braga,Gisele Wally
Silva,Maria Regina Regis
Kerbauy,José
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Souto,Elizabeth Xisto
Chauffaile,Maria de Lourdes Lopes Ferrari
Moncau,José Eduardo Cajado
Niero-Melo,Lígia
Braga,Gisele Wally
Silva,Maria Regina Regis
Kerbauy,José
dc.subject.por.fl_str_mv Myelodysplastic syndromes
Prognosis
Survival
topic Myelodysplastic syndromes
Prognosis
Survival
description OBJECTIVE: To evaluate the score systems of Cassano and Sanz and suggest a new one. DESIGN: Case series. LOCATION: Teaching hospitals: EPM UNIFESP and Faculdade de Medicina de Botucatu. PARTICIPANTS: 59 patients diagnosed from 1979 to 1992. INTERVENTION: Evaluation of clinical-laboratorial data. MEASUREMENT: Statistical comparison, uni and multivariate analysis and actuarial survival curves. RESULTS: Cassano's system divided the patients into high and low risk (p=0.0966) while, Sanz's gave high, intermediate and low risk (p=0.0108). The univariate analysis showed hemoglobin, WBC count, E/M ratio, liver size and blast percentage in BM as statistically significant. The multivariate analysis showed blast percentage in BM (p=0.004) and Hb (p=0.050) as significant. Our system, considering the multivariate analysis data, divided the patients into high, intermediate and low risk (p=0.0038). CONCLUSIONS: Sanz's system was more functional than Cassano's, while ours showed predictive survival value and ease of use in clinical practice.
publishDate 1997
dc.date.none.fl_str_mv 1997-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801997000500005
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801997000500005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-31801997000500005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Paulista de Medicina - APM
publisher.none.fl_str_mv Associação Paulista de Medicina - APM
dc.source.none.fl_str_mv Sao Paulo Medical Journal v.115 n.5 1997
reponame:São Paulo medical journal (Online)
instname:Associação Paulista de Medicina
instacron:APM
instname_str Associação Paulista de Medicina
instacron_str APM
institution APM
reponame_str São Paulo medical journal (Online)
collection São Paulo medical journal (Online)
repository.name.fl_str_mv São Paulo medical journal (Online) - Associação Paulista de Medicina
repository.mail.fl_str_mv revistas@apm.org.br
_version_ 1754209259586846720

Registros relacionados