a-Interferon therapy for HBV-related glomerulonephritis

Detalhes bibliográficos
Autor(a) principal: Lopes Neto,Edmundo Pessoa de Almeida
Data de Publicação: 1998
Outros Autores: Lopes,Lucila Valente, Kirsztajn,Gianna Mastroianni, Cruz,Cibele Nascimento, Ferraz,Maria Lucia Gomes, Silva,Antonio Eduardo Benedito
Tipo de documento: Relatório
Idioma: eng
Título da fonte: São Paulo medical journal (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801998000500008
Resumo: We report a case of a patient with hepatitis B virus (HBV)-related membranous glomerulonephritis (MGN) who showed improvement after interferon-<FONT FACE="Symbol">a</FONT> (IFN-<FONT FACE="Symbol">a</FONT>) therapy. A 35-year-old man with nephrotic syndrome and HBV antigens received a 24-week course of IFN-<FONT FACE="Symbol">a</FONT>. At the end of therapy there was an elevation in the level of plasma aminotransferase and an increase in proteinuria, which were followed by antigen/antibody seroconversion. This "flare-up" before seroconversion suggests an increase in disease activity in the liver and kidney, demonstrating in vivo HBV involvement in MGN.
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spelling a-Interferon therapy for HBV-related glomerulonephritisHepatitis B virusMembranous glomerulonephritisInterferonWe report a case of a patient with hepatitis B virus (HBV)-related membranous glomerulonephritis (MGN) who showed improvement after interferon-<FONT FACE="Symbol">a</FONT> (IFN-<FONT FACE="Symbol">a</FONT>) therapy. A 35-year-old man with nephrotic syndrome and HBV antigens received a 24-week course of IFN-<FONT FACE="Symbol">a</FONT>. At the end of therapy there was an elevation in the level of plasma aminotransferase and an increase in proteinuria, which were followed by antigen/antibody seroconversion. This "flare-up" before seroconversion suggests an increase in disease activity in the liver and kidney, demonstrating in vivo HBV involvement in MGN.Associação Paulista de Medicina - APM1998-09-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801998000500008Sao Paulo Medical Journal v.116 n.5 1998reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APM10.1590/S1516-31801998000500008info:eu-repo/semantics/openAccessLopes Neto,Edmundo Pessoa de AlmeidaLopes,Lucila ValenteKirsztajn,Gianna MastroianniCruz,Cibele NascimentoFerraz,Maria Lucia GomesSilva,Antonio Eduardo Beneditoeng1999-12-17T00:00:00Zoai:scielo:S1516-31801998000500008Revistahttp://www.scielo.br/spmjhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:1999-12-17T00:00São Paulo medical journal (Online) - Associação Paulista de Medicinafalse
dc.title.none.fl_str_mv a-Interferon therapy for HBV-related glomerulonephritis
title a-Interferon therapy for HBV-related glomerulonephritis
spellingShingle a-Interferon therapy for HBV-related glomerulonephritis
Lopes Neto,Edmundo Pessoa de Almeida
Hepatitis B virus
Membranous glomerulonephritis
Interferon
title_short a-Interferon therapy for HBV-related glomerulonephritis
title_full a-Interferon therapy for HBV-related glomerulonephritis
title_fullStr a-Interferon therapy for HBV-related glomerulonephritis
title_full_unstemmed a-Interferon therapy for HBV-related glomerulonephritis
title_sort a-Interferon therapy for HBV-related glomerulonephritis
author Lopes Neto,Edmundo Pessoa de Almeida
author_facet Lopes Neto,Edmundo Pessoa de Almeida
Lopes,Lucila Valente
Kirsztajn,Gianna Mastroianni
Cruz,Cibele Nascimento
Ferraz,Maria Lucia Gomes
Silva,Antonio Eduardo Benedito
author_role author
author2 Lopes,Lucila Valente
Kirsztajn,Gianna Mastroianni
Cruz,Cibele Nascimento
Ferraz,Maria Lucia Gomes
Silva,Antonio Eduardo Benedito
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Lopes Neto,Edmundo Pessoa de Almeida
Lopes,Lucila Valente
Kirsztajn,Gianna Mastroianni
Cruz,Cibele Nascimento
Ferraz,Maria Lucia Gomes
Silva,Antonio Eduardo Benedito
dc.subject.por.fl_str_mv Hepatitis B virus
Membranous glomerulonephritis
Interferon
topic Hepatitis B virus
Membranous glomerulonephritis
Interferon
description We report a case of a patient with hepatitis B virus (HBV)-related membranous glomerulonephritis (MGN) who showed improvement after interferon-<FONT FACE="Symbol">a</FONT> (IFN-<FONT FACE="Symbol">a</FONT>) therapy. A 35-year-old man with nephrotic syndrome and HBV antigens received a 24-week course of IFN-<FONT FACE="Symbol">a</FONT>. At the end of therapy there was an elevation in the level of plasma aminotransferase and an increase in proteinuria, which were followed by antigen/antibody seroconversion. This "flare-up" before seroconversion suggests an increase in disease activity in the liver and kidney, demonstrating in vivo HBV involvement in MGN.
publishDate 1998
dc.date.none.fl_str_mv 1998-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801998000500008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801998000500008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-31801998000500008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Paulista de Medicina - APM
publisher.none.fl_str_mv Associação Paulista de Medicina - APM
dc.source.none.fl_str_mv Sao Paulo Medical Journal v.116 n.5 1998
reponame:São Paulo medical journal (Online)
instname:Associação Paulista de Medicina
instacron:APM
instname_str Associação Paulista de Medicina
instacron_str APM
institution APM
reponame_str São Paulo medical journal (Online)
collection São Paulo medical journal (Online)
repository.name.fl_str_mv São Paulo medical journal (Online) - Associação Paulista de Medicina
repository.mail.fl_str_mv revistas@apm.org.br
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