Association between osteoporosis and rheumatoid arthritis in women: a cross-sectional study

Detalhes bibliográficos
Autor(a) principal: Sarkis,Karin Sedó
Data de Publicação: 2009
Outros Autores: Salvador,Mariana Barbieri, Pinheiro,Marcelo Medeiros, Silva,Raissa Gomes, Zerbini,Cristiano Augusto, Martini,Lígia Araújo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: São Paulo medical journal (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802009000400007
Resumo: CONTEXT AND OBJECTIVES: Osteoporosis has frequently been observed in patients with rheumatoid arthritis. The present study was undertaken in order to evaluate factors associated with osteoporosis among women with rheumatoid arthritis. DESIGN AND SETTING: Cross-sectional study, carried out in a public hospital in São Paulo. METHODS: The participants were 83 women with rheumatoid arthritis (53.7 ± 10.0 years old). Bone mineral density (BMD) and body composition were measured by dual energy X-ray absorptiometry. The patients were divided into three groups according to BMD: group 1, normal BMD (n = 24); group 2, osteopenia (n = 38); and group 3, osteoporosis (n = 21). Tests were performed to compare differences in means and correlations, with adjustments for age, duration of disease and cumulative corticosteroid. The relationships between clinical factors, physical activity score, dietary intake, body composition and biochemical parameters were analyzed using linear regression models. RESULTS: Mean calcium, vitamin D and omega-6 intakes were lower than the recommendations. Associations were found between BMD and age, disease duration, parathyroid hormone concentration and fat intake. The linear regression model showed that being older, with more years of disease and lower weight were negatively correlated with BMD [Total femur = 0.552 + 0.06 (weight) + 0.019 (total physical activity) - 0.05 (age) - 0.003 (disease duration); R² = 48.1; P < 0.001]. CONCLUSION: The present study indicates that nutritional factors and body composition are associated with bone mass in women with rheumatoid arthritis.
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spelling Association between osteoporosis and rheumatoid arthritis in women: a cross-sectional studyRheumatoid arthritisOsteoporosisDietBody compositionPhysical activityParathyroid hormoneCONTEXT AND OBJECTIVES: Osteoporosis has frequently been observed in patients with rheumatoid arthritis. The present study was undertaken in order to evaluate factors associated with osteoporosis among women with rheumatoid arthritis. DESIGN AND SETTING: Cross-sectional study, carried out in a public hospital in São Paulo. METHODS: The participants were 83 women with rheumatoid arthritis (53.7 ± 10.0 years old). Bone mineral density (BMD) and body composition were measured by dual energy X-ray absorptiometry. The patients were divided into three groups according to BMD: group 1, normal BMD (n = 24); group 2, osteopenia (n = 38); and group 3, osteoporosis (n = 21). Tests were performed to compare differences in means and correlations, with adjustments for age, duration of disease and cumulative corticosteroid. The relationships between clinical factors, physical activity score, dietary intake, body composition and biochemical parameters were analyzed using linear regression models. RESULTS: Mean calcium, vitamin D and omega-6 intakes were lower than the recommendations. Associations were found between BMD and age, disease duration, parathyroid hormone concentration and fat intake. The linear regression model showed that being older, with more years of disease and lower weight were negatively correlated with BMD [Total femur = 0.552 + 0.06 (weight) + 0.019 (total physical activity) - 0.05 (age) - 0.003 (disease duration); R² = 48.1; P < 0.001]. CONCLUSION: The present study indicates that nutritional factors and body composition are associated with bone mass in women with rheumatoid arthritis.Associação Paulista de Medicina - APM2009-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802009000400007Sao Paulo Medical Journal v.127 n.4 2009reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APM10.1590/S1516-31802009000400007info:eu-repo/semantics/openAccessSarkis,Karin SedóSalvador,Mariana BarbieriPinheiro,Marcelo MedeirosSilva,Raissa GomesZerbini,Cristiano AugustoMartini,Lígia Araújoeng2009-12-07T00:00:00Zoai:scielo:S1516-31802009000400007Revistahttp://www.scielo.br/spmjhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2009-12-07T00:00São Paulo medical journal (Online) - Associação Paulista de Medicinafalse
dc.title.none.fl_str_mv Association between osteoporosis and rheumatoid arthritis in women: a cross-sectional study
title Association between osteoporosis and rheumatoid arthritis in women: a cross-sectional study
spellingShingle Association between osteoporosis and rheumatoid arthritis in women: a cross-sectional study
Sarkis,Karin Sedó
Rheumatoid arthritis
Osteoporosis
Diet
Body composition
Physical activity
Parathyroid hormone
title_short Association between osteoporosis and rheumatoid arthritis in women: a cross-sectional study
title_full Association between osteoporosis and rheumatoid arthritis in women: a cross-sectional study
title_fullStr Association between osteoporosis and rheumatoid arthritis in women: a cross-sectional study
title_full_unstemmed Association between osteoporosis and rheumatoid arthritis in women: a cross-sectional study
title_sort Association between osteoporosis and rheumatoid arthritis in women: a cross-sectional study
author Sarkis,Karin Sedó
author_facet Sarkis,Karin Sedó
Salvador,Mariana Barbieri
Pinheiro,Marcelo Medeiros
Silva,Raissa Gomes
Zerbini,Cristiano Augusto
Martini,Lígia Araújo
author_role author
author2 Salvador,Mariana Barbieri
Pinheiro,Marcelo Medeiros
Silva,Raissa Gomes
Zerbini,Cristiano Augusto
Martini,Lígia Araújo
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Sarkis,Karin Sedó
Salvador,Mariana Barbieri
Pinheiro,Marcelo Medeiros
Silva,Raissa Gomes
Zerbini,Cristiano Augusto
Martini,Lígia Araújo
dc.subject.por.fl_str_mv Rheumatoid arthritis
Osteoporosis
Diet
Body composition
Physical activity
Parathyroid hormone
topic Rheumatoid arthritis
Osteoporosis
Diet
Body composition
Physical activity
Parathyroid hormone
description CONTEXT AND OBJECTIVES: Osteoporosis has frequently been observed in patients with rheumatoid arthritis. The present study was undertaken in order to evaluate factors associated with osteoporosis among women with rheumatoid arthritis. DESIGN AND SETTING: Cross-sectional study, carried out in a public hospital in São Paulo. METHODS: The participants were 83 women with rheumatoid arthritis (53.7 ± 10.0 years old). Bone mineral density (BMD) and body composition were measured by dual energy X-ray absorptiometry. The patients were divided into three groups according to BMD: group 1, normal BMD (n = 24); group 2, osteopenia (n = 38); and group 3, osteoporosis (n = 21). Tests were performed to compare differences in means and correlations, with adjustments for age, duration of disease and cumulative corticosteroid. The relationships between clinical factors, physical activity score, dietary intake, body composition and biochemical parameters were analyzed using linear regression models. RESULTS: Mean calcium, vitamin D and omega-6 intakes were lower than the recommendations. Associations were found between BMD and age, disease duration, parathyroid hormone concentration and fat intake. The linear regression model showed that being older, with more years of disease and lower weight were negatively correlated with BMD [Total femur = 0.552 + 0.06 (weight) + 0.019 (total physical activity) - 0.05 (age) - 0.003 (disease duration); R² = 48.1; P < 0.001]. CONCLUSION: The present study indicates that nutritional factors and body composition are associated with bone mass in women with rheumatoid arthritis.
publishDate 2009
dc.date.none.fl_str_mv 2009-07-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802009000400007
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802009000400007
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-31802009000400007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Paulista de Medicina - APM
publisher.none.fl_str_mv Associação Paulista de Medicina - APM
dc.source.none.fl_str_mv Sao Paulo Medical Journal v.127 n.4 2009
reponame:São Paulo medical journal (Online)
instname:Associação Paulista de Medicina
instacron:APM
instname_str Associação Paulista de Medicina
instacron_str APM
institution APM
reponame_str São Paulo medical journal (Online)
collection São Paulo medical journal (Online)
repository.name.fl_str_mv São Paulo medical journal (Online) - Associação Paulista de Medicina
repository.mail.fl_str_mv revistas@apm.org.br
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