Roles of certain biochemical and hematological parameters in predicting mortality and ICU admission in COVID-19 patients
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista da Associação Médica Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302021000200067 |
Resumo: | SUMMARY OBJECTIVE: In this study, we aimed to retrospectively analyze the roles of certain hematological and biochemical parameters in predicting mortality and intensive care unit admission in patients diagnosed with coronavirus disease 2019 (COVID-19). METHODS: We analyzed the complete blood count and biochemical parameters of 186 COVID-19 patients by using the polymerase chain reaction test. Whether these parameters can be used to predict intensive care unit admission and mortality in the COVID-19 patients was investigated. RESULTS: The complete blood count and biochemical parameters of COVID-19 patients and in those admitted to intensive care unit were compared. The red cell distribution width, ferritin, lactate dehydrogenase, D-dimer, C-reactive protein, prothrombin time, and creatinine levels were found to be the most significant parameters. We found that these parameters are significant for predicting not only intensive care unit admission, but also the mortality of the patients admitted to the intensive care unit. CONCLUSIONS: We determined that the most effective parameters to predict intensive care unit admission and mortality in COVID-19 patients are ferritin, lactate dehydrogenase, D-dimer, C-reactive protein, red cell distribution width, creatinine, and intensive care unit. Close monitoring of these parameters and early intervention in alterations are of vital importance. |
id |
AMB-1_cf9986be8cbdbb12b578e024f15c7564 |
---|---|
oai_identifier_str |
oai:scielo:S0104-42302021000200067 |
network_acronym_str |
AMB-1 |
network_name_str |
Revista da Associação Médica Brasileira (Online) |
repository_id_str |
|
spelling |
Roles of certain biochemical and hematological parameters in predicting mortality and ICU admission in COVID-19 patientsCoronavirus infectionsMortalityIntensive care unitBlood coagulationInternational normalized ratioFibrin fibrinogen degradation productsCreatinineC-reactive proteinErythrocyte indicesSUMMARY OBJECTIVE: In this study, we aimed to retrospectively analyze the roles of certain hematological and biochemical parameters in predicting mortality and intensive care unit admission in patients diagnosed with coronavirus disease 2019 (COVID-19). METHODS: We analyzed the complete blood count and biochemical parameters of 186 COVID-19 patients by using the polymerase chain reaction test. Whether these parameters can be used to predict intensive care unit admission and mortality in the COVID-19 patients was investigated. RESULTS: The complete blood count and biochemical parameters of COVID-19 patients and in those admitted to intensive care unit were compared. The red cell distribution width, ferritin, lactate dehydrogenase, D-dimer, C-reactive protein, prothrombin time, and creatinine levels were found to be the most significant parameters. We found that these parameters are significant for predicting not only intensive care unit admission, but also the mortality of the patients admitted to the intensive care unit. CONCLUSIONS: We determined that the most effective parameters to predict intensive care unit admission and mortality in COVID-19 patients are ferritin, lactate dehydrogenase, D-dimer, C-reactive protein, red cell distribution width, creatinine, and intensive care unit. Close monitoring of these parameters and early intervention in alterations are of vital importance.Associação Médica Brasileira2021-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302021000200067Revista da Associação Médica Brasileira v.67 suppl.1 2021reponame:Revista da Associação Médica Brasileira (Online)instname:Associação Médica Brasileira (AMB)instacron:AMB10.1590/1806-9282.67.suppl1.20200788info:eu-repo/semantics/openAccessBilgir,FerdaÇalık,ŞebnemDemir,İsmailBilgir,Oktayeng2021-08-19T00:00:00Zoai:scielo:S0104-42302021000200067Revistahttps://ramb.amb.org.br/ultimas-edicoes/#https://old.scielo.br/oai/scielo-oai.php||ramb@amb.org.br1806-92820104-4230opendoar:2021-08-19T00:00Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB)false |
dc.title.none.fl_str_mv |
Roles of certain biochemical and hematological parameters in predicting mortality and ICU admission in COVID-19 patients |
title |
Roles of certain biochemical and hematological parameters in predicting mortality and ICU admission in COVID-19 patients |
spellingShingle |
Roles of certain biochemical and hematological parameters in predicting mortality and ICU admission in COVID-19 patients Bilgir,Ferda Coronavirus infections Mortality Intensive care unit Blood coagulation International normalized ratio Fibrin fibrinogen degradation products Creatinine C-reactive protein Erythrocyte indices |
title_short |
Roles of certain biochemical and hematological parameters in predicting mortality and ICU admission in COVID-19 patients |
title_full |
Roles of certain biochemical and hematological parameters in predicting mortality and ICU admission in COVID-19 patients |
title_fullStr |
Roles of certain biochemical and hematological parameters in predicting mortality and ICU admission in COVID-19 patients |
title_full_unstemmed |
Roles of certain biochemical and hematological parameters in predicting mortality and ICU admission in COVID-19 patients |
title_sort |
Roles of certain biochemical and hematological parameters in predicting mortality and ICU admission in COVID-19 patients |
author |
Bilgir,Ferda |
author_facet |
Bilgir,Ferda Çalık,Şebnem Demir,İsmail Bilgir,Oktay |
author_role |
author |
author2 |
Çalık,Şebnem Demir,İsmail Bilgir,Oktay |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Bilgir,Ferda Çalık,Şebnem Demir,İsmail Bilgir,Oktay |
dc.subject.por.fl_str_mv |
Coronavirus infections Mortality Intensive care unit Blood coagulation International normalized ratio Fibrin fibrinogen degradation products Creatinine C-reactive protein Erythrocyte indices |
topic |
Coronavirus infections Mortality Intensive care unit Blood coagulation International normalized ratio Fibrin fibrinogen degradation products Creatinine C-reactive protein Erythrocyte indices |
description |
SUMMARY OBJECTIVE: In this study, we aimed to retrospectively analyze the roles of certain hematological and biochemical parameters in predicting mortality and intensive care unit admission in patients diagnosed with coronavirus disease 2019 (COVID-19). METHODS: We analyzed the complete blood count and biochemical parameters of 186 COVID-19 patients by using the polymerase chain reaction test. Whether these parameters can be used to predict intensive care unit admission and mortality in the COVID-19 patients was investigated. RESULTS: The complete blood count and biochemical parameters of COVID-19 patients and in those admitted to intensive care unit were compared. The red cell distribution width, ferritin, lactate dehydrogenase, D-dimer, C-reactive protein, prothrombin time, and creatinine levels were found to be the most significant parameters. We found that these parameters are significant for predicting not only intensive care unit admission, but also the mortality of the patients admitted to the intensive care unit. CONCLUSIONS: We determined that the most effective parameters to predict intensive care unit admission and mortality in COVID-19 patients are ferritin, lactate dehydrogenase, D-dimer, C-reactive protein, red cell distribution width, creatinine, and intensive care unit. Close monitoring of these parameters and early intervention in alterations are of vital importance. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302021000200067 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302021000200067 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1806-9282.67.suppl1.20200788 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Médica Brasileira |
publisher.none.fl_str_mv |
Associação Médica Brasileira |
dc.source.none.fl_str_mv |
Revista da Associação Médica Brasileira v.67 suppl.1 2021 reponame:Revista da Associação Médica Brasileira (Online) instname:Associação Médica Brasileira (AMB) instacron:AMB |
instname_str |
Associação Médica Brasileira (AMB) |
instacron_str |
AMB |
institution |
AMB |
reponame_str |
Revista da Associação Médica Brasileira (Online) |
collection |
Revista da Associação Médica Brasileira (Online) |
repository.name.fl_str_mv |
Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB) |
repository.mail.fl_str_mv |
||ramb@amb.org.br |
_version_ |
1754212836997857280 |