Spinal cord compression in b-thalassemia: follow-up after radiotherapy

Detalhes bibliográficos
Autor(a) principal: Fonseca,Silvana Fahel da
Data de Publicação: 1998
Outros Autores: Figueiredo,Maria Stella, Cançado,Rodolfo Delfini, Nakandakare,Fernando, Segreto,Roberto, Kerbauy,José
Tipo de documento: Relatório
Idioma: eng
Título da fonte: São Paulo medical journal (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801998000600009
Resumo: CONTEXT: Spinal cord compression due to extramedullary hematopoiesis is a well-described but rare syndrome encountered in several clinical hematologic disorders, including <FONT FACE="Symbol">b</font>-thalassemia. CASE REPORT: We report the case of a patient with intermediate <FONT FACE="Symbol">b</font>-thalassemia and crural paraparesis due to spinal cord compression by a paravertebral extramedullary mass. She was successfully treated with low-dose radiotherapy and transfusions. After splenectomy, she was regularly followed up for over four years without transfusion or recurrence of spinal cord compression. DISCUSSION: Extramedullary hematopoiesis should be investigated in patients with hematologic disorders and spinal cord symptoms. The rapid recognition and treatment with radiotherapy can dramatically alleviate symptoms.
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spelling Spinal cord compression in b-thalassemia: follow-up after radiotherapyExtramedullary hematopoiesisSpinal cord compressionIntermediate <FONT FACE=Symbol>b</font>-thalassemiaCONTEXT: Spinal cord compression due to extramedullary hematopoiesis is a well-described but rare syndrome encountered in several clinical hematologic disorders, including <FONT FACE="Symbol">b</font>-thalassemia. CASE REPORT: We report the case of a patient with intermediate <FONT FACE="Symbol">b</font>-thalassemia and crural paraparesis due to spinal cord compression by a paravertebral extramedullary mass. She was successfully treated with low-dose radiotherapy and transfusions. After splenectomy, she was regularly followed up for over four years without transfusion or recurrence of spinal cord compression. DISCUSSION: Extramedullary hematopoiesis should be investigated in patients with hematologic disorders and spinal cord symptoms. The rapid recognition and treatment with radiotherapy can dramatically alleviate symptoms.Associação Paulista de Medicina - APM1998-11-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801998000600009Sao Paulo Medical Journal v.116 n.6 1998reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APM10.1590/S1516-31801998000600009info:eu-repo/semantics/openAccessFonseca,Silvana Fahel daFigueiredo,Maria StellaCançado,Rodolfo DelfiniNakandakare,FernandoSegreto,RobertoKerbauy,Joséeng1999-12-17T00:00:00Zoai:scielo:S1516-31801998000600009Revistahttp://www.scielo.br/spmjhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:1999-12-17T00:00São Paulo medical journal (Online) - Associação Paulista de Medicinafalse
dc.title.none.fl_str_mv Spinal cord compression in b-thalassemia: follow-up after radiotherapy
title Spinal cord compression in b-thalassemia: follow-up after radiotherapy
spellingShingle Spinal cord compression in b-thalassemia: follow-up after radiotherapy
Fonseca,Silvana Fahel da
Extramedullary hematopoiesis
Spinal cord compression
Intermediate <FONT FACE=Symbol>b</font>-thalassemia
title_short Spinal cord compression in b-thalassemia: follow-up after radiotherapy
title_full Spinal cord compression in b-thalassemia: follow-up after radiotherapy
title_fullStr Spinal cord compression in b-thalassemia: follow-up after radiotherapy
title_full_unstemmed Spinal cord compression in b-thalassemia: follow-up after radiotherapy
title_sort Spinal cord compression in b-thalassemia: follow-up after radiotherapy
author Fonseca,Silvana Fahel da
author_facet Fonseca,Silvana Fahel da
Figueiredo,Maria Stella
Cançado,Rodolfo Delfini
Nakandakare,Fernando
Segreto,Roberto
Kerbauy,José
author_role author
author2 Figueiredo,Maria Stella
Cançado,Rodolfo Delfini
Nakandakare,Fernando
Segreto,Roberto
Kerbauy,José
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Fonseca,Silvana Fahel da
Figueiredo,Maria Stella
Cançado,Rodolfo Delfini
Nakandakare,Fernando
Segreto,Roberto
Kerbauy,José
dc.subject.por.fl_str_mv Extramedullary hematopoiesis
Spinal cord compression
Intermediate <FONT FACE=Symbol>b</font>-thalassemia
topic Extramedullary hematopoiesis
Spinal cord compression
Intermediate <FONT FACE=Symbol>b</font>-thalassemia
description CONTEXT: Spinal cord compression due to extramedullary hematopoiesis is a well-described but rare syndrome encountered in several clinical hematologic disorders, including <FONT FACE="Symbol">b</font>-thalassemia. CASE REPORT: We report the case of a patient with intermediate <FONT FACE="Symbol">b</font>-thalassemia and crural paraparesis due to spinal cord compression by a paravertebral extramedullary mass. She was successfully treated with low-dose radiotherapy and transfusions. After splenectomy, she was regularly followed up for over four years without transfusion or recurrence of spinal cord compression. DISCUSSION: Extramedullary hematopoiesis should be investigated in patients with hematologic disorders and spinal cord symptoms. The rapid recognition and treatment with radiotherapy can dramatically alleviate symptoms.
publishDate 1998
dc.date.none.fl_str_mv 1998-11-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801998000600009
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801998000600009
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-31801998000600009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Paulista de Medicina - APM
publisher.none.fl_str_mv Associação Paulista de Medicina - APM
dc.source.none.fl_str_mv Sao Paulo Medical Journal v.116 n.6 1998
reponame:São Paulo medical journal (Online)
instname:Associação Paulista de Medicina
instacron:APM
instname_str Associação Paulista de Medicina
instacron_str APM
institution APM
reponame_str São Paulo medical journal (Online)
collection São Paulo medical journal (Online)
repository.name.fl_str_mv São Paulo medical journal (Online) - Associação Paulista de Medicina
repository.mail.fl_str_mv revistas@apm.org.br
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