Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum

Detalhes bibliográficos
Autor(a) principal: Morais,Orlando Oliveira de
Data de Publicação: 2011
Outros Autores: Porto,Cláudia, Coutinho,Anglya Samara Silva Leite, Reis,Carmélia Matos Santiago, Teixeira,Marcus de Melo, Gomes,Ciro Martins
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Brazilian Journal of Infectious Diseases
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000300019
Resumo: Aureobasidium pullulans is a causal agent of phaeohyphomycosis, occasionally found in men and animals. As an agent of different opportunistic fungal processes, it may cause fungemia, systemic infections and abscesses in different viscera. This paper aims to report a case of a patient with infection of the lymphatic system by A. pullulans. A 23-year-old patient being treated for erythema nodosum leprosum presented a 60-day complaint of daily fever, hoarseness, odynophagia and weight loss. Laboratory tests showed pancytopenia with severe neutropenia, cervical adenomegaly and solid contrast uptake lesion in the oropharyngeal region. Due to neutropenia and sepsis the patient was initially treated with cefepime and vancomycin, but there was no clinical improvement. Lymph node puncture-aspiration showed yeast-form fungus identified as A. pullulans by sequencing ITS region. The patient was treated with amphotericin B deoxycholate, leading to complete recovery of bone marrow function and regression of adenomegaly and the oropharyngeal lesion.
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spelling Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosumHIVpneumoniamacrolidesmortalityAureobasidium pullulans is a causal agent of phaeohyphomycosis, occasionally found in men and animals. As an agent of different opportunistic fungal processes, it may cause fungemia, systemic infections and abscesses in different viscera. This paper aims to report a case of a patient with infection of the lymphatic system by A. pullulans. A 23-year-old patient being treated for erythema nodosum leprosum presented a 60-day complaint of daily fever, hoarseness, odynophagia and weight loss. Laboratory tests showed pancytopenia with severe neutropenia, cervical adenomegaly and solid contrast uptake lesion in the oropharyngeal region. Due to neutropenia and sepsis the patient was initially treated with cefepime and vancomycin, but there was no clinical improvement. Lymph node puncture-aspiration showed yeast-form fungus identified as A. pullulans by sequencing ITS region. The patient was treated with amphotericin B deoxycholate, leading to complete recovery of bone marrow function and regression of adenomegaly and the oropharyngeal lesion.Brazilian Society of Infectious Diseases2011-06-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000300019Brazilian Journal of Infectious Diseases v.15 n.3 2011reponame:Brazilian Journal of Infectious Diseasesinstname:Brazilian Society of Infectious Diseases (BSID)instacron:BSID10.1590/S1413-86702011000300019info:eu-repo/semantics/openAccessMorais,Orlando Oliveira dePorto,CláudiaCoutinho,Anglya Samara Silva LeiteReis,Carmélia Matos SantiagoTeixeira,Marcus de MeloGomes,Ciro Martinseng2011-06-06T00:00:00Zoai:scielo:S1413-86702011000300019Revistahttps://www.bjid.org.br/https://old.scielo.br/oai/scielo-oai.phpbjid@bjid.org.br||lgoldani@ufrgs.br1678-43911413-8670opendoar:2011-06-06T00:00Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)false
dc.title.none.fl_str_mv Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
title Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
spellingShingle Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
Morais,Orlando Oliveira de
HIV
pneumonia
macrolides
mortality
title_short Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
title_full Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
title_fullStr Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
title_full_unstemmed Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
title_sort Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
author Morais,Orlando Oliveira de
author_facet Morais,Orlando Oliveira de
Porto,Cláudia
Coutinho,Anglya Samara Silva Leite
Reis,Carmélia Matos Santiago
Teixeira,Marcus de Melo
Gomes,Ciro Martins
author_role author
author2 Porto,Cláudia
Coutinho,Anglya Samara Silva Leite
Reis,Carmélia Matos Santiago
Teixeira,Marcus de Melo
Gomes,Ciro Martins
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Morais,Orlando Oliveira de
Porto,Cláudia
Coutinho,Anglya Samara Silva Leite
Reis,Carmélia Matos Santiago
Teixeira,Marcus de Melo
Gomes,Ciro Martins
dc.subject.por.fl_str_mv HIV
pneumonia
macrolides
mortality
topic HIV
pneumonia
macrolides
mortality
description Aureobasidium pullulans is a causal agent of phaeohyphomycosis, occasionally found in men and animals. As an agent of different opportunistic fungal processes, it may cause fungemia, systemic infections and abscesses in different viscera. This paper aims to report a case of a patient with infection of the lymphatic system by A. pullulans. A 23-year-old patient being treated for erythema nodosum leprosum presented a 60-day complaint of daily fever, hoarseness, odynophagia and weight loss. Laboratory tests showed pancytopenia with severe neutropenia, cervical adenomegaly and solid contrast uptake lesion in the oropharyngeal region. Due to neutropenia and sepsis the patient was initially treated with cefepime and vancomycin, but there was no clinical improvement. Lymph node puncture-aspiration showed yeast-form fungus identified as A. pullulans by sequencing ITS region. The patient was treated with amphotericin B deoxycholate, leading to complete recovery of bone marrow function and regression of adenomegaly and the oropharyngeal lesion.
publishDate 2011
dc.date.none.fl_str_mv 2011-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000300019
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000300019
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1413-86702011000300019
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Brazilian Society of Infectious Diseases
publisher.none.fl_str_mv Brazilian Society of Infectious Diseases
dc.source.none.fl_str_mv Brazilian Journal of Infectious Diseases v.15 n.3 2011
reponame:Brazilian Journal of Infectious Diseases
instname:Brazilian Society of Infectious Diseases (BSID)
instacron:BSID
instname_str Brazilian Society of Infectious Diseases (BSID)
instacron_str BSID
institution BSID
reponame_str Brazilian Journal of Infectious Diseases
collection Brazilian Journal of Infectious Diseases
repository.name.fl_str_mv Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)
repository.mail.fl_str_mv bjid@bjid.org.br||lgoldani@ufrgs.br
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