Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Infectious Diseases |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000300019 |
Resumo: | Aureobasidium pullulans is a causal agent of phaeohyphomycosis, occasionally found in men and animals. As an agent of different opportunistic fungal processes, it may cause fungemia, systemic infections and abscesses in different viscera. This paper aims to report a case of a patient with infection of the lymphatic system by A. pullulans. A 23-year-old patient being treated for erythema nodosum leprosum presented a 60-day complaint of daily fever, hoarseness, odynophagia and weight loss. Laboratory tests showed pancytopenia with severe neutropenia, cervical adenomegaly and solid contrast uptake lesion in the oropharyngeal region. Due to neutropenia and sepsis the patient was initially treated with cefepime and vancomycin, but there was no clinical improvement. Lymph node puncture-aspiration showed yeast-form fungus identified as A. pullulans by sequencing ITS region. The patient was treated with amphotericin B deoxycholate, leading to complete recovery of bone marrow function and regression of adenomegaly and the oropharyngeal lesion. |
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Brazilian Journal of Infectious Diseases |
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Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosumHIVpneumoniamacrolidesmortalityAureobasidium pullulans is a causal agent of phaeohyphomycosis, occasionally found in men and animals. As an agent of different opportunistic fungal processes, it may cause fungemia, systemic infections and abscesses in different viscera. This paper aims to report a case of a patient with infection of the lymphatic system by A. pullulans. A 23-year-old patient being treated for erythema nodosum leprosum presented a 60-day complaint of daily fever, hoarseness, odynophagia and weight loss. Laboratory tests showed pancytopenia with severe neutropenia, cervical adenomegaly and solid contrast uptake lesion in the oropharyngeal region. Due to neutropenia and sepsis the patient was initially treated with cefepime and vancomycin, but there was no clinical improvement. Lymph node puncture-aspiration showed yeast-form fungus identified as A. pullulans by sequencing ITS region. The patient was treated with amphotericin B deoxycholate, leading to complete recovery of bone marrow function and regression of adenomegaly and the oropharyngeal lesion.Brazilian Society of Infectious Diseases2011-06-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000300019Brazilian Journal of Infectious Diseases v.15 n.3 2011reponame:Brazilian Journal of Infectious Diseasesinstname:Brazilian Society of Infectious Diseases (BSID)instacron:BSID10.1590/S1413-86702011000300019info:eu-repo/semantics/openAccessMorais,Orlando Oliveira dePorto,CláudiaCoutinho,Anglya Samara Silva LeiteReis,Carmélia Matos SantiagoTeixeira,Marcus de MeloGomes,Ciro Martinseng2011-06-06T00:00:00Zoai:scielo:S1413-86702011000300019Revistahttps://www.bjid.org.br/https://old.scielo.br/oai/scielo-oai.phpbjid@bjid.org.br||lgoldani@ufrgs.br1678-43911413-8670opendoar:2011-06-06T00:00Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)false |
dc.title.none.fl_str_mv |
Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum |
title |
Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum |
spellingShingle |
Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum Morais,Orlando Oliveira de HIV pneumonia macrolides mortality |
title_short |
Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum |
title_full |
Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum |
title_fullStr |
Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum |
title_full_unstemmed |
Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum |
title_sort |
Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum |
author |
Morais,Orlando Oliveira de |
author_facet |
Morais,Orlando Oliveira de Porto,Cláudia Coutinho,Anglya Samara Silva Leite Reis,Carmélia Matos Santiago Teixeira,Marcus de Melo Gomes,Ciro Martins |
author_role |
author |
author2 |
Porto,Cláudia Coutinho,Anglya Samara Silva Leite Reis,Carmélia Matos Santiago Teixeira,Marcus de Melo Gomes,Ciro Martins |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Morais,Orlando Oliveira de Porto,Cláudia Coutinho,Anglya Samara Silva Leite Reis,Carmélia Matos Santiago Teixeira,Marcus de Melo Gomes,Ciro Martins |
dc.subject.por.fl_str_mv |
HIV pneumonia macrolides mortality |
topic |
HIV pneumonia macrolides mortality |
description |
Aureobasidium pullulans is a causal agent of phaeohyphomycosis, occasionally found in men and animals. As an agent of different opportunistic fungal processes, it may cause fungemia, systemic infections and abscesses in different viscera. This paper aims to report a case of a patient with infection of the lymphatic system by A. pullulans. A 23-year-old patient being treated for erythema nodosum leprosum presented a 60-day complaint of daily fever, hoarseness, odynophagia and weight loss. Laboratory tests showed pancytopenia with severe neutropenia, cervical adenomegaly and solid contrast uptake lesion in the oropharyngeal region. Due to neutropenia and sepsis the patient was initially treated with cefepime and vancomycin, but there was no clinical improvement. Lymph node puncture-aspiration showed yeast-form fungus identified as A. pullulans by sequencing ITS region. The patient was treated with amphotericin B deoxycholate, leading to complete recovery of bone marrow function and regression of adenomegaly and the oropharyngeal lesion. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000300019 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000300019 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1413-86702011000300019 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
dc.source.none.fl_str_mv |
Brazilian Journal of Infectious Diseases v.15 n.3 2011 reponame:Brazilian Journal of Infectious Diseases instname:Brazilian Society of Infectious Diseases (BSID) instacron:BSID |
instname_str |
Brazilian Society of Infectious Diseases (BSID) |
instacron_str |
BSID |
institution |
BSID |
reponame_str |
Brazilian Journal of Infectious Diseases |
collection |
Brazilian Journal of Infectious Diseases |
repository.name.fl_str_mv |
Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID) |
repository.mail.fl_str_mv |
bjid@bjid.org.br||lgoldani@ufrgs.br |
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1754209241905758208 |