How stress mediators can cumulatively contribute to Alzheimer’s disease An allostatic load approach

Detalhes bibliográficos
Autor(a) principal: Matos,Tatiane Martins
Data de Publicação: 2019
Outros Autores: Souza-Talarico,Juliana Nery De
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Dementia & Neuropsychologia
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642019000100011
Resumo: ABSTRACT. Allostatic load is defined as the frequent activation of the neuroendocrine, immunological, metabolic and cardiovascular systems, which makes individuals more susceptible to stress-related health problems. According to this model, physiological dysregulations start to emerge decades before diseases manifest. Consequently, stress research has shifted its attention to anticipating the degree of this dysregulation to better understand the impact of stress hormones and other biomarkers on disease progression. In view of the growing number of studies that demonstrate the influence of modifiable risk factors on cognitive decline, in addition to the effects of chronic stress mediators, the objective of the present review was to present an overview of the development of cognitive changes based on studies on stress and its mediators.
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spelling How stress mediators can cumulatively contribute to Alzheimer’s disease An allostatic load approachstressAlzheimer’s diseaseallostatic loadcognitive declinememoryABSTRACT. Allostatic load is defined as the frequent activation of the neuroendocrine, immunological, metabolic and cardiovascular systems, which makes individuals more susceptible to stress-related health problems. According to this model, physiological dysregulations start to emerge decades before diseases manifest. Consequently, stress research has shifted its attention to anticipating the degree of this dysregulation to better understand the impact of stress hormones and other biomarkers on disease progression. In view of the growing number of studies that demonstrate the influence of modifiable risk factors on cognitive decline, in addition to the effects of chronic stress mediators, the objective of the present review was to present an overview of the development of cognitive changes based on studies on stress and its mediators.Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento2019-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642019000100011Dementia & Neuropsychologia v.13 n.1 2019reponame:Dementia & Neuropsychologiainstname:Associação de Neurologia Cognitiva e do Comportamento (ANCC)instacron:ANCC10.1590/1980-57642018dn13-010002info:eu-repo/semantics/openAccessMatos,Tatiane MartinsSouza-Talarico,Juliana Nery Deeng2019-03-27T00:00:00Zoai:scielo:S1980-57642019000100011Revistahttp://www.demneuropsy.com.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||demneuropsy@uol.com.br1980-57641980-5764opendoar:2019-03-27T00:00Dementia & Neuropsychologia - Associação de Neurologia Cognitiva e do Comportamento (ANCC)false
dc.title.none.fl_str_mv How stress mediators can cumulatively contribute to Alzheimer’s disease An allostatic load approach
title How stress mediators can cumulatively contribute to Alzheimer’s disease An allostatic load approach
spellingShingle How stress mediators can cumulatively contribute to Alzheimer’s disease An allostatic load approach
Matos,Tatiane Martins
stress
Alzheimer’s disease
allostatic load
cognitive decline
memory
title_short How stress mediators can cumulatively contribute to Alzheimer’s disease An allostatic load approach
title_full How stress mediators can cumulatively contribute to Alzheimer’s disease An allostatic load approach
title_fullStr How stress mediators can cumulatively contribute to Alzheimer’s disease An allostatic load approach
title_full_unstemmed How stress mediators can cumulatively contribute to Alzheimer’s disease An allostatic load approach
title_sort How stress mediators can cumulatively contribute to Alzheimer’s disease An allostatic load approach
author Matos,Tatiane Martins
author_facet Matos,Tatiane Martins
Souza-Talarico,Juliana Nery De
author_role author
author2 Souza-Talarico,Juliana Nery De
author2_role author
dc.contributor.author.fl_str_mv Matos,Tatiane Martins
Souza-Talarico,Juliana Nery De
dc.subject.por.fl_str_mv stress
Alzheimer’s disease
allostatic load
cognitive decline
memory
topic stress
Alzheimer’s disease
allostatic load
cognitive decline
memory
description ABSTRACT. Allostatic load is defined as the frequent activation of the neuroendocrine, immunological, metabolic and cardiovascular systems, which makes individuals more susceptible to stress-related health problems. According to this model, physiological dysregulations start to emerge decades before diseases manifest. Consequently, stress research has shifted its attention to anticipating the degree of this dysregulation to better understand the impact of stress hormones and other biomarkers on disease progression. In view of the growing number of studies that demonstrate the influence of modifiable risk factors on cognitive decline, in addition to the effects of chronic stress mediators, the objective of the present review was to present an overview of the development of cognitive changes based on studies on stress and its mediators.
publishDate 2019
dc.date.none.fl_str_mv 2019-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642019000100011
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642019000100011
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1980-57642018dn13-010002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
publisher.none.fl_str_mv Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
dc.source.none.fl_str_mv Dementia & Neuropsychologia v.13 n.1 2019
reponame:Dementia & Neuropsychologia
instname:Associação de Neurologia Cognitiva e do Comportamento (ANCC)
instacron:ANCC
instname_str Associação de Neurologia Cognitiva e do Comportamento (ANCC)
instacron_str ANCC
institution ANCC
reponame_str Dementia & Neuropsychologia
collection Dementia & Neuropsychologia
repository.name.fl_str_mv Dementia & Neuropsychologia - Associação de Neurologia Cognitiva e do Comportamento (ANCC)
repository.mail.fl_str_mv ||demneuropsy@uol.com.br
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