Sleep pattern in transgender men on short-term cross-sex hormone therapy with testosterone
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Health Review |
Texto Completo: | https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/65548 |
Resumo: | It is believed that hormone therapy with testosterone in transgender men may interfere in the sleep quality of these patients, since testosterone may induce worsening of obstructive sleep apnea syndrome (OSAS) in hypogonadal cisgender men receiving testosterone replacement therapy. This study aims to evaluate the association between testosterone therapy and risk of sleep disorders, including OSAS, in transgender men. Eighteen transgender men in a regular and supervised use of testosterone (mean treatment time: 3 ± 1.6 years) were evaluated regarding the risk of sleep disorders through questionnaires already validated in the medical literature. Anthropometric, laboratory and clinical data were collected. According to the Epworth Sleepiness Scale (ESS), 50% of transgender men presented a risk of daytime sleepiness, while 22% and 23% of the participants were at high risk for OSAS according to the Berlin and updated STOP-Bang questionnaires, respectively. No significant association was found between risk of sleep disorders and testosterone type or therapy duration. However, there was a significant and negative correlation between androgen treatment time and ESS score. Regarding the clinical and laboratory profile of the patients, a high risk of sleep disorders was associated with lower levels of HDL cholesterol (HDL-c) and higher blood pressure values. Short-term treatment with testosterone in young transgender men is not associated with an increased risk of sleep disorders and may even improve daytime sleepiness in long-term. Blood pressure and HDL-c should be monitored in transgender men on androgen therapy as, when altered, they may indicate a higher risk of sleep disorders and OSAS. |
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Brazilian Journal of Health Review |
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Sleep pattern in transgender men on short-term cross-sex hormone therapy with testosteronetransgender personssleep disorderstestosteronehormoneIt is believed that hormone therapy with testosterone in transgender men may interfere in the sleep quality of these patients, since testosterone may induce worsening of obstructive sleep apnea syndrome (OSAS) in hypogonadal cisgender men receiving testosterone replacement therapy. This study aims to evaluate the association between testosterone therapy and risk of sleep disorders, including OSAS, in transgender men. Eighteen transgender men in a regular and supervised use of testosterone (mean treatment time: 3 ± 1.6 years) were evaluated regarding the risk of sleep disorders through questionnaires already validated in the medical literature. Anthropometric, laboratory and clinical data were collected. According to the Epworth Sleepiness Scale (ESS), 50% of transgender men presented a risk of daytime sleepiness, while 22% and 23% of the participants were at high risk for OSAS according to the Berlin and updated STOP-Bang questionnaires, respectively. No significant association was found between risk of sleep disorders and testosterone type or therapy duration. However, there was a significant and negative correlation between androgen treatment time and ESS score. Regarding the clinical and laboratory profile of the patients, a high risk of sleep disorders was associated with lower levels of HDL cholesterol (HDL-c) and higher blood pressure values. Short-term treatment with testosterone in young transgender men is not associated with an increased risk of sleep disorders and may even improve daytime sleepiness in long-term. Blood pressure and HDL-c should be monitored in transgender men on androgen therapy as, when altered, they may indicate a higher risk of sleep disorders and OSAS.Brazilian Journals Publicações de Periódicos e Editora Ltda.2023-12-13info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/6554810.34119/bjhrv6n6-366Brazilian Journal of Health Review; Vol. 6 No. 6 (2023); 31325-31337Brazilian Journal of Health Review; Vol. 6 Núm. 6 (2023); 31325-31337Brazilian Journal of Health Review; v. 6 n. 6 (2023); 31325-313372595-6825reponame:Brazilian Journal of Health Reviewinstname:Federação das Indústrias do Estado do Paraná (FIEP)instacron:BJRHenghttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/65548/46816Fernandes, Giovana GomesAlves, Humberto Costa de AraújoDezincourt, Alexandre Vasconcelosda Silva, Fábio Palma Albaradoda Silva, Rodrigo LemosCapeloni, José Roberto Bentesinfo:eu-repo/semantics/openAccess2023-12-13T12:06:34Zoai:ojs2.ojs.brazilianjournals.com.br:article/65548Revistahttp://www.brazilianjournals.com/index.php/BJHR/indexPRIhttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/oai|| brazilianjhr@gmail.com2595-68252595-6825opendoar:2023-12-13T12:06:34Brazilian Journal of Health Review - Federação das Indústrias do Estado do Paraná (FIEP)false |
dc.title.none.fl_str_mv |
Sleep pattern in transgender men on short-term cross-sex hormone therapy with testosterone |
title |
Sleep pattern in transgender men on short-term cross-sex hormone therapy with testosterone |
spellingShingle |
Sleep pattern in transgender men on short-term cross-sex hormone therapy with testosterone Fernandes, Giovana Gomes transgender persons sleep disorders testosterone hormone |
title_short |
Sleep pattern in transgender men on short-term cross-sex hormone therapy with testosterone |
title_full |
Sleep pattern in transgender men on short-term cross-sex hormone therapy with testosterone |
title_fullStr |
Sleep pattern in transgender men on short-term cross-sex hormone therapy with testosterone |
title_full_unstemmed |
Sleep pattern in transgender men on short-term cross-sex hormone therapy with testosterone |
title_sort |
Sleep pattern in transgender men on short-term cross-sex hormone therapy with testosterone |
author |
Fernandes, Giovana Gomes |
author_facet |
Fernandes, Giovana Gomes Alves, Humberto Costa de Araújo Dezincourt, Alexandre Vasconcelos da Silva, Fábio Palma Albarado da Silva, Rodrigo Lemos Capeloni, José Roberto Bentes |
author_role |
author |
author2 |
Alves, Humberto Costa de Araújo Dezincourt, Alexandre Vasconcelos da Silva, Fábio Palma Albarado da Silva, Rodrigo Lemos Capeloni, José Roberto Bentes |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Fernandes, Giovana Gomes Alves, Humberto Costa de Araújo Dezincourt, Alexandre Vasconcelos da Silva, Fábio Palma Albarado da Silva, Rodrigo Lemos Capeloni, José Roberto Bentes |
dc.subject.por.fl_str_mv |
transgender persons sleep disorders testosterone hormone |
topic |
transgender persons sleep disorders testosterone hormone |
description |
It is believed that hormone therapy with testosterone in transgender men may interfere in the sleep quality of these patients, since testosterone may induce worsening of obstructive sleep apnea syndrome (OSAS) in hypogonadal cisgender men receiving testosterone replacement therapy. This study aims to evaluate the association between testosterone therapy and risk of sleep disorders, including OSAS, in transgender men. Eighteen transgender men in a regular and supervised use of testosterone (mean treatment time: 3 ± 1.6 years) were evaluated regarding the risk of sleep disorders through questionnaires already validated in the medical literature. Anthropometric, laboratory and clinical data were collected. According to the Epworth Sleepiness Scale (ESS), 50% of transgender men presented a risk of daytime sleepiness, while 22% and 23% of the participants were at high risk for OSAS according to the Berlin and updated STOP-Bang questionnaires, respectively. No significant association was found between risk of sleep disorders and testosterone type or therapy duration. However, there was a significant and negative correlation between androgen treatment time and ESS score. Regarding the clinical and laboratory profile of the patients, a high risk of sleep disorders was associated with lower levels of HDL cholesterol (HDL-c) and higher blood pressure values. Short-term treatment with testosterone in young transgender men is not associated with an increased risk of sleep disorders and may even improve daytime sleepiness in long-term. Blood pressure and HDL-c should be monitored in transgender men on androgen therapy as, when altered, they may indicate a higher risk of sleep disorders and OSAS. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-12-13 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/65548 10.34119/bjhrv6n6-366 |
url |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/65548 |
identifier_str_mv |
10.34119/bjhrv6n6-366 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/65548/46816 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Brazilian Journals Publicações de Periódicos e Editora Ltda. |
publisher.none.fl_str_mv |
Brazilian Journals Publicações de Periódicos e Editora Ltda. |
dc.source.none.fl_str_mv |
Brazilian Journal of Health Review; Vol. 6 No. 6 (2023); 31325-31337 Brazilian Journal of Health Review; Vol. 6 Núm. 6 (2023); 31325-31337 Brazilian Journal of Health Review; v. 6 n. 6 (2023); 31325-31337 2595-6825 reponame:Brazilian Journal of Health Review instname:Federação das Indústrias do Estado do Paraná (FIEP) instacron:BJRH |
instname_str |
Federação das Indústrias do Estado do Paraná (FIEP) |
instacron_str |
BJRH |
institution |
BJRH |
reponame_str |
Brazilian Journal of Health Review |
collection |
Brazilian Journal of Health Review |
repository.name.fl_str_mv |
Brazilian Journal of Health Review - Federação das Indústrias do Estado do Paraná (FIEP) |
repository.mail.fl_str_mv |
|| brazilianjhr@gmail.com |
_version_ |
1797240039074168832 |