Efficacy and landscape of Covid-19 vaccines: a review article
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista da Associação Médica Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302021000400474 |
Resumo: | SUMMARY INTRODUCTION: The rapid advance of Coronavirus disease 2019 (Covid-19) has led to the incessant search for therapeutic and prophylactic measures to fight the pandemic. Because it is a viral infection, the safest long-term prophylactic form, in addition to social distance and hygiene, is the vaccine. OBJECTIVE: Thus, this study aimed at conducting a review of the efficacy and landscape of Covid-19 vaccines. METHODS: The following electronic databases were used MEDLINE via PubMed, SCIELO, LILACS, NEJM, and Clinical Trials. Our study includes the 7 vaccines (phase 3) that reported an efficacy rate for Covid-19, including characteristics inherent to each one of them. RESULTS: Preliminary studies have shown that, although an efficacy ≥70% is necessary to eliminate the infection, a prophylactic vaccine with efficacy <70% will still have an important impact and can contribute to the elimination of the virus, provided that appropriate measures of social distancing remain. CONCLUSIONS: The effectiveness of the vaccines obtained in this study varied between 50.38 and 95%, data that may represent a reduction in serious cases, hospitalizations, sequels, and deaths caused by Covid-19, respecting the panorama presented in this article. |
id |
AMB-1_f71da75aa34b37c51da9c75cfcac744f |
---|---|
oai_identifier_str |
oai:scielo:S0104-42302021000400474 |
network_acronym_str |
AMB-1 |
network_name_str |
Revista da Associação Médica Brasileira (Online) |
repository_id_str |
|
spelling |
Efficacy and landscape of Covid-19 vaccines: a review articleCovid-19VaccinesEfficacySUMMARY INTRODUCTION: The rapid advance of Coronavirus disease 2019 (Covid-19) has led to the incessant search for therapeutic and prophylactic measures to fight the pandemic. Because it is a viral infection, the safest long-term prophylactic form, in addition to social distance and hygiene, is the vaccine. OBJECTIVE: Thus, this study aimed at conducting a review of the efficacy and landscape of Covid-19 vaccines. METHODS: The following electronic databases were used MEDLINE via PubMed, SCIELO, LILACS, NEJM, and Clinical Trials. Our study includes the 7 vaccines (phase 3) that reported an efficacy rate for Covid-19, including characteristics inherent to each one of them. RESULTS: Preliminary studies have shown that, although an efficacy ≥70% is necessary to eliminate the infection, a prophylactic vaccine with efficacy <70% will still have an important impact and can contribute to the elimination of the virus, provided that appropriate measures of social distancing remain. CONCLUSIONS: The effectiveness of the vaccines obtained in this study varied between 50.38 and 95%, data that may represent a reduction in serious cases, hospitalizations, sequels, and deaths caused by Covid-19, respecting the panorama presented in this article.Associação Médica Brasileira2021-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302021000400474Revista da Associação Médica Brasileira v.67 n.3 2021reponame:Revista da Associação Médica Brasileira (Online)instname:Associação Médica Brasileira (AMB)instacron:AMB10.1590/1806-9282.20210073info:eu-repo/semantics/openAccessAzevedo,Thomás Cavalcanti Pires deFreitas,Pedro Vianna deCunha,Pedro Henrique Padilha daMoreira,Eraldo Abillio PereiraRocha,Thiago José MatosBarbosa,Fabiano TimbóSousa-Rodrigues,Célio Fernando deRamos,Fernando Wagner da Silvaeng2021-08-24T00:00:00Zoai:scielo:S0104-42302021000400474Revistahttps://ramb.amb.org.br/ultimas-edicoes/#https://old.scielo.br/oai/scielo-oai.php||ramb@amb.org.br1806-92820104-4230opendoar:2021-08-24T00:00Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB)false |
dc.title.none.fl_str_mv |
Efficacy and landscape of Covid-19 vaccines: a review article |
title |
Efficacy and landscape of Covid-19 vaccines: a review article |
spellingShingle |
Efficacy and landscape of Covid-19 vaccines: a review article Azevedo,Thomás Cavalcanti Pires de Covid-19 Vaccines Efficacy |
title_short |
Efficacy and landscape of Covid-19 vaccines: a review article |
title_full |
Efficacy and landscape of Covid-19 vaccines: a review article |
title_fullStr |
Efficacy and landscape of Covid-19 vaccines: a review article |
title_full_unstemmed |
Efficacy and landscape of Covid-19 vaccines: a review article |
title_sort |
Efficacy and landscape of Covid-19 vaccines: a review article |
author |
Azevedo,Thomás Cavalcanti Pires de |
author_facet |
Azevedo,Thomás Cavalcanti Pires de Freitas,Pedro Vianna de Cunha,Pedro Henrique Padilha da Moreira,Eraldo Abillio Pereira Rocha,Thiago José Matos Barbosa,Fabiano Timbó Sousa-Rodrigues,Célio Fernando de Ramos,Fernando Wagner da Silva |
author_role |
author |
author2 |
Freitas,Pedro Vianna de Cunha,Pedro Henrique Padilha da Moreira,Eraldo Abillio Pereira Rocha,Thiago José Matos Barbosa,Fabiano Timbó Sousa-Rodrigues,Célio Fernando de Ramos,Fernando Wagner da Silva |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Azevedo,Thomás Cavalcanti Pires de Freitas,Pedro Vianna de Cunha,Pedro Henrique Padilha da Moreira,Eraldo Abillio Pereira Rocha,Thiago José Matos Barbosa,Fabiano Timbó Sousa-Rodrigues,Célio Fernando de Ramos,Fernando Wagner da Silva |
dc.subject.por.fl_str_mv |
Covid-19 Vaccines Efficacy |
topic |
Covid-19 Vaccines Efficacy |
description |
SUMMARY INTRODUCTION: The rapid advance of Coronavirus disease 2019 (Covid-19) has led to the incessant search for therapeutic and prophylactic measures to fight the pandemic. Because it is a viral infection, the safest long-term prophylactic form, in addition to social distance and hygiene, is the vaccine. OBJECTIVE: Thus, this study aimed at conducting a review of the efficacy and landscape of Covid-19 vaccines. METHODS: The following electronic databases were used MEDLINE via PubMed, SCIELO, LILACS, NEJM, and Clinical Trials. Our study includes the 7 vaccines (phase 3) that reported an efficacy rate for Covid-19, including characteristics inherent to each one of them. RESULTS: Preliminary studies have shown that, although an efficacy ≥70% is necessary to eliminate the infection, a prophylactic vaccine with efficacy <70% will still have an important impact and can contribute to the elimination of the virus, provided that appropriate measures of social distancing remain. CONCLUSIONS: The effectiveness of the vaccines obtained in this study varied between 50.38 and 95%, data that may represent a reduction in serious cases, hospitalizations, sequels, and deaths caused by Covid-19, respecting the panorama presented in this article. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302021000400474 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302021000400474 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1806-9282.20210073 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Médica Brasileira |
publisher.none.fl_str_mv |
Associação Médica Brasileira |
dc.source.none.fl_str_mv |
Revista da Associação Médica Brasileira v.67 n.3 2021 reponame:Revista da Associação Médica Brasileira (Online) instname:Associação Médica Brasileira (AMB) instacron:AMB |
instname_str |
Associação Médica Brasileira (AMB) |
instacron_str |
AMB |
institution |
AMB |
reponame_str |
Revista da Associação Médica Brasileira (Online) |
collection |
Revista da Associação Médica Brasileira (Online) |
repository.name.fl_str_mv |
Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB) |
repository.mail.fl_str_mv |
||ramb@amb.org.br |
_version_ |
1754212836098179072 |