Early and severe cognitive impairment in multiple sclerosis

Detalhes bibliográficos
Autor(a) principal: Mendes,Maria Fernanda
Data de Publicação: 2012
Outros Autores: Finkelsztejn,Alessandro, Gomes,Sidney, Fragoso,Yára Dadalti
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Dementia & Neuropsychologia
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642012000100048
Resumo: ABSTRACT Objectives: To report on four new cases of severe cognitive impairment in the early stages of multiple sclerosis (MS) and to review data on the subject since few cases have been reported worldwide. Methods: Retrospective evaluation of medical records of patients with severe cognitive impairment within the first five years of MS diagnosis. Results on neuropsychological tests and magnetic resonance imaging (MRI) were disclosed. Results: Four patients from different Brazilian neurological departments in Brazil were evaluated, all presenting with severe cognitive dysfunction classified as rapidly developing dementia. MRI images showed severe brain atrophy and basal ganglia lesions in all patients. Conclusions: Although rare, severe cognitive impairment in MS represents an important disability and may ultimately constitute another form of the disease.
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spelling Early and severe cognitive impairment in multiple sclerosismultiple sclerosiscognitiondementiabasal gangliabrain atrophyABSTRACT Objectives: To report on four new cases of severe cognitive impairment in the early stages of multiple sclerosis (MS) and to review data on the subject since few cases have been reported worldwide. Methods: Retrospective evaluation of medical records of patients with severe cognitive impairment within the first five years of MS diagnosis. Results on neuropsychological tests and magnetic resonance imaging (MRI) were disclosed. Results: Four patients from different Brazilian neurological departments in Brazil were evaluated, all presenting with severe cognitive dysfunction classified as rapidly developing dementia. MRI images showed severe brain atrophy and basal ganglia lesions in all patients. Conclusions: Although rare, severe cognitive impairment in MS represents an important disability and may ultimately constitute another form of the disease.Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento2012-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642012000100048Dementia & Neuropsychologia v.6 n.1 2012reponame:Dementia & Neuropsychologiainstname:Associação de Neurologia Cognitiva e do Comportamento (ANCC)instacron:ANCC10.1590/S1980-57642012DN06010008info:eu-repo/semantics/openAccessMendes,Maria FernandaFinkelsztejn,AlessandroGomes,SidneyFragoso,Yára Dadaltieng2016-07-20T00:00:00Zoai:scielo:S1980-57642012000100048Revistahttp://www.demneuropsy.com.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||demneuropsy@uol.com.br1980-57641980-5764opendoar:2016-07-20T00:00Dementia & Neuropsychologia - Associação de Neurologia Cognitiva e do Comportamento (ANCC)false
dc.title.none.fl_str_mv Early and severe cognitive impairment in multiple sclerosis
title Early and severe cognitive impairment in multiple sclerosis
spellingShingle Early and severe cognitive impairment in multiple sclerosis
Mendes,Maria Fernanda
multiple sclerosis
cognition
dementia
basal ganglia
brain atrophy
title_short Early and severe cognitive impairment in multiple sclerosis
title_full Early and severe cognitive impairment in multiple sclerosis
title_fullStr Early and severe cognitive impairment in multiple sclerosis
title_full_unstemmed Early and severe cognitive impairment in multiple sclerosis
title_sort Early and severe cognitive impairment in multiple sclerosis
author Mendes,Maria Fernanda
author_facet Mendes,Maria Fernanda
Finkelsztejn,Alessandro
Gomes,Sidney
Fragoso,Yára Dadalti
author_role author
author2 Finkelsztejn,Alessandro
Gomes,Sidney
Fragoso,Yára Dadalti
author2_role author
author
author
dc.contributor.author.fl_str_mv Mendes,Maria Fernanda
Finkelsztejn,Alessandro
Gomes,Sidney
Fragoso,Yára Dadalti
dc.subject.por.fl_str_mv multiple sclerosis
cognition
dementia
basal ganglia
brain atrophy
topic multiple sclerosis
cognition
dementia
basal ganglia
brain atrophy
description ABSTRACT Objectives: To report on four new cases of severe cognitive impairment in the early stages of multiple sclerosis (MS) and to review data on the subject since few cases have been reported worldwide. Methods: Retrospective evaluation of medical records of patients with severe cognitive impairment within the first five years of MS diagnosis. Results on neuropsychological tests and magnetic resonance imaging (MRI) were disclosed. Results: Four patients from different Brazilian neurological departments in Brazil were evaluated, all presenting with severe cognitive dysfunction classified as rapidly developing dementia. MRI images showed severe brain atrophy and basal ganglia lesions in all patients. Conclusions: Although rare, severe cognitive impairment in MS represents an important disability and may ultimately constitute another form of the disease.
publishDate 2012
dc.date.none.fl_str_mv 2012-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642012000100048
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642012000100048
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1980-57642012DN06010008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
publisher.none.fl_str_mv Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
dc.source.none.fl_str_mv Dementia & Neuropsychologia v.6 n.1 2012
reponame:Dementia & Neuropsychologia
instname:Associação de Neurologia Cognitiva e do Comportamento (ANCC)
instacron:ANCC
instname_str Associação de Neurologia Cognitiva e do Comportamento (ANCC)
instacron_str ANCC
institution ANCC
reponame_str Dementia & Neuropsychologia
collection Dementia & Neuropsychologia
repository.name.fl_str_mv Dementia & Neuropsychologia - Associação de Neurologia Cognitiva e do Comportamento (ANCC)
repository.mail.fl_str_mv ||demneuropsy@uol.com.br
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