Effect of probiotics on the intestinal microbiota of preterm and low birth weight infants: systematic review
Autor(a) principal: | |
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Data de Publicação: | 2024 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Health Review |
Texto Completo: | https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/68287 |
Resumo: | Premature infants have an immature intestinal microbiota when compared to a full-term baby, colonized with a reduced number of beneficial bacterial species and, therefore, are more likely to have their microbiota populated by pathogenic species. The administration of probiotics can positively influence the intestinal colonization of premature babies. Thus, this study aimed to systematically review evidences of the effect of administering probiotics on the microbiota of premature newborns and their safety. It was designed as follows: population (premature newborns), intervention (probiotics), comparison (placebo or no treatment), outcome (changes in the microbiota of premature newborns), study type (randomized clinical trials). The studies were searched in the Cochrane Library, Medline via PubMed and Embase databases and, in a complementary way, through manual searches on Google Scholar and the Brazilian CAPES journal portal (www.periodicos.capes.gov.br). We included 23 studies involving 3,670 preterm infants, of which 65.2% (n=15) were classified as having a low risk of bias, 17.4% (n=4) with some risk of bias and 17.4% (n= 4) with high risk of bias. Probiotics have been used in order to colonize the intestinal microbiota. Finally, some Lactobacillus and Bifidobacterium strains tested seem to have benefits and safety for the microbiota and health of premature newborns. |
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Brazilian Journal of Health Review |
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Effect of probiotics on the intestinal microbiota of preterm and low birth weight infants: systematic revieweffectprobioticsprematuremicrobiotaBifidobacteriumLactobacillusPremature infants have an immature intestinal microbiota when compared to a full-term baby, colonized with a reduced number of beneficial bacterial species and, therefore, are more likely to have their microbiota populated by pathogenic species. The administration of probiotics can positively influence the intestinal colonization of premature babies. Thus, this study aimed to systematically review evidences of the effect of administering probiotics on the microbiota of premature newborns and their safety. It was designed as follows: population (premature newborns), intervention (probiotics), comparison (placebo or no treatment), outcome (changes in the microbiota of premature newborns), study type (randomized clinical trials). The studies were searched in the Cochrane Library, Medline via PubMed and Embase databases and, in a complementary way, through manual searches on Google Scholar and the Brazilian CAPES journal portal (www.periodicos.capes.gov.br). We included 23 studies involving 3,670 preterm infants, of which 65.2% (n=15) were classified as having a low risk of bias, 17.4% (n=4) with some risk of bias and 17.4% (n= 4) with high risk of bias. Probiotics have been used in order to colonize the intestinal microbiota. Finally, some Lactobacillus and Bifidobacterium strains tested seem to have benefits and safety for the microbiota and health of premature newborns.Brazilian Journals Publicações de Periódicos e Editora Ltda.2024-03-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/6828710.34119/bjhrv7n2-184Brazilian Journal of Health Review; Vol. 7 No. 2 (2024); e68287Brazilian Journal of Health Review; Vol. 7 Núm. 2 (2024); e68287Brazilian Journal of Health Review; v. 7 n. 2 (2024); e682872595-6825reponame:Brazilian Journal of Health Reviewinstname:Federação das Indústrias do Estado do Paraná (FIEP)instacron:BJRHenghttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/68287/48586Cardoso, Laressa RiosPereira, Letícia CerqueiraCardoso, Andressa RiosAndrade, Kaio Vinicius Freitas deSantos Junior, Manoelito Coelho dosinfo:eu-repo/semantics/openAccess2024-04-01T12:20:45Zoai:ojs2.ojs.brazilianjournals.com.br:article/68287Revistahttp://www.brazilianjournals.com/index.php/BJHR/indexPRIhttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/oai|| brazilianjhr@gmail.com2595-68252595-6825opendoar:2024-04-01T12:20:45Brazilian Journal of Health Review - Federação das Indústrias do Estado do Paraná (FIEP)false |
dc.title.none.fl_str_mv |
Effect of probiotics on the intestinal microbiota of preterm and low birth weight infants: systematic review |
title |
Effect of probiotics on the intestinal microbiota of preterm and low birth weight infants: systematic review |
spellingShingle |
Effect of probiotics on the intestinal microbiota of preterm and low birth weight infants: systematic review Cardoso, Laressa Rios effect probiotics premature microbiota Bifidobacterium Lactobacillus |
title_short |
Effect of probiotics on the intestinal microbiota of preterm and low birth weight infants: systematic review |
title_full |
Effect of probiotics on the intestinal microbiota of preterm and low birth weight infants: systematic review |
title_fullStr |
Effect of probiotics on the intestinal microbiota of preterm and low birth weight infants: systematic review |
title_full_unstemmed |
Effect of probiotics on the intestinal microbiota of preterm and low birth weight infants: systematic review |
title_sort |
Effect of probiotics on the intestinal microbiota of preterm and low birth weight infants: systematic review |
author |
Cardoso, Laressa Rios |
author_facet |
Cardoso, Laressa Rios Pereira, Letícia Cerqueira Cardoso, Andressa Rios Andrade, Kaio Vinicius Freitas de Santos Junior, Manoelito Coelho dos |
author_role |
author |
author2 |
Pereira, Letícia Cerqueira Cardoso, Andressa Rios Andrade, Kaio Vinicius Freitas de Santos Junior, Manoelito Coelho dos |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Cardoso, Laressa Rios Pereira, Letícia Cerqueira Cardoso, Andressa Rios Andrade, Kaio Vinicius Freitas de Santos Junior, Manoelito Coelho dos |
dc.subject.por.fl_str_mv |
effect probiotics premature microbiota Bifidobacterium Lactobacillus |
topic |
effect probiotics premature microbiota Bifidobacterium Lactobacillus |
description |
Premature infants have an immature intestinal microbiota when compared to a full-term baby, colonized with a reduced number of beneficial bacterial species and, therefore, are more likely to have their microbiota populated by pathogenic species. The administration of probiotics can positively influence the intestinal colonization of premature babies. Thus, this study aimed to systematically review evidences of the effect of administering probiotics on the microbiota of premature newborns and their safety. It was designed as follows: population (premature newborns), intervention (probiotics), comparison (placebo or no treatment), outcome (changes in the microbiota of premature newborns), study type (randomized clinical trials). The studies were searched in the Cochrane Library, Medline via PubMed and Embase databases and, in a complementary way, through manual searches on Google Scholar and the Brazilian CAPES journal portal (www.periodicos.capes.gov.br). We included 23 studies involving 3,670 preterm infants, of which 65.2% (n=15) were classified as having a low risk of bias, 17.4% (n=4) with some risk of bias and 17.4% (n= 4) with high risk of bias. Probiotics have been used in order to colonize the intestinal microbiota. Finally, some Lactobacillus and Bifidobacterium strains tested seem to have benefits and safety for the microbiota and health of premature newborns. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-03-22 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/68287 10.34119/bjhrv7n2-184 |
url |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/68287 |
identifier_str_mv |
10.34119/bjhrv7n2-184 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/68287/48586 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Brazilian Journals Publicações de Periódicos e Editora Ltda. |
publisher.none.fl_str_mv |
Brazilian Journals Publicações de Periódicos e Editora Ltda. |
dc.source.none.fl_str_mv |
Brazilian Journal of Health Review; Vol. 7 No. 2 (2024); e68287 Brazilian Journal of Health Review; Vol. 7 Núm. 2 (2024); e68287 Brazilian Journal of Health Review; v. 7 n. 2 (2024); e68287 2595-6825 reponame:Brazilian Journal of Health Review instname:Federação das Indústrias do Estado do Paraná (FIEP) instacron:BJRH |
instname_str |
Federação das Indústrias do Estado do Paraná (FIEP) |
instacron_str |
BJRH |
institution |
BJRH |
reponame_str |
Brazilian Journal of Health Review |
collection |
Brazilian Journal of Health Review |
repository.name.fl_str_mv |
Brazilian Journal of Health Review - Federação das Indústrias do Estado do Paraná (FIEP) |
repository.mail.fl_str_mv |
|| brazilianjhr@gmail.com |
_version_ |
1797240044702924800 |