Consequences on anthropometry and metabolism of offspring maintenance with low-protein diet since pregnancy to adult age / Consequências sobre a antropometria e o metabolismo em ratos submetidos a dieta com baixo teor de proteínas da gravidez até a idade adulta
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Health Review |
Texto Completo: | https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/50494 |
Resumo: | The pre and early post natal is a period high susceptible to environmental insults for instance nutrition. There is a high metabolic demand necessary for the multiplication and differentiation of cells for the formation of tissues and organs and unbalanced diets affect metabolism at long term. The present study aimed to analyze physiological and metabolic parameters in male offspring submitted to the low protein diet in the perinatal life followed by a normoprotein diet or kept on the same maternal low protein diet after weaning. 12 female Wistar rats were matched with male of same strainand according maternal diet forming normoproteic and low-protein groups during gestation and lactation. At weaning three groups were randomly formed: CC (control-control), LP (low-protein-low protein) and LPC (low-protein-control). Somatic growth, feed intake, organ weight, biochemical parameters, liver fat, blood cell count and glucose tolerance test were analysed. The post-weaning "nutritional recovery" diet improved body mass and longitudinal length. But, the maintenance with low protein diet post weaning caused weight and length deficiency (P<0.001). Other parameters such as food intake, murinometric measurements, fasting gliscemia, visceral fat, organ weight, OGTT and biochemical parameters observed in the LPC were similar to CC. The LP groups caused lower area under the glycemic curve, lower visceral fat, but similar blood count, tibial growth and liver fat compared to control. The parameters evaluated in offspring submitted to nutritional recovery corroborate previous study, but the maintenance of offspring with low protein diet minimizes catch-up growth, but alters metabolic response to glucose. |
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Consequences on anthropometry and metabolism of offspring maintenance with low-protein diet since pregnancy to adult age / Consequências sobre a antropometria e o metabolismo em ratos submetidos a dieta com baixo teor de proteínas da gravidez até a idade adultalow-protein dietcatch-up growthmetabolismorats.The pre and early post natal is a period high susceptible to environmental insults for instance nutrition. There is a high metabolic demand necessary for the multiplication and differentiation of cells for the formation of tissues and organs and unbalanced diets affect metabolism at long term. The present study aimed to analyze physiological and metabolic parameters in male offspring submitted to the low protein diet in the perinatal life followed by a normoprotein diet or kept on the same maternal low protein diet after weaning. 12 female Wistar rats were matched with male of same strainand according maternal diet forming normoproteic and low-protein groups during gestation and lactation. At weaning three groups were randomly formed: CC (control-control), LP (low-protein-low protein) and LPC (low-protein-control). Somatic growth, feed intake, organ weight, biochemical parameters, liver fat, blood cell count and glucose tolerance test were analysed. The post-weaning "nutritional recovery" diet improved body mass and longitudinal length. But, the maintenance with low protein diet post weaning caused weight and length deficiency (P<0.001). Other parameters such as food intake, murinometric measurements, fasting gliscemia, visceral fat, organ weight, OGTT and biochemical parameters observed in the LPC were similar to CC. The LP groups caused lower area under the glycemic curve, lower visceral fat, but similar blood count, tibial growth and liver fat compared to control. The parameters evaluated in offspring submitted to nutritional recovery corroborate previous study, but the maintenance of offspring with low protein diet minimizes catch-up growth, but alters metabolic response to glucose.Brazilian Journals Publicações de Periódicos e Editora Ltda.2022-07-21info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/5049410.34119/bjhrv5n4-093Brazilian Journal of Health Review; Vol. 5 No. 4 (2022); 13111-13129Brazilian Journal of Health Review; v. 5 n. 4 (2022); 13111-131292595-6825reponame:Brazilian Journal of Health Reviewinstname:Federação das Indústrias do Estado do Paraná (FIEP)instacron:BJRHenghttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/50494/pdfCopyright (c) 2022 Brazilian Journal of Health Reviewinfo:eu-repo/semantics/openAccessNascimento, Elizabeth doNeto, Laércio Marques da LuzAraújo, Nathália Cavalcanti de MoraisFranco, Eryvelton de SouzaMuniz, Giselia de Santana2022-08-31T17:59:52Zoai:ojs2.ojs.brazilianjournals.com.br:article/50494Revistahttp://www.brazilianjournals.com/index.php/BJHR/indexPRIhttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/oai|| brazilianjhr@gmail.com2595-68252595-6825opendoar:2022-08-31T17:59:52Brazilian Journal of Health Review - Federação das Indústrias do Estado do Paraná (FIEP)false |
dc.title.none.fl_str_mv |
Consequences on anthropometry and metabolism of offspring maintenance with low-protein diet since pregnancy to adult age / Consequências sobre a antropometria e o metabolismo em ratos submetidos a dieta com baixo teor de proteínas da gravidez até a idade adulta |
title |
Consequences on anthropometry and metabolism of offspring maintenance with low-protein diet since pregnancy to adult age / Consequências sobre a antropometria e o metabolismo em ratos submetidos a dieta com baixo teor de proteínas da gravidez até a idade adulta |
spellingShingle |
Consequences on anthropometry and metabolism of offspring maintenance with low-protein diet since pregnancy to adult age / Consequências sobre a antropometria e o metabolismo em ratos submetidos a dieta com baixo teor de proteínas da gravidez até a idade adulta Nascimento, Elizabeth do low-protein diet catch-up growth metabolismo rats. |
title_short |
Consequences on anthropometry and metabolism of offspring maintenance with low-protein diet since pregnancy to adult age / Consequências sobre a antropometria e o metabolismo em ratos submetidos a dieta com baixo teor de proteínas da gravidez até a idade adulta |
title_full |
Consequences on anthropometry and metabolism of offspring maintenance with low-protein diet since pregnancy to adult age / Consequências sobre a antropometria e o metabolismo em ratos submetidos a dieta com baixo teor de proteínas da gravidez até a idade adulta |
title_fullStr |
Consequences on anthropometry and metabolism of offspring maintenance with low-protein diet since pregnancy to adult age / Consequências sobre a antropometria e o metabolismo em ratos submetidos a dieta com baixo teor de proteínas da gravidez até a idade adulta |
title_full_unstemmed |
Consequences on anthropometry and metabolism of offspring maintenance with low-protein diet since pregnancy to adult age / Consequências sobre a antropometria e o metabolismo em ratos submetidos a dieta com baixo teor de proteínas da gravidez até a idade adulta |
title_sort |
Consequences on anthropometry and metabolism of offspring maintenance with low-protein diet since pregnancy to adult age / Consequências sobre a antropometria e o metabolismo em ratos submetidos a dieta com baixo teor de proteínas da gravidez até a idade adulta |
author |
Nascimento, Elizabeth do |
author_facet |
Nascimento, Elizabeth do Neto, Laércio Marques da Luz Araújo, Nathália Cavalcanti de Morais Franco, Eryvelton de Souza Muniz, Giselia de Santana |
author_role |
author |
author2 |
Neto, Laércio Marques da Luz Araújo, Nathália Cavalcanti de Morais Franco, Eryvelton de Souza Muniz, Giselia de Santana |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Nascimento, Elizabeth do Neto, Laércio Marques da Luz Araújo, Nathália Cavalcanti de Morais Franco, Eryvelton de Souza Muniz, Giselia de Santana |
dc.subject.por.fl_str_mv |
low-protein diet catch-up growth metabolismo rats. |
topic |
low-protein diet catch-up growth metabolismo rats. |
description |
The pre and early post natal is a period high susceptible to environmental insults for instance nutrition. There is a high metabolic demand necessary for the multiplication and differentiation of cells for the formation of tissues and organs and unbalanced diets affect metabolism at long term. The present study aimed to analyze physiological and metabolic parameters in male offspring submitted to the low protein diet in the perinatal life followed by a normoprotein diet or kept on the same maternal low protein diet after weaning. 12 female Wistar rats were matched with male of same strainand according maternal diet forming normoproteic and low-protein groups during gestation and lactation. At weaning three groups were randomly formed: CC (control-control), LP (low-protein-low protein) and LPC (low-protein-control). Somatic growth, feed intake, organ weight, biochemical parameters, liver fat, blood cell count and glucose tolerance test were analysed. The post-weaning "nutritional recovery" diet improved body mass and longitudinal length. But, the maintenance with low protein diet post weaning caused weight and length deficiency (P<0.001). Other parameters such as food intake, murinometric measurements, fasting gliscemia, visceral fat, organ weight, OGTT and biochemical parameters observed in the LPC were similar to CC. The LP groups caused lower area under the glycemic curve, lower visceral fat, but similar blood count, tibial growth and liver fat compared to control. The parameters evaluated in offspring submitted to nutritional recovery corroborate previous study, but the maintenance of offspring with low protein diet minimizes catch-up growth, but alters metabolic response to glucose. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-07-21 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/50494 10.34119/bjhrv5n4-093 |
url |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/50494 |
identifier_str_mv |
10.34119/bjhrv5n4-093 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/50494/pdf |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Brazilian Journal of Health Review info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Brazilian Journal of Health Review |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Brazilian Journals Publicações de Periódicos e Editora Ltda. |
publisher.none.fl_str_mv |
Brazilian Journals Publicações de Periódicos e Editora Ltda. |
dc.source.none.fl_str_mv |
Brazilian Journal of Health Review; Vol. 5 No. 4 (2022); 13111-13129 Brazilian Journal of Health Review; v. 5 n. 4 (2022); 13111-13129 2595-6825 reponame:Brazilian Journal of Health Review instname:Federação das Indústrias do Estado do Paraná (FIEP) instacron:BJRH |
instname_str |
Federação das Indústrias do Estado do Paraná (FIEP) |
instacron_str |
BJRH |
institution |
BJRH |
reponame_str |
Brazilian Journal of Health Review |
collection |
Brazilian Journal of Health Review |
repository.name.fl_str_mv |
Brazilian Journal of Health Review - Federação das Indústrias do Estado do Paraná (FIEP) |
repository.mail.fl_str_mv |
|| brazilianjhr@gmail.com |
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1797240076711755776 |