Cocoa effects on blood pressure, endothelial function, and inflammation: a systematic review
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Health Review |
Texto Completo: | https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/64569 |
Resumo: | Hypertension has affected 1,13 billion people worldwide and is one of the main risk factors for cardiovascular disease, which has a high mortality rate. The aim of the study was to review the effect of cocoa on systolic and diastolic blood pressure in hypertensive patients, and its alterations in endothelial function and inflammation. We searched PubMed, Scopus, Science Direct, Lilacs and MedLine databases in August 2018. Inclusion criteria were limited to hypertensive individuals, cardiovascular diseases, intervention and randomized clinical studies; published since 2000 and in English, Spanish and Portuguese languages. A total of 433 articles were found in the search, which 13 met the inclusion criteria. The trials had a sample of 19 to 122 participants. The cocoa was offeredas chocolate bars and cocoa beverage. Chocolate bars doses ranged from 6 g to 100 g/ day and cocoa powder doses ranged from 5 g to 31 g/ day. Intervention ranged from 2 to 18 weeks. The results observed revealed a significant blood pressure-reducing effect of cocoa, an increase in flow-mediated dilation in the evaluation of endothelial function, and no changes in antioxidant and anti-inflammatory capacity were observed after intervention. The conclusion suggests that cocoa has a blood pressure lowering effect, but new studies are still required with hypertensive individuals so that their mechanisms are better evaluates and their efficacy proven. |
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Brazilian Journal of Health Review |
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Cocoa effects on blood pressure, endothelial function, and inflammation: a systematic reviewcocoachocolatepolyphenolshypertensioninflammationHypertension has affected 1,13 billion people worldwide and is one of the main risk factors for cardiovascular disease, which has a high mortality rate. The aim of the study was to review the effect of cocoa on systolic and diastolic blood pressure in hypertensive patients, and its alterations in endothelial function and inflammation. We searched PubMed, Scopus, Science Direct, Lilacs and MedLine databases in August 2018. Inclusion criteria were limited to hypertensive individuals, cardiovascular diseases, intervention and randomized clinical studies; published since 2000 and in English, Spanish and Portuguese languages. A total of 433 articles were found in the search, which 13 met the inclusion criteria. The trials had a sample of 19 to 122 participants. The cocoa was offeredas chocolate bars and cocoa beverage. Chocolate bars doses ranged from 6 g to 100 g/ day and cocoa powder doses ranged from 5 g to 31 g/ day. Intervention ranged from 2 to 18 weeks. The results observed revealed a significant blood pressure-reducing effect of cocoa, an increase in flow-mediated dilation in the evaluation of endothelial function, and no changes in antioxidant and anti-inflammatory capacity were observed after intervention. The conclusion suggests that cocoa has a blood pressure lowering effect, but new studies are still required with hypertensive individuals so that their mechanisms are better evaluates and their efficacy proven.Brazilian Journals Publicações de Periódicos e Editora Ltda.2023-11-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/6456910.34119/bjhrv6n6-044Brazilian Journal of Health Review; Vol. 6 No. 6 (2023); 27095-27113Brazilian Journal of Health Review; Vol. 6 Núm. 6 (2023); 27095-27113Brazilian Journal of Health Review; v. 6 n. 6 (2023); 27095-271132595-6825reponame:Brazilian Journal of Health Reviewinstname:Federação das Indústrias do Estado do Paraná (FIEP)instacron:BJRHenghttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/64569/46310de Souza, Caroline Antunes Revelesde Souza, Gisele CarvalhoMiguel, Thairini de SouzaPinho Junior, Jorge da Silvade Matos , Andrea CardosoHuguenin, Grazielle Vilas Bôasinfo:eu-repo/semantics/openAccess2023-11-07T19:29:18Zoai:ojs2.ojs.brazilianjournals.com.br:article/64569Revistahttp://www.brazilianjournals.com/index.php/BJHR/indexPRIhttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/oai|| brazilianjhr@gmail.com2595-68252595-6825opendoar:2023-11-07T19:29:18Brazilian Journal of Health Review - Federação das Indústrias do Estado do Paraná (FIEP)false |
dc.title.none.fl_str_mv |
Cocoa effects on blood pressure, endothelial function, and inflammation: a systematic review |
title |
Cocoa effects on blood pressure, endothelial function, and inflammation: a systematic review |
spellingShingle |
Cocoa effects on blood pressure, endothelial function, and inflammation: a systematic review de Souza, Caroline Antunes Reveles cocoa chocolate polyphenols hypertension inflammation |
title_short |
Cocoa effects on blood pressure, endothelial function, and inflammation: a systematic review |
title_full |
Cocoa effects on blood pressure, endothelial function, and inflammation: a systematic review |
title_fullStr |
Cocoa effects on blood pressure, endothelial function, and inflammation: a systematic review |
title_full_unstemmed |
Cocoa effects on blood pressure, endothelial function, and inflammation: a systematic review |
title_sort |
Cocoa effects on blood pressure, endothelial function, and inflammation: a systematic review |
author |
de Souza, Caroline Antunes Reveles |
author_facet |
de Souza, Caroline Antunes Reveles de Souza, Gisele Carvalho Miguel, Thairini de Souza Pinho Junior, Jorge da Silva de Matos , Andrea Cardoso Huguenin, Grazielle Vilas Bôas |
author_role |
author |
author2 |
de Souza, Gisele Carvalho Miguel, Thairini de Souza Pinho Junior, Jorge da Silva de Matos , Andrea Cardoso Huguenin, Grazielle Vilas Bôas |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
de Souza, Caroline Antunes Reveles de Souza, Gisele Carvalho Miguel, Thairini de Souza Pinho Junior, Jorge da Silva de Matos , Andrea Cardoso Huguenin, Grazielle Vilas Bôas |
dc.subject.por.fl_str_mv |
cocoa chocolate polyphenols hypertension inflammation |
topic |
cocoa chocolate polyphenols hypertension inflammation |
description |
Hypertension has affected 1,13 billion people worldwide and is one of the main risk factors for cardiovascular disease, which has a high mortality rate. The aim of the study was to review the effect of cocoa on systolic and diastolic blood pressure in hypertensive patients, and its alterations in endothelial function and inflammation. We searched PubMed, Scopus, Science Direct, Lilacs and MedLine databases in August 2018. Inclusion criteria were limited to hypertensive individuals, cardiovascular diseases, intervention and randomized clinical studies; published since 2000 and in English, Spanish and Portuguese languages. A total of 433 articles were found in the search, which 13 met the inclusion criteria. The trials had a sample of 19 to 122 participants. The cocoa was offeredas chocolate bars and cocoa beverage. Chocolate bars doses ranged from 6 g to 100 g/ day and cocoa powder doses ranged from 5 g to 31 g/ day. Intervention ranged from 2 to 18 weeks. The results observed revealed a significant blood pressure-reducing effect of cocoa, an increase in flow-mediated dilation in the evaluation of endothelial function, and no changes in antioxidant and anti-inflammatory capacity were observed after intervention. The conclusion suggests that cocoa has a blood pressure lowering effect, but new studies are still required with hypertensive individuals so that their mechanisms are better evaluates and their efficacy proven. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-11-07 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/64569 10.34119/bjhrv6n6-044 |
url |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/64569 |
identifier_str_mv |
10.34119/bjhrv6n6-044 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/64569/46310 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Brazilian Journals Publicações de Periódicos e Editora Ltda. |
publisher.none.fl_str_mv |
Brazilian Journals Publicações de Periódicos e Editora Ltda. |
dc.source.none.fl_str_mv |
Brazilian Journal of Health Review; Vol. 6 No. 6 (2023); 27095-27113 Brazilian Journal of Health Review; Vol. 6 Núm. 6 (2023); 27095-27113 Brazilian Journal of Health Review; v. 6 n. 6 (2023); 27095-27113 2595-6825 reponame:Brazilian Journal of Health Review instname:Federação das Indústrias do Estado do Paraná (FIEP) instacron:BJRH |
instname_str |
Federação das Indústrias do Estado do Paraná (FIEP) |
instacron_str |
BJRH |
institution |
BJRH |
reponame_str |
Brazilian Journal of Health Review |
collection |
Brazilian Journal of Health Review |
repository.name.fl_str_mv |
Brazilian Journal of Health Review - Federação das Indústrias do Estado do Paraná (FIEP) |
repository.mail.fl_str_mv |
|| brazilianjhr@gmail.com |
_version_ |
1797240037200363520 |