Pregnancy outcomes in young mothers with perinatally and behaviorally acquired HIV infections in Rio de Janeiro
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Infectious Diseases |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000500412 |
Resumo: | ABSTRACT Background: Perinatally HIV-infected children are surviving into adulthood, and getting pregnant. There is a scarcity of information on health and pregnancy outcomes in these women. Aim: To evaluate characteristics related to HIV disease and pregnancy outcomes in perinatally infected women, and to compare these women with a group of youth with behaviorally acquired HIV-infection, at a reference hospital in Rio de Janeiro, Brazil. Methods: A cohort study. Epidemiological, clinical, and laboratory data were compared between perinatally (PHIV) and behaviorally HIV-infected (BHIV) pregnant youth with the primary aim to study pregnancy outcomes in the PHIV group and compare with outcomes to BHIV group. Results: Thirty-two pregnancies occurred in PHIV group, and 595 in BHIV group. A total of seven (22%) PHIV women and 64 (11%) BHIV women had a premature delivery (p = 0.04), however, when adjusting for younger age at pregnancy, and antiretroviral therapy initiation in 1st trimester of pregnancy (OR = 18.66, 95%CI = 5.52–63.14), the difference was no longer significant. No cases of mother-to-child HIV transmission (MTCT) were observed in the PHIV group while there was a 2% MTCT rate in BHIV group. Conclusion: Pregnancy among PHIV was as safe as among BHIV. The differences between those groups were probably related to treatment and prolonged care in the first group. |
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Brazilian Journal of Infectious Diseases |
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Pregnancy outcomes in young mothers with perinatally and behaviorally acquired HIV infections in Rio de JaneiroPerinatal HIVPregnancyMother-to-child transmissionCombined antiretroviral treatmentABSTRACT Background: Perinatally HIV-infected children are surviving into adulthood, and getting pregnant. There is a scarcity of information on health and pregnancy outcomes in these women. Aim: To evaluate characteristics related to HIV disease and pregnancy outcomes in perinatally infected women, and to compare these women with a group of youth with behaviorally acquired HIV-infection, at a reference hospital in Rio de Janeiro, Brazil. Methods: A cohort study. Epidemiological, clinical, and laboratory data were compared between perinatally (PHIV) and behaviorally HIV-infected (BHIV) pregnant youth with the primary aim to study pregnancy outcomes in the PHIV group and compare with outcomes to BHIV group. Results: Thirty-two pregnancies occurred in PHIV group, and 595 in BHIV group. A total of seven (22%) PHIV women and 64 (11%) BHIV women had a premature delivery (p = 0.04), however, when adjusting for younger age at pregnancy, and antiretroviral therapy initiation in 1st trimester of pregnancy (OR = 18.66, 95%CI = 5.52–63.14), the difference was no longer significant. No cases of mother-to-child HIV transmission (MTCT) were observed in the PHIV group while there was a 2% MTCT rate in BHIV group. Conclusion: Pregnancy among PHIV was as safe as among BHIV. The differences between those groups were probably related to treatment and prolonged care in the first group.Brazilian Society of Infectious Diseases2018-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000500412Brazilian Journal of Infectious Diseases v.22 n.5 2018reponame:Brazilian Journal of Infectious Diseasesinstname:Brazilian Society of Infectious Diseases (BSID)instacron:BSID10.1016/j.bjid.2018.08.005info:eu-repo/semantics/openAccessLundberg,PerAndersson,RuneMachado,Elizabeth S.Costa,Tomaz Pinheiro daHofer,Cristina Barrosoeng2018-12-14T00:00:00Zoai:scielo:S1413-86702018000500412Revistahttps://www.bjid.org.br/https://old.scielo.br/oai/scielo-oai.phpbjid@bjid.org.br||lgoldani@ufrgs.br1678-43911413-8670opendoar:2018-12-14T00:00Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)false |
dc.title.none.fl_str_mv |
Pregnancy outcomes in young mothers with perinatally and behaviorally acquired HIV infections in Rio de Janeiro |
title |
Pregnancy outcomes in young mothers with perinatally and behaviorally acquired HIV infections in Rio de Janeiro |
spellingShingle |
Pregnancy outcomes in young mothers with perinatally and behaviorally acquired HIV infections in Rio de Janeiro Lundberg,Per Perinatal HIV Pregnancy Mother-to-child transmission Combined antiretroviral treatment |
title_short |
Pregnancy outcomes in young mothers with perinatally and behaviorally acquired HIV infections in Rio de Janeiro |
title_full |
Pregnancy outcomes in young mothers with perinatally and behaviorally acquired HIV infections in Rio de Janeiro |
title_fullStr |
Pregnancy outcomes in young mothers with perinatally and behaviorally acquired HIV infections in Rio de Janeiro |
title_full_unstemmed |
Pregnancy outcomes in young mothers with perinatally and behaviorally acquired HIV infections in Rio de Janeiro |
title_sort |
Pregnancy outcomes in young mothers with perinatally and behaviorally acquired HIV infections in Rio de Janeiro |
author |
Lundberg,Per |
author_facet |
Lundberg,Per Andersson,Rune Machado,Elizabeth S. Costa,Tomaz Pinheiro da Hofer,Cristina Barroso |
author_role |
author |
author2 |
Andersson,Rune Machado,Elizabeth S. Costa,Tomaz Pinheiro da Hofer,Cristina Barroso |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Lundberg,Per Andersson,Rune Machado,Elizabeth S. Costa,Tomaz Pinheiro da Hofer,Cristina Barroso |
dc.subject.por.fl_str_mv |
Perinatal HIV Pregnancy Mother-to-child transmission Combined antiretroviral treatment |
topic |
Perinatal HIV Pregnancy Mother-to-child transmission Combined antiretroviral treatment |
description |
ABSTRACT Background: Perinatally HIV-infected children are surviving into adulthood, and getting pregnant. There is a scarcity of information on health and pregnancy outcomes in these women. Aim: To evaluate characteristics related to HIV disease and pregnancy outcomes in perinatally infected women, and to compare these women with a group of youth with behaviorally acquired HIV-infection, at a reference hospital in Rio de Janeiro, Brazil. Methods: A cohort study. Epidemiological, clinical, and laboratory data were compared between perinatally (PHIV) and behaviorally HIV-infected (BHIV) pregnant youth with the primary aim to study pregnancy outcomes in the PHIV group and compare with outcomes to BHIV group. Results: Thirty-two pregnancies occurred in PHIV group, and 595 in BHIV group. A total of seven (22%) PHIV women and 64 (11%) BHIV women had a premature delivery (p = 0.04), however, when adjusting for younger age at pregnancy, and antiretroviral therapy initiation in 1st trimester of pregnancy (OR = 18.66, 95%CI = 5.52–63.14), the difference was no longer significant. No cases of mother-to-child HIV transmission (MTCT) were observed in the PHIV group while there was a 2% MTCT rate in BHIV group. Conclusion: Pregnancy among PHIV was as safe as among BHIV. The differences between those groups were probably related to treatment and prolonged care in the first group. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000500412 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000500412 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.bjid.2018.08.005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
dc.source.none.fl_str_mv |
Brazilian Journal of Infectious Diseases v.22 n.5 2018 reponame:Brazilian Journal of Infectious Diseases instname:Brazilian Society of Infectious Diseases (BSID) instacron:BSID |
instname_str |
Brazilian Society of Infectious Diseases (BSID) |
instacron_str |
BSID |
institution |
BSID |
reponame_str |
Brazilian Journal of Infectious Diseases |
collection |
Brazilian Journal of Infectious Diseases |
repository.name.fl_str_mv |
Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID) |
repository.mail.fl_str_mv |
bjid@bjid.org.br||lgoldani@ufrgs.br |
_version_ |
1754209244592209920 |