Cognitive impairment in patients with clinically isolated syndrome

Detalhes bibliográficos
Autor(a) principal: Anhoque,Carolina Fiorin
Data de Publicação: 2012
Outros Autores: Biccas Neto,Laurentino, Domingues,Simone Cristina Aires, Teixeira,Antônio Lúcio, Domingues,Renan Barros
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Dementia & Neuropsychologia
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642012000400266
Resumo: ABSTRACT Cognitive abnormalities have been extensively studied in Multiple Sclerosis (MS). However, little is known about the cognitive involvement in patients with Clinically Isolated Syndrome (CIS). Objective: This study aimed to investigate cognitive impairment in patients with CIS compared with healthy subjects. Methods: 18 CIS patients and 18 controls were subjected to the Wechsler memory scale, Rey Auditory Verbal Learning, Rey Complex Figure, Paced Auditory Serial Addition, Digit Span, verbal fluency, Stroop color card test, D2, and Digit Symbol tests. Results: CIS patients had significantly worse performance on the Paced Auditory Serial Addition Test (PASAT) 2 seconds (P=0.009) and on verbal fluency tests (P=0.0038) than controls. Conclusion: CIS patients had worse cognitive performance than controls on neuropsychological tests evaluating executive functioning.
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spelling Cognitive impairment in patients with clinically isolated syndromecognitionclinically isolated syndromeneuropsychological testsABSTRACT Cognitive abnormalities have been extensively studied in Multiple Sclerosis (MS). However, little is known about the cognitive involvement in patients with Clinically Isolated Syndrome (CIS). Objective: This study aimed to investigate cognitive impairment in patients with CIS compared with healthy subjects. Methods: 18 CIS patients and 18 controls were subjected to the Wechsler memory scale, Rey Auditory Verbal Learning, Rey Complex Figure, Paced Auditory Serial Addition, Digit Span, verbal fluency, Stroop color card test, D2, and Digit Symbol tests. Results: CIS patients had significantly worse performance on the Paced Auditory Serial Addition Test (PASAT) 2 seconds (P=0.009) and on verbal fluency tests (P=0.0038) than controls. Conclusion: CIS patients had worse cognitive performance than controls on neuropsychological tests evaluating executive functioning.Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento2012-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642012000400266Dementia & Neuropsychologia v.6 n.4 2012reponame:Dementia & Neuropsychologiainstname:Associação de Neurologia Cognitiva e do Comportamento (ANCC)instacron:ANCC10.1590/S1980-57642012DN06040011info:eu-repo/semantics/openAccessAnhoque,Carolina FiorinBiccas Neto,LaurentinoDomingues,Simone Cristina AiresTeixeira,Antônio LúcioDomingues,Renan Barroseng2016-07-15T00:00:00Zoai:scielo:S1980-57642012000400266Revistahttp://www.demneuropsy.com.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||demneuropsy@uol.com.br1980-57641980-5764opendoar:2016-07-15T00:00Dementia & Neuropsychologia - Associação de Neurologia Cognitiva e do Comportamento (ANCC)false
dc.title.none.fl_str_mv Cognitive impairment in patients with clinically isolated syndrome
title Cognitive impairment in patients with clinically isolated syndrome
spellingShingle Cognitive impairment in patients with clinically isolated syndrome
Anhoque,Carolina Fiorin
cognition
clinically isolated syndrome
neuropsychological tests
title_short Cognitive impairment in patients with clinically isolated syndrome
title_full Cognitive impairment in patients with clinically isolated syndrome
title_fullStr Cognitive impairment in patients with clinically isolated syndrome
title_full_unstemmed Cognitive impairment in patients with clinically isolated syndrome
title_sort Cognitive impairment in patients with clinically isolated syndrome
author Anhoque,Carolina Fiorin
author_facet Anhoque,Carolina Fiorin
Biccas Neto,Laurentino
Domingues,Simone Cristina Aires
Teixeira,Antônio Lúcio
Domingues,Renan Barros
author_role author
author2 Biccas Neto,Laurentino
Domingues,Simone Cristina Aires
Teixeira,Antônio Lúcio
Domingues,Renan Barros
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Anhoque,Carolina Fiorin
Biccas Neto,Laurentino
Domingues,Simone Cristina Aires
Teixeira,Antônio Lúcio
Domingues,Renan Barros
dc.subject.por.fl_str_mv cognition
clinically isolated syndrome
neuropsychological tests
topic cognition
clinically isolated syndrome
neuropsychological tests
description ABSTRACT Cognitive abnormalities have been extensively studied in Multiple Sclerosis (MS). However, little is known about the cognitive involvement in patients with Clinically Isolated Syndrome (CIS). Objective: This study aimed to investigate cognitive impairment in patients with CIS compared with healthy subjects. Methods: 18 CIS patients and 18 controls were subjected to the Wechsler memory scale, Rey Auditory Verbal Learning, Rey Complex Figure, Paced Auditory Serial Addition, Digit Span, verbal fluency, Stroop color card test, D2, and Digit Symbol tests. Results: CIS patients had significantly worse performance on the Paced Auditory Serial Addition Test (PASAT) 2 seconds (P=0.009) and on verbal fluency tests (P=0.0038) than controls. Conclusion: CIS patients had worse cognitive performance than controls on neuropsychological tests evaluating executive functioning.
publishDate 2012
dc.date.none.fl_str_mv 2012-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642012000400266
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642012000400266
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1980-57642012DN06040011
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
publisher.none.fl_str_mv Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
dc.source.none.fl_str_mv Dementia & Neuropsychologia v.6 n.4 2012
reponame:Dementia & Neuropsychologia
instname:Associação de Neurologia Cognitiva e do Comportamento (ANCC)
instacron:ANCC
instname_str Associação de Neurologia Cognitiva e do Comportamento (ANCC)
instacron_str ANCC
institution ANCC
reponame_str Dementia & Neuropsychologia
collection Dementia & Neuropsychologia
repository.name.fl_str_mv Dementia & Neuropsychologia - Associação de Neurologia Cognitiva e do Comportamento (ANCC)
repository.mail.fl_str_mv ||demneuropsy@uol.com.br
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